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5NP2
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ABL1 SH3 PTYR89/134
Descriptor:Tyrosine-protein kinase ABL1
Authors:Mero, B., Radnai, L., Gogl, G., Leveles, I., Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP3
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ABL2 SH3
Descriptor:Abelson tyrosine-protein kinase 2
Authors:Mero, B., Radnai, L., Gogl, G., Leveles, I., Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP5
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ABL2 SH3 PTYR116/161
Descriptor:Abelson tyrosine-protein kinase 2, SULFATE ION
Authors:Mero, B., Radnai, L., Gogl, G., Leveles, I., Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
2XQQ
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE (AC-SRGTQTE).
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, SAC-ARG-GLY-THR-GLN-THR-GLU, ...
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-09-07
Release date:2011-05-04
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
Plos One, 6, 2011
3P8M
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE DIMERIZED BY LEUCINE ZIPPER
Descriptor:Dynein light chain 2, General control protein GCN4
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-10-14
Release date:2011-08-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
3ZWH
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CA2+-BOUND S100A4 C3S, C81S, C86S AND F45W MUTANT COMPLEXED WITH MYOSIN IIA
Descriptor:PROTEIN S100-A4, MYOSIN-9, CALCIUM ION, ...
Authors:Kiss, B., Duelli, A., Radnai, L., Kekesi, A.K., Katona, G., Nyitray, L.
Deposit date:2011-07-31
Release date:2012-04-04
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal Structure of the S100A4-Nonmuscle Myosin Iia Tail Fragment Complex Reveals an Asymmetric Target Binding Mechanism.
Proc.Natl.Acad.Sci.USA, 109, 2012
4CFQ
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CA-BOUND TRUNCATED (DELTA13C) AND C3S, C81S AND C86S MUTATED S100A4 COMPLEXED WITH NON-MUSCLE MYOSIN IIA
Descriptor:PROTEIN S100-A4, MYOSIN-9, CALCIUM ION
Authors:Duelli, A., Kiss, B., Lundholm, I., Bodor, A., Radnai, L., Petoukhov, M., Svergun, D., Nyitray, L., Katona, G.
Deposit date:2013-11-19
Release date:2014-05-07
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 Through Conformational Activation.
Plos One, 9, 2014
4CFR
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CA-BOUND S100A4 C3S, C81S, C86S AND F45W MUTANT COMPLEXED WITH NON- MUSCLE MYOSIN IIA
Descriptor:PROTEIN S100-A4, MYOSIN-9, CALCIUM ION
Authors:Duelli, A., Kiss, B., Lundholm, I., Bodor, A., Radnai, L., Petoukhov, M., Svergun, D., Nyitray, L., Katona, G.
Deposit date:2013-11-19
Release date:2014-05-07
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 Through Conformational Activation.
Plos One, 9, 2014
4D07
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DYNLL2 DYNEIN LIGHT CHAIN BINDS TO AN EXTENDED, UNSTRUCTURED LINEAR MOTIF OF MYOSIN 5A TAIL
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, MYOSIN VA VARIANT, ...
Authors:Bodor, A., Radnai, L., Hetenyi, C., Rapali, P., Lang, A., Kover, K.E., Perczel, A., Wahlgren, W.Y., Katona, G., Nyitray, L.
Deposit date:2014-04-24
Release date:2014-10-22
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity.
Biochemistry, 53, 2014
5LPU
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CRYSTAL STRUCTURE OF ANNEXIN A2 COMPLEXED WITH S100A4
Descriptor:Annexin A2, Protein S100-A4, CALCIUM ION, ...
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5LPX
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CRYSTAL STRUCTURE OF PKC PHOSPHORYLATION-MIMICKING MUTANT (S26E) ANNEXIN A2
Descriptor:Annexin A2, CALCIUM ION, GLYCEROL
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5LQ0
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CRYSTAL STRUCTURE OF TYR24 PHOSPHORYLATED ANNEXIN A2 AT 2.9 A RESOLUTION
Descriptor:Annexin A2, CALCIUM ION
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5LQ2
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CRYSTAL STRUCTURE OF TYR24 PHOSPHORYLATED ANNEXIN A2 AT 3.4 A RESOLUTION
Descriptor:Annexin A2, CALCIUM ION
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017