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4W6B
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CRYSTAL STRUCTURE OF A SUPERFOLDER GFP MUTANT K26C DISULFIDE DIMER, P 21 21 21 SPACE GROUP
Descriptor:fluorescent protein K26C, MAGNESIUM ION, CHLORIDE ION
Authors:Pashkov, I., Sawaya, M.R., Leibly, D.J., Waldo, G.S., Yeates, T.O.
Deposit date:2014-08-20
Release date:2015-02-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
1SIX
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MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND ALPHA,BETA-IMIDO-DUTP
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Sawaya, M.R., Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.-S., Kim, M., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Yeates, T.O., Perry, J.L., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-03-01
Release date:2004-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
1SJN
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MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND ALPHA,BETA-IMIDO-DUTP
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ...
Authors:Sawaya, M.R., Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.S., Kim, M.-Y., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Yeates, T.O., Perry, J.L., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-03-04
Release date:2004-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
1SLH
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MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND DUDP
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, DEOXYURIDINE-5'-DIPHOSPHATE, ...
Authors:Sawaya, M.R., Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.S., Kim, M.-Y., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Yeates, T.O., Perry, J.L., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-03-05
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
1SM8
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M. TUBERCULOSIS DUTPASE COMPLEXED WITH CHROMIUM AND DUTP
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, CHROMIUM ION, NITRATE ION, ...
Authors:Sawaya, M.R., Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.S., Kim, M.-Y., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Yeates, T.O., Perry, J.L., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-03-08
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
1SMC
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MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH DUTP IN THE ABSENCE OF METAL ION.
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, DEOXYURIDINE-5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Sawaya, M.R., Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.S., Kim, M.-Y., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Yeates, T.O., Perry, J.L., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-03-09
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
1SNF
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MYCOBACTERIUM TUBERCULOSIS DUTPASE COMPLEXED WITH MAGNESIUM AND DEOXYURIDINE 5'-MONOPHOSPHATE
Descriptor:Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, NITRATE ION, ...
Authors:Sawaya, M.R., Chan, S., Segelke, B., Lekin, T., Krupka, H., Cho, U.S., Kim, M.-Y., So, M., Kim, C.-Y., Naranjo, C.M., Rogers, Y.C., Park, M.S., Waldo, G.S., Pashkov, I., Cascio, D., Yeates, T.O., Perry, J.L., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-03-10
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
1SVD
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THE STRUCTURE OF HALOTHIOBACILLUS NEAPOLITANUS RUBISCO
Descriptor:ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, Ribulose bisphosphate carboxylase small chain, SULFATE ION, ...
Authors:Kerfeld, C.A., Sawaya, M.R., Pashkov, I., Cannon, G., Williams, E., Tran, K., Yeates, T.O.
Deposit date:2004-03-29
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of Halothiobacillus neapolitanus RuBisCo
To be Published
2GM8
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TENA HOMOLOG/THI-4 THIAMINASE COMPLEXED WITH PRODUCT 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE
Descriptor:tenA homolog/Thi-4 Thiaminase, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, 1,2-ETHANEDIOL
Authors:Sawaya, M.R., Chan, S., Han, G.W., Perry, L.J., Pashkov, I.
Deposit date:2006-04-06
Release date:2006-04-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a TenA Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum
To be Published
2Q1N
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ACTIN DIMER CROSS-LINKED BETWEEN RESIDUES 41 AND 374
Descriptor:Actin, alpha skeletal muscle, CALCIUM ION, ...
Authors:Sawaya, M.R., Pashkov, I., Kudryashov, D.S., Adisetiyo, H., Reisler, E., Yeates, T.O.
Deposit date:2007-05-25
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Multiple crystal structures of actin dimers and their implications for interactions in the actin filament.
Acta Crystallogr.,Sect.D, 64, 2008
2Q31
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ACTIN DIMER CROSS-LINKED BETWEEN RESIDUES 41 AND 374 AND PROTEOLYTICALLY CLEAVED BY SUBTILISIN BETWEEN RESIDUES 47 AND 48.
Descriptor:Actin, alpha skeletal muscle, CALCIUM ION, ...
Authors:Sawaya, M.R., Pashkov, I., Kudryashov, D.S., Reisler, E., Yeates, T.O.
Deposit date:2007-05-29
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Multiple crystal structures of actin dimers and their implications for interactions in the actin filament.
Acta Crystallogr.,Sect.D, 64, 2008
2Q36
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ACTIN DIMER CROSS-LINKED BETWEEN RESIDUES 191 AND 374 AND COMPLEXED WITH KABIRAMIDE C
Descriptor:Actin, alpha skeletal muscle, CALCIUM ION, ...
Authors:Sawaya, M.R., Pashkov, I., Kudryashov, D.S., Reisler, E., Yeates, T.O.
Deposit date:2007-05-29
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multiple crystal structures of actin dimers and their implications for interactions in the actin filament.
Acta Crystallogr.,Sect.D, 64, 2008
3CJB
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ACTIN DIMER CROSS-LINKED BY V. CHOLERAE MARTX TOXIN AND COMPLEXED WITH GELSOLIN-SEGMENT 1
Descriptor:Actin, alpha skeletal muscle, Gelsolin, ...
Authors:Sawaya, M.R., Kudryashov, D.S., Pashkov, I., Reisler, E., Yeates, T.O.
Deposit date:2008-03-12
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.
Proc.Natl.Acad.Sci.USA, 105, 2008
3CJC
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ACTIN DIMER CROSS-LINKED BY V. CHOLERAE MARTX TOXIN AND COMPLEXED WITH DNASE I AND GELSOLIN-SEGMENT 1
Descriptor:Actin, alpha skeletal muscle, Deoxyribonuclease-1, ...
Authors:Sawaya, M.R., Kudryashov, D.S., Pashkov, I., Reisler, E., Yeates, T.O.
Deposit date:2008-03-12
Release date:2008-03-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.
Proc.Natl.Acad.Sci.USA, 105, 2008
3HL9
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SIMVASTATIN SYNTHASE (LOVD) FROM ASPERGILLUS TERREUS, UNLIGANDED
Descriptor:Transesterase
Authors:Sawaya, M.R., Yeates, T.O., Laidman, J., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
3HLB
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SIMVASTATIN SYNTHASE (LOVD) FROM ASPERGILLUS TERREUS, UNLIGANDED, SELENOMETHIONYL DERIVATIVE
Descriptor:Transesterase, SULFATE ION
Authors:Sawaya, M.R., Yeates, T.O., Laidman, J., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
3HLC
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SIMVASTATIN SYNTHASE (LOVD) FROM ASPERGILLUS TERREUS, S5 MUTANT, UNLIGANDED
Descriptor:Transesterase, GLYCEROL, TETRAETHYLENE GLYCOL
Authors:Sawaya, M.R., Yeates, T.O., Laidman, J., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
3HLD
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SIMVASTATIN SYNTHASE (LOVD), FROM ASPERGILLUS TERREUS, S5 MUTANT COMPLEX WITH MONACOLIN J ACID
Descriptor:Transesterase, (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, FORMIC ACID
Authors:Sawaya, M.R., Yeates, T.O., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
3HLE
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SIMVASTATIN SYNTHASE (LOVD), FROM ASPERGILLUS TERREUS, S5 MUTANT, S76A MUTANT, COMPLEX WITH MONACOLIN J ACID
Descriptor:Transesterase, (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Sawaya, M.R., Yeates, T.O., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
3HLF
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SIMVASTATIN SYNTHASE (LOVD), FROM ASPERGILLUS TERREUS, S5 MUTANT, S76A MUTANT, COMPLEX WITH SIMVASTATIN
Descriptor:Transesterase, Simvastatin acid
Authors:Sawaya, M.R., Yeates, T.O., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
3HLG
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SIMVASTATIN SYNTHASE (LOVD), FROM ASPERGILLUS TERREUS, S5 MUTANT, S76A MUTANT, COMPLEX WITH LOVASTATIN
Descriptor:Transesterase, (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID
Authors:Sawaya, M.R., Yeates, T.O., Pashkov, I., Gao, X., Tang, Y.
Deposit date:2009-05-27
Release date:2009-10-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Directed evolution and structural characterization of a simvastatin synthase
Chem.Biol., 16, 2009
1RII
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CRYSTAL STRUCTURE OF PHOSPHOGLYCERATE MUTASE FROM M. TUBERCULOSIS
Descriptor:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, GLYCEROL
Authors:Mueller, P., Sawaya, M.R., Chan, S., Wu, Y., Pashkova, I., Perry, J., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-11-17
Release date:2004-10-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase.
Acta Crystallogr.,Sect.D, 61, 2005
1MQ7
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CRYSTAL STRUCTURE OF DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS (RV2697C)
Descriptor:DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Sawaya, M.R., Chan, S., Segelke, B.W., Lekin, T., Heike, K., Cho, U.S., Naranjo, C., Perry, L.J., Yeates, T.O., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-09-13
Release date:2002-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism.
J.Mol.Biol., 341, 2004
3SKV
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SALICYLYL-ACYLTRANSFERASE SSFX3 FROM A TETRACYCLINE BIOSYNTHETIC PATHWAY
Descriptor:SsfX3, GLYCEROL
Authors:Pickens, L.B., Sawaya, M.R., Yeates, T.O., Tang, Y.
Deposit date:2011-06-23
Release date:2011-10-05
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural and Biochemical Characterization of the Salicylyl-acyltranferase SsfX3 from a Tetracycline Biosynthetic Pathway.
J.Biol.Chem., 286, 2011
4W69
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CRYSTAL STRUCTURE OF FULL-LENGTH SPLIT GFP MUTANT Q157C DISULFIDE DIMER, P 43 21 2 SPACE GROUP
Descriptor:fluorescent protein Q157C
Authors:Leibly, D.J., Waldo, G.S., Yeates, T.O.
Deposit date:2014-08-20
Release date:2015-02-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.975 Å)
Cite:A Suite of Engineered GFP Molecules for Oligomeric Scaffolding.
Structure, 23, 2015
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