Author results

2HUR
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ESCHERICHIA COLI NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION
Authors:Moynie, L., Giraud, M.-F., Georgescauld, F., Lascu, I., Dautant, A.
Deposit date:2006-07-27
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family
Proteins, 67, 2007
2JKY
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SACCHAROMYCES CEREVISIAE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH GMP (GUANOSINE 5'- MONOPHOSPHATE) (TETRAGONAL CRYSTAL FORM)
Descriptor:HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION, ...
Authors:Moynie, L., Giraud, M.F., Breton, A., Boissier, F., Daignan-Fornier, B., Dautant, A.
Deposit date:2008-09-02
Release date:2009-11-17
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Protein Sci., 21, 2012
2JKZ
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SACCHAROMYCES CEREVISIAE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH GMP (GUANOSINE 5'- MONOPHOSPHATE) (ORTHORHOMBIC CRYSTAL FORM)
Descriptor:HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, GUANOSINE-5'-MONOPHOSPHATE, SULFATE ION
Authors:Moynie, L., Giraud, M.F., Breton, A., Boissier, F., Daignan-Fornier, B., Dautant, A.
Deposit date:2008-09-02
Release date:2009-11-17
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Protein Sci., 21, 2012
2XBU
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SACCHAROMYCES CEREVISIAE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH GMP (MONOCLINIC CRYSTAL FORM)
Descriptor:HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ACETATE ION, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Moynie, L., Giraud, M.F., Breton, A., Boissier, F., Daignan-Fornier, B., Dautant, A.
Deposit date:2010-04-15
Release date:2011-05-04
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Protein Sci., 21, 2012
4AVY
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THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY.
Descriptor:PROBABLE SHORT-CHAIN DEHYDROGENASE
Authors:Moynie, L., McMahon, S.A., Alphey, M.S., Liu, H., Duthie, F., Naismith, J.H.
Deposit date:2012-05-30
Release date:2012-12-12
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4B0B
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 3-(PYRIDIN-2-YLOXY)ANILINE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, 3-(pyridin-2-yloxy)aniline
Authors:Moynie, L., McMahon, S.A., Duthie, F.G., Taylor, J.W., Naismith, J.H.
Deposit date:2012-07-01
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonasaeruginosa.
J.Mol.Biol., 425, 2013
4B0C
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 3-(PENTYLTHIO)-4H-1,2,4-TRIAZOLE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, 5-(pentylsulfanyl)-1H-1,2,4-triazole
Authors:Moynie, L., McMahon, S.A., Duthie, F.G., Naismith, J.H.
Deposit date:2012-07-01
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonasaeruginosa.
J.Mol.Biol., 425, 2013
4B0I
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) MUTANT (H70N) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 3-HYDROXYDECANOYL-N-ACETYL CYSTEAMINE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, S-[2-(acetylamino)ethyl] (3R)-3-hydroxydecanethioate
Authors:Moynie, L., McMahon, S.A., Leckie, S.M., Duthie, F.G., Koehnke, A., Naismith, J.H.
Deposit date:2012-07-02
Release date:2012-11-28
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonas Aeruginosa
J.Mol.Biol., 425, 2013
4B0J
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH 5-(2- THIENYL)-3-ISOXAZOLYL METHANOL
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, (5-thiophen-2-ylisoxazol-3-yl)methanol
Authors:Moynie, L., McMahon, S.A., Duthie, F.G., Naismith, J.H.
Deposit date:2012-07-02
Release date:2012-11-28
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonas Aeruginosa
J.Mol.Biol., 425, 2013
4B79
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THE AEROPATH PROJECT AND PSEUDOMONAS AERUGINOSA HIGH-THROUGHPUT CRYSTALLOGRAPHIC STUDIES FOR ASSESSMENT OF POTENTIAL TARGETS IN EARLY STAGE DRUG DISCOVERY.
Descriptor:PROBABLE SHORT-CHAIN DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Moynie, L., McMahon, S.A., Alphey, M.S., Liu, H., Duthie, F., Naismith, J.H.
Deposit date:2012-08-16
Release date:2012-08-29
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery
Acta Crystallogr.,Sect.F, 69, 2013
4B8U
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH N- ISOBUTYL-2-(5-(2-THIENYL)-1,2-OXAZOL-3-YL-)METHOXY)ACETAMIDE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, N-isobutyl-2-{[5-(thiophen-2-yl)-1,2-oxazol-3-yl]methoxy}acetamide, SULFATE ION
Authors:Moynie, L., McMahon, S.A., Duthie, F.G., Brenk, R., Naismith, J.H.
Deposit date:2012-08-30
Release date:2012-09-26
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural Insights Into the Mechanism and Inhibition of the Beta-Hydroxydecanoyl-Acyl Carrier Protein Dehydratase from Pseudomonasaeruginosa.
J.Mol.Biol., 425, 2013
4CL6
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH N-(4- CHLOROBENZYL)-3-(2-FURYL)-1H-1,2,4-TRIAZOL-5-AMINE
Descriptor:3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, N-(4-chlorobenzyl)-5-(furan-2-yl)-1H-1,2,4-triazol-3-amine
Authors:Moynie, L., McMahon, S.A., Duthie, F.G., Naismith, J.H.
Deposit date:2014-01-13
Release date:2015-01-21
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:A Substrate Mimic Allows High Throughput Assay of the Faba Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas Aeruginosa Faba.
J.Mol.Biol., 428, 2016
4FQ9
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CRYSTAL STRUCTURE OF 3-HYDROXYDECANOYL-ACYL CARRIER PROTEIN DEHYDRATASE (FABA) FROM PSEUDOMONAS AERUGINOSA
Descriptor:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, PHOSPHATE ION, GLYCEROL
Authors:Moynie, L., Mcmahon, S.A., Duthie, F.G., Naismith, J.H.
Deposit date:2012-06-25
Release date:2013-03-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa
J.Mol.Biol., 425, 2013
5FOK
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CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIUA FROM PSEUDOMONAS AERUGINOSA
Descriptor:IRON TRANSPORT OUTER MEMBRANE RECEPTOR, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SODIUM ION, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2015-11-23
Release date:2016-05-11
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob. Agents Chemother., 61, 2017
5FP1
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CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIUA FROM ACINETOBACTER BAUMANNII
Descriptor:TONB-DEPENDENT SIDEROPHORE RECEPTOR, PHOSPHATE ION, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Moynie, L., Tortajada, A., Naismith, J.H.
Deposit date:2015-11-26
Release date:2016-05-11
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob. Agents Chemother., 61, 2017
5FP2
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CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIRA FROM PSEUDOMONAS AERUGINOSA
Descriptor:FERRIC ENTEROBACTIN RECEPTOR PIRA, N-OCTANE, SULFATE ION
Authors:Moynie, L., Tortajada, A., Naismith, J.H.
Deposit date:2015-11-27
Release date:2015-12-09
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob. Agents Chemother., 61, 2017
5FR8
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CRYSTAL STRUCTURE OF THE SIDEROPHORE RECEPTOR PIRA FROM ACINETOBACTER BAUMANNII
Descriptor:TONB-DEPENDENT SIDEROPHORE RECEPTOR, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Moynie, L., Tortajada, A., Naismith, J.H.
Deposit date:2015-12-16
Release date:2016-05-11
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
Antimicrob. Agents Chemother., 61, 2017
5M9B
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ferric enterobactin receptor, ACETIC ACID, 1,2-ETHANEDIOL
Authors:Moynie, L., Naismith, J.H.
Deposit date:2016-11-01
Release date:2018-02-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa
To Be Published
5MZS
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) MUTANT (R480A_Q482A) FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ferric enterobactin receptor
Authors:Moynie, L., Naismith, J.H.
Deposit date:2017-02-01
Release date:2018-02-14
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) mutant (R480A_Q482A) from Pseudomonas aeruginosa
To Be Published
5NC3
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH THE TRIS-CATECHOL VECTOR
Descriptor:Ferric enterobactin receptor, FE (III) ION, ~{N}-[2-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-3-(prop-2-ynylamino)propyl]amino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide
Authors:Moynie, L., Naismith, J.H.
Deposit date:2017-03-03
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa in complex with the Tris-catechol vector
To Be Published
5NC4
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) IN COMPLEX WITH PROTOCHELIN FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ferric enterobactin receptor, FE (III) ION, ~{N}-[(5~{S})-5-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-6-[4-[[2,3-bis(oxidanyl)phenyl]carbonylamino]butylamino]-6-oxidanylidene-hexyl]-2,3-bis(oxidanyl)benzamide
Authors:Moynie, L., Naismith, J.H.
Deposit date:2017-03-03
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) mutant (R480A_Q482A) from Pseudomonas aeruginosa
To Be Published
5NR2
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AZOTOCHELIN
Descriptor:Ferric enterobactin receptor, FE (III) ION, Azotochelin, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2017-04-21
Release date:2018-05-16
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa in complex with Azotochelin
To Be Published
5OUT
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CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) MUTANT (G324V) FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ferric enterobactin receptor
Authors:Moynie, L., Naismith, J.H.
Deposit date:2017-08-24
Release date:2018-09-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:CRYSTAL STRUCTURE OF THE FERRIC ENTEROBACTIN RECEPTOR (PFEA) MUTANT (G324V) FROM PSEUDOMONAS AERUGINOSA
To Be Published
6H7F
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CRYSTAL STRUCTURE OF BAUA, THE FERRIC PREACINETOBACTIN RECEPTOR FROM ACINETOBACTER BAUMANNII IN COMPLEX WITH FE3+-PREACINETOBACTIN-ACINETOBACTIN
Descriptor:BauA, FE (III) ION, (4~{S},5~{R})-2-[2,3-bis(oxidanyl)phenyl]-~{N}-[2-(1~{H}-imidazol-4-yl)ethyl]-5-methyl-~{N}-oxidanyl-4,5-dihydro-1,3-oxazole-4-carboxamide, ...
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-07-31
Release date:2018-10-10
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogenAcinetobacter baumannii.
Elife, 7, 2018
6H7V
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CRYSTAL STRUCTURE OF BAUA, THE FERRIC PREACINETOBACTIN RECEPTOR FROM ACINETOBACTER BAUMANNII
Descriptor:Ligand-gated channel protein, 1,2-ETHANEDIOL, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Moynie, L., Naismith, J.H.
Deposit date:2018-07-31
Release date:2018-10-10
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogenAcinetobacter baumannii.
Elife, 7, 2018