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1QDA
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CRYSTAL STRUCTURE OF EPIDOXORUBICIN-FORMALDEHYDE VIRTUAL CROSSLINK OF DNA
Descriptor:5' -D(CP*GP*CP*(G49)P*CP*GP)-3', 4'-EPIDOXORUBICIN
Authors:Podell, E.R., Harrington, D.J., Taatjes, D.J., Koch, T.H.
Deposit date:1999-05-17
Release date:1999-09-15
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
Acta Crystallogr.,Sect.D, 55, 1999
1GRZ
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A PREORGANIZED ACTIVE SITE IN THE CRYSTAL STRUCTURE OF THE TETRAHYMENA RIBOZYME
Descriptor:LSU R-RNA GROUP I INTRON
Authors:Golden, B.L., Gooding, A.R., Podell, E.R., Cech, T.R.
Deposit date:1998-09-14
Release date:1998-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (5 Å)
Cite:A preorganized active site in the crystal structure of the Tetrahymena ribozyme.
Science, 282, 1998
1QZG
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CRYSTAL STRUCTURE OF POT1 (PROTECTION OF TELOMERE)- SSDNA COMPLEX
Descriptor:telomeric single-stranded DNA, Protection of telomeres protein 1, THYMIDINE-5'-PHOSPHATE
Authors:Lei, M., Podell, E.R., Baumann, P., Cech, T.R.
Deposit date:2003-09-16
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Nature, 426, 2003
1QZH
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CRYSTAL STRUCTURE OF POT1 (PROTECTION OF TELOMERE)- SSDNA COMPLEX
Descriptor:telomeric single-stranded DNA, Protection of telomeres protein 1
Authors:Lei, M., Podell, E.R., Baumann, P., Cech, T.R.
Deposit date:2003-09-16
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA
Nature, 426, 2003
1XJV
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CRYSTAL STRUCTURE OF HUMAN POT1 BOUND TO TELOMERIC SINGLE-STRANDED DNA (TTAGGGTTAG)
Descriptor:hT10 d(TTAGGGTTAG), Protection of telomeres 1
Authors:Lei, M., Podell, E.R., Cech, T.R.
Deposit date:2004-09-25
Release date:2004-12-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
Nat.Struct.Mol.Biol., 11, 2004
2B2A
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CRYSTAL STRUCTURE OF THE TEN DOMAIN OF THE TELOMERASE REVERSE TRANSCRIPTASE
Descriptor:Telomerase reverse transcriptase
Authors:Jacobs, S.A., Podell, E.R., Cech, T.R.
Deposit date:2005-09-18
Release date:2006-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.
Nat.Struct.Mol.Biol., 13, 2006
2I46
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CRYSTAL STRUCTURE OF HUMAN TPP1
Descriptor:Adrenocortical dysplasia protein homolog
Authors:Wang, F., Podell, E.R., Zaug, A.J., Yang, Y.T., Baciu, P., Else, T., Hammer, G.D., Cech, T.R., Lei, M.
Deposit date:2006-08-21
Release date:2006-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The POT1-TPP1 telomere complex is a telomerase processivity factor.
Nature, 445, 2007
3KJO
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CRYSTAL STRUCTURE OF HPOT1V2-DTRUD(AGGGTTAG)
Descriptor:Protection of telomeres protein 1, DNA/RNA (5'-D(*T)-R(P*U)-D(P*AP*GP*GP*GP*TP*TP*AP*G)-3')
Authors:Nandakumar, J., Cech, T.R., Podell, E.R.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KJP
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CRYSTAL STRUCTURE OF HPOT1V2-GGTTAGGGTTAG
Descriptor:Protection of telomeres protein 1, 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'
Authors:Nandakumar, J., Cech, T.R., Podell, E.R.
Deposit date:2009-11-03
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
1HR2
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CRYSTAL STRUCTURE ANALYSIS OF A MUTANT P4-P6 DOMAIN (DELC209) OF TETRAHYMENA THEMOPHILA GROUP I INTRON.
Descriptor:P4-P6 DELC209 MUTANT RNA RIBOZYME DOMAIN, MAGNESIUM ION
Authors:Juneau, K., Podell, E.R., Harrington, D.J., Cech, T.R.
Deposit date:2000-12-20
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA--solvent interactions.
Structure, 9, 2001