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5I6A
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BICYCLO[3.3.2]DECAPEPTIDE
Descriptor:ALA-PHE-GLY-LYD-VAL-PHE-PRO-GLN-ALA-GLY, DIMETHYL SULFOXIDE
Authors:Bartoloni, M., Waltersperger, S., Bumann, M., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2016-02-16
Release date:2016-03-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (0.813 Å)
Cite:Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide
Arkivoc, 2014, 2014
3ZYB
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CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION
Descriptor:PA-I galactophilic lectin, GALA-LYS-PRO-LEUNH2, CALCIUM ION, ...
Authors:Kadam, R.U., Bergmann, M., Hurley, M., Garg, D., Cacciarini, M., Swiderska, M.A., Nativi, C., Sattler, M., Smyth, A.R., Williams, P., Camara, M., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2011-08-19
Release date:2011-09-21
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms.
Angew.Chem.Int.Ed.Engl., 50, 2011
3ZYF
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CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTION
Descriptor:PA-I GALACTOPHILIC LECTIN, CALCIUM ION, 1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE
Authors:Kadam, R.U., Bergmann, M., Hurley, M., Garg, D., Cacciarini, M., Swiderska, M.A., Nativi, C., Sattler, M., Smyth, A.R., Williams, P., Camara, M., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2011-08-22
Release date:2011-09-21
Last modified:2012-04-25
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms.
Angew.Chem.Int.Ed.Engl., 50, 2011
3ZYH
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CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALBG0 AT 1.5 A RESOLUTION
Descriptor:PA-I galactophilic lectin, CALCIUM ION, 3-(beta-D-galactopyranosylthio)propanoic acid
Authors:Kadam, R.U., Bergmann, M., Hurley, M., Garg, D., Cacciarini, M., Swiderska, M.A., Nativi, C., Sattler, M., Smyth, A.R., Williams, P., Camara, M., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2011-08-23
Release date:2011-09-21
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:A Glycopeptide Dendrimer Inhibitor of the Galactose Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms
Angew.Chem.Int.Ed.Engl., 50, 2011
4LKD
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH GALA-QRS AT 2.31 A RESOLUTION
Descriptor:PA-I galactophilic lectin, peptide QRSA, BETA-D-GALACTOSE, ...
Authors:Kadam, R.U., Stocker, A., Reymond, J.-L.
Deposit date:2013-07-07
Release date:2013-12-18
Method:X-RAY DIFFRACTION (2.307 Å)
Cite:Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.
Chemistry, 19, 2013
4LKE
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH GALA-WRI AT 1.65 A RESOLUTION
Descriptor:PA-I galactophilic lectin, peptide WRIA, BETA-D-GALACTOSE, ...
Authors:Kadam, R.U., Stocker, A., Reymond, J.-L.
Deposit date:2013-07-07
Release date:2013-12-18
Method:X-RAY DIFFRACTION (1.653 Å)
Cite:Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.
Chemistry, 19, 2013
4LKF
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN LECA COMPLEXED WITH GALA-WKY AT 1.64 A RESOLUTION
Descriptor:PA-I galactophilic lectin, peptide WKYL, BETA-D-GALACTOSE, ...
Authors:Kadam, R.U., Stocker, A., Reymond, J.-L.
Deposit date:2013-07-07
Release date:2013-12-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA.
Chemistry, 19, 2013
6S5P
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CFUCOSYLATED PEPTIDE SBL2 BOUND TO FUCOSE BINDING LECTIN LECB (PA-IIL) FROM PSEUDOMONAS AERUGINOSA AT 1.46 ANGSTROM RESOLUTION
Descriptor:Fucose-binding lectin, SBL2, CALCIUM ION, ...
Authors:Baeriswyl, S., Stocker, A., Reymond, J.-L.
Deposit date:2019-07-02
Release date:2019-08-21
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:X-Ray Crystal Structure of a Second Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB
Helv.Chim.Acta, 2019
6S5R
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CFUCOSYLATED SECOND GENERATION PEPTIDE DENDRIMER SBD6 BOUND TO FUCOSE BINDING LECTIN LECB (PA-IIL) FROM PSEUDOMONAS AERUGINOSA AT 2.08 ANGSTROM RESOLUTION, INCOMPLETE STRUCTURE
Descriptor:Fucose-binding lectin, SBD6, CALCIUM ION, ...
Authors:Baeriswyl, S., Stocker, A., Reymond, J.-L.
Deposit date:2019-07-02
Release date:2019-08-21
Method:X-RAY DIFFRACTION (2.076 Å)
Cite:X-Ray Crystal Structure of a Second Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB
Helv.Chim.Acta, 2019
6S5S
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CFUCOSYLATED SECOND GENERATION PEPTIDE DENDRIMER SBD8 BOUND TO FUCOSE BINDING LECTIN LECB (PA-IIL) FROM PSEUDOMONAS AERUGINOSA AT 1.43 ANGSTROM RESOLUTION
Descriptor:Fucose-binding lectin, SBD8 chain B, SBD8 chain C, ...
Authors:Baeriswyl, S., Stocker, A., Reymond, J.-L.
Deposit date:2019-07-02
Release date:2019-08-21
Method:X-RAY DIFFRACTION (1.433 Å)
Cite:X-Ray Crystal Structure of a Second Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB
Helv.Chim.Acta, 2019
6S7G
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CFUCOSYLATED LINKER PEPTIDE SBL1 BOUND TO FUCOSE BINDING LECTIN LECB (PA-IIL) FROM PSEUDOMONAS AERUGINOSA AT 1.84 ANGSTROM RESOLUTION
Descriptor:Fucose-binding lectin, SBL1, CALCIUM ION, ...
Authors:Baeriswyl, S., Stocker, A., Reymond, J.-L.
Deposit date:2019-07-04
Release date:2019-08-21
Method:X-RAY DIFFRACTION (1.841 Å)
Cite:X-Ray Crystal Structure of a Second Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB
Helv.Chim.Acta, 2019
5NES
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DISCOVERY, CRYSTAL STRUCTURES AND ATOMIC FORCE MICROSCOPY STUDY OF THIOETHER LIGATED D,L-CYCLIC ANTIMICROBIAL PEPTIDES AGAINST MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA
Descriptor:Fucose-binding lectin II (PA-IIL), CYD-TRP-TRD-LYS-LYD-LYS-LYD-LYS-TRD-TRP-CYD, CALCIUM ION, ...
Authors:Reymond, J.-L., Darbre, T., Stocker, A., Hong, W., van Delden, C., Koehler, T., Luscher, A., Visini, R., Fu, Y., Di Bonaventura, I., He, R.
Deposit date:2017-03-11
Release date:2017-09-13
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.606 Å)
Cite:Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.
Chem Sci, 8, 2017
5NEY
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DISCOVERY, CRYSTAL STRUCTURES AND ATOMIC FORCE MICROSCOPY STUDY OF THIOETHER LIGATED D,L-CYCLIC ANTIMICROBIAL PEPTIDES AGAINST MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA
Descriptor:Fucose-binding lectin II (PA-IIL), CYS-TRD-TRP-LYD-LYS-LYD-LYS-LYD-TRP-TRD-CYS-ALA, 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, ...
Authors:Reymond, J.-L., Darbre, T., Stocker, A., Hong, W., van Delden, C., Koehler, T., Luscher, A., Visini, R., Fu, Y., Di Bonaventura, I., He, R.
Deposit date:2017-03-13
Release date:2017-09-13
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.
Chem Sci, 8, 2017
5NF0
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DISCOVERY, CRYSTAL STRUCTURES AND ATOMIC FORCE MICROSCOPY STUDY OF THIOETHER LIGATED D,L-CYCLIC ANTIMICROBIAL PEPTIDES AGAINST MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA
Descriptor:Fucose-binding lectin II (PA-IIL), CYD-TRP-TRD-LYS-LYD-LYS-LYD-LYS-TRD-TRP-CYD-GLY, Fragment of ligand, ...
Authors:Reymond, J.-L., Darbre, T., Stocker, A., Hong, W., van Delden, C., Koehler, T., Luscher, A., Visini, R., Fu, Y., Di Bonaventura, I., He, R.
Deposit date:2017-03-13
Release date:2017-09-13
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.271 Å)
Cite:Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa.
Chem Sci, 8, 2017
4YW6
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STRUCTURAL INSIGHT INTO DIVALENT GALACTOSIDE BINDING TO PSEUDOMONAS AERUGINOSA LECTIN LECA
Descriptor:PA-I galactophilic lectin, CALCIUM ION, N-[(2S)-6-amino-1-oxo-1-(pyrrolidin-1-yl)hexan-2-yl]-4-(beta-D-galactopyranosyloxy)benzamide
Authors:Visini, R., Jin, X., Michaud, G., Bergmann, M., Gillon, E., Imberty, A., Stocker, A., Darbre, T., Pieters, R., Reymond, J.-L.
Deposit date:2015-03-20
Release date:2015-09-09
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA.
Acs Chem.Biol., 10, 2015
4YW7
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STRUCTURAL INSIGHT INTO DIVALENT GALACTOSIDE BINDING TO PSEUDOMONAS AERUGINOSA LECTIN LECA
Descriptor:PA-I galactophilic lectin, CALCIUM ION, BETA-D-GALACTOSE, ...
Authors:Visini, R., Jin, X., Michaud, G., Bergmann, M., Gillon, E., Imberty, A., Stocker, A., Darbre, T., Pieters, R., Reymond, J.-L.
Deposit date:2015-03-20
Release date:2015-09-09
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA.
Acs Chem.Biol., 10, 2015
4YWA
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STRUCTURAL INSIGHT INTO DIVALENT GALACTOSIDE BINDING TO PSEUDOMONAS AERUGINOSA LECTIN LECA
Descriptor:PA-I galactophilic lectin, CALCIUM ION, (2R,3R,4S,5R,6R,2'R,3'R,4'S,5'R,6'R)-2,2'-([(2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diyl]bis{1H-1,2,3-triazole-1,4-diyl[(2S,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diyl]-1H-1,2,3-triazole-1,4-diylmethanediyloxy})bis[6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol]
Authors:Visini, R., Jin, X., Michaud, G., Bergmann, M., Gillon, E., Imberty, A., Stocker, A., Darbre, T., Pieters, R., Reymond, J.-L.
Deposit date:2015-03-20
Release date:2015-09-09
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (1.192 Å)
Cite:Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA.
Acs Chem.Biol., 10, 2015
5D21
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MULTIVALENCY EFFECTS IN GLYCOPEPTIDE DENDRIMER INHIBITORS OF PSEUDOMONAS AERUGINOSA BIOFILMS TARGETING LECTIN LECA
Descriptor:LecA, CALCIUM ION, phenyl beta-D-galactopyranoside
Authors:Bergmann, M., Michaud, G., Visini, R., Jin, X., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2015-08-05
Release date:2015-11-25
Last modified:2015-12-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multivalency effects on Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA.
Org.Biomol.Chem., 14, 2016
5I8M
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BICYCLIC ANTIMIBROCIAL PEPTIDES
Descriptor:Fucose-binding lectin, DLS-LYS-CYS-LYS-LEU-CYS-LEU-LYS-NH2, CALCIUM ION, ...
Authors:Di Bonaventura, I., Jin, X., Visini, R., Michaud, G., Robadey, M., Koehler, T., van Delden, C., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2016-02-19
Release date:2017-08-23
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms.
Chem Sci, 8, 2017
5I8X
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BICYCLIC ANTIMIBROCIAL PEPTIDES
Descriptor:Fucose-binding lectin, DLS-LYS-CYS-LYS-LEU-CYS-LYS-LYS-NH2, 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, ...
Authors:Di Bonaventura, I., Jin, X., Visini, R., Michaud, G., Robadey, M., Koehler, T., van Delden, C., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2016-02-19
Release date:2017-08-23
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms.
Chem Sci, 8, 2017
5NGQ
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BICYCLIC ANTIMICROBIAL PEPTIDES
Descriptor:Fucose-binding lectin II (PA-IIL), DLS-PRO-ALD-CYS-TYD-ALA-CYD-LYS-ALA, Fragment of bicycle, ...
Authors:Di Bonaventura, I., Jin, X., Visini, R., Michaud, G., Robadey, M., Koehler, T., van Delden, C., Stocker, A., Darbre, T., Reymond, J.-L.
Deposit date:2017-03-20
Release date:2017-08-23
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms.
Chem Sci, 8, 2017
5OGL
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STRUCTURE OF BACTERIAL OLIGOSACCHARYLTRANSFERASE PGLB IN COMPLEX WITH AN ACCEPTOR PEPTIDE AND AN LIPID-LINKED OLIGOSACCHARIDE ANALOG
Descriptor:Undecaprenyl-diphosphooligosaccharide--protein glycotransferase, Substrate mimicking peptide, MANGANESE (II) ION, ...
Authors:Napiorkowska, M., Boilevin, J., Sovdat, T., Darbre, T., Reymond, J.-L., Aebi, M., Locher, K.P.
Deposit date:2017-07-13
Release date:2017-10-25
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase.
Nat. Struct. Mol. Biol., 24, 2017
6GXC
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BACTERIAL OLIGOSACCHARYLTRANSFERASE PGLB IN COMPLEX WITH AN INHIBITORY PEPTIDE AND A REACTIVE LIPID-LINKED OLIGOSACCHARIDE ANALOG
Descriptor:Undecaprenyl-diphosphooligosaccharide--protein glycotransferase, GLY-ASP-GLN-DAB-ALA-THR-PPN-GLY, MANGANESE (II) ION, ...
Authors:Napiorkowska, M., Locher, K.P., Boilevin, J., Darbre, T., Reymond, J.-L.
Deposit date:2018-06-27
Release date:2018-11-14
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide.
Sci Rep, 8, 2018
6Q6X
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STRUCTURE OF FUCOSYLATED D-ANTIMICROBIAL PEPTIDE SB6 IN COMPLEX WITH THE FUCOSE-BINDING LECTIN PA-IIL AT 1.525 ANGSTROM RESOLUTION
Descriptor:Fucose-binding lectin, SB6, CALCIUM ION, ...
Authors:Baeriswyl, S., Stocker, A., Reymond, J.-L.
Deposit date:2018-12-12
Release date:2019-03-20
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (1.525 Å)
Cite:X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.
Acs Chem.Biol., 14, 2019
6Q77
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STRUCTURE OF FUCOSYLATED D-ANTIMICROBIAL PEPTIDE SB12 IN COMPLEX WITH THE FUCOSE-BINDING LECTIN PA-IIL AT 2.002 ANGSTROM RESOLUTION
Descriptor:Fucose-binding lectin, SB12, CALCIUM ION, ...
Authors:Baeriswyl, S., Stocker, A., Reymond, J.-L.
Deposit date:2018-12-12
Release date:2019-03-20
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.
Acs Chem.Biol., 14, 2019
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