Author results

1HIJ
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INTERLEUKIN-4 MUTANT WITH ARG 88 REPLACED WITH GLN (R88Q)
Descriptor:INTERLEUKIN-4
Authors:Mueller, T., Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1HIK
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INTERLEUKIN-4 (WILD-TYPE)
Descriptor:INTERLEUKIN-4
Authors:Mueller, T., Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1CYL
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ASPECTS OF RECEPTOR BINDING AND SIGNALLING OF INTERLEUKIN-4 INVESTIGATED BY SITE-DIRECTED MUTAGENESIS AND NMR SPECTROSCOPY
Descriptor:INTERLEUKIN-4
Authors:Mueller, T., Sebald, W., Oschkinat, H.
Deposit date:1994-02-21
Release date:1994-09-30
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy.
J.Mol.Biol., 237, 1994
2CYK
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ASPECTS OF RECEPTOR BINDING AND SIGNALLING OF INTERLEUKIN-4 INVESTIGATED BY SITE-DIRECTED MUTAGENESIS AND NMR SPECTROSCOPY
Descriptor:INTERLEUKIN-4
Authors:Mueller, T., Sebald, W., Oschkinat, H.
Deposit date:1994-08-16
Release date:1994-12-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy.
J.Mol.Biol., 237, 1994
5O74
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CRYSTAL STRUCTURE OF HUMAN RAB1B COVALENTLY BOUND TO THE GEF DOMAIN OF DRRA/SIDM FROM LEGIONELLA PNEUMOPHILA IN THE PRESENCE OF GDP
Descriptor:Multifunctional virulence effector protein DrrA, Ras-related protein Rab-1B, GUANOSINE-5'-DIPHOSPHATE
Authors:Cigler, M., Mueller, T., Horn-Ghetko, D., von Wrisberg, M.K., Fottner, M., Goody, R.S., Itzen, A., Mueller, M.P., Lang, K.
Deposit date:2017-06-08
Release date:2017-10-11
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Proximity-Triggered Covalent Stabilization of Low-Affinity Protein Complexes In Vitro and In Vivo.
Angew. Chem. Int. Ed. Engl., 56, 2017
5ARF
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SMYD2 IN COMPLEX WITH SMALL MOLECULE INHIBITOR COMPOUND-2
Descriptor:N-LYSINE METHYLTRANSFERASE SMYD2, N-[3-(4-CHLOROPHENYL)-1-{N'-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL}-4,5-DIHYDRO-1H- PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE, S-ADENOSYLMETHIONINE, ...
Authors:Hillig, R.C., Badock, V., Barak, N., Stellfeld, T., Eggert, E., ter Laak, A., Weiske, J., Christ, C.D., Koehr, S., Stoeckigt, D., Mowat, J., Mueller, T., Fernandez-Montalvan, A.E., Hartung, I.V., Stresemann, C., Brumby, T., Weinmann, H.
Deposit date:2015-09-24
Release date:2016-04-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (Bay-598) for the Protein Lysine Methyltransferase Smyd2.
J.Med.Chem., 59, 2016
5ARG
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SMYD2 IN COMPLEX WITH SGC PROBE BAY-598
Descriptor:N-LYSINE METHYLTRANSFERASE SMYD2, ZINC ION, N-[1-(N'-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL)-3-(3,4-DICHLOROPHENYL)-4,5-DIHYDRO-1H-PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE, ...
Authors:Hillig, R.C., Badock, V., Barak, N., Stellfeld, T., Eggert, E., ter Laak, A., Weiske, J., Christ, C.D., Koehr, S., Stoeckigt, D., Mowat, J., Mueller, T., Fernandez-Montalvan, A.E., Hartung, I.V., Stresemann, C., Brumby, T., Weinmann, H.
Deposit date:2015-09-24
Release date:2016-04-27
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Discovery and Characterization of a Highly Potent and Selective Aminopyrazoline-Based in Vivo Probe (Bay-598) for the Protein Lysine Methyltransferase Smyd2.
J.Med.Chem., 59, 2016
2K3G
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NMR STRUCTURE ANALYSIS OF A BMP RECEPTOR
Descriptor:Bone morphogenetic protein receptor type-1A
Authors:Klages, J., Kotzsch, A., Mueller, T., Kessler, H.
Deposit date:2008-05-07
Release date:2008-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
Biochemistry, 47, 2008
4QGK
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STRUCTURE OF THE HUMAN SJOGREN LARSSON SYNDROME ENZYME FATTY ALDEHYDE DEHYDROGENASE (FALDH)
Descriptor:Fatty aldehyde dehydrogenase
Authors:Zander, U., Keller, M., Marquez, J.A.
Deposit date:2014-05-23
Release date:2014-07-30
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A gatekeeper helix determines the substrate specificity of Sjogren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase.
Nat Commun, 5, 2014
5OR2
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CRYSTAL STRUCTURES OF PYR1/HAB1 IN COMPLEX WITH SYNTHETIC ANALOGUES OF ABSCISIC ACID
Descriptor:Abscisic acid receptor PYR1, Protein phosphatase 2C 16, (2~{Z},4~{E})-3-cyclopropyl-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]penta-2,4-dienoic acid, ...
Authors:Freigang, J.
Deposit date:2017-08-15
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses
Eur.J.Org.Chem., 2018
5OR6
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CRYSTAL STRUCTURES OF PYR1/HAB1 IN COMPLEX WITH SYNTHETIC ANALOGUES OF ABSCISIC ACID
Descriptor:Abscisic acid receptor PYR1, Protein phosphatase 2C 16, (~{E})-3-(trifluoromethyl)-5-[(1~{S})-2,6,6-trimethyl-1-oxidanyl-4-oxidanylidene-cyclohex-2-en-1-yl]pent-2-en-4-ynoic acid, ...
Authors:Freigang, J.
Deposit date:2017-08-15
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into the in Vitro and in Vivo SAR of Abscisic Acid - Exploring Unprecedented Variations of the Side Chain via Cross-Coupling-Mediated Syntheses
Eur.J.Org.Chem., 2018