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1UWQ
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS
分子名称:BETA-GALACTOSIDASE, ACETATE ION
著者Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
登録日2004-02-11
公開日2004-05-20
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
1UWR
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH 2-DEOXY-2-FLUORO-GALACTOSE
分子名称:BETA-GALACTOSIDASE, 2-DEOXY-2-FLUORO-ALPHA-D-GALACTOPYRANOSE, ACETATE ION
著者Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
登録日2004-02-11
公開日2004-05-20
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural Studies of the Beta-Glycosidase from Sulfolobus Solfataricus in Complex with Covalently and Noncovalently Bound Inhibitors.
Biochemistry, 43, 2004
1UWS
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH 2-DEOXY-2-FLUORO-GLUCOSE
分子名称:BETA-GALACTOSIDASE, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ACETATE ION
著者Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
登録日2004-02-11
公開日2004-05-20
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
1UWT
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH D-GALACTOHYDROXIMO-1,5-LACTAM
分子名称:BETA-GALACTOSIDASE, (2E,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)-2-PIPERIDINONE, ACETATE ION
著者Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
登録日2004-02-11
公開日2004-05-20
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
1UWU
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STRUCTURE OF BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH D-GLUCOHYDROXIMO-1,5-LACTAM
分子名称:BETA-GALACTOSIDASE, (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, ACETATE ION
著者Gloster, T.M., Roberts, S., Ducros, V.M.-A., Perugino, G., Rossi, M., Hoos, R., Moracci, M., Vasella, A., Davies, G.J.
登録日2004-02-11
公開日2004-05-20
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors.
Biochemistry, 43, 2004
2CEQ
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BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH GLUCOIMIDAZOLE
分子名称:BETA-GALACTOSIDASE, ACETATE ION, GLUCOIMIDAZOLE
著者Gloster, T.M., Moracci, M., Vasella, A., Davies, G.J.
登録日2006-02-10
公開日2006-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
2CER
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BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH PHENETHYL-SUBSTITUTED GLUCOIMIDAZOLE
分子名称:BETA-GLUCOSIDASE A, (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ACETATE ION
著者Gloster, T.M., Roberts, S., Moracci, M., Vasella, A., Davies, G.J.
登録日2006-02-10
公開日2006-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
2WSP
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THERMOTOGA MARITIMA ALPHA-L-FUCOSYNTHASE, TMD224G, IN COMPLEX WITH ALPHA-L-FUC-(1-2)-BETA-L-FUC-N3
分子名称:ALPHA-L-FUCOSIDASE, PUTATIVE, ALPHA-L-FUCOSE, ...
著者Sulzenbacher, G., Lipski, A., Cobucci-Ponzano, B., Conte, F., Bedini, E., Corsaro, M.M., Parrilli, M., Dal Piaz, F., Lepore, L., Rossi, M., Moracci, M.
登録日2009-09-08
公開日2010-01-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Beta-Glycosyl Azides as Substrates for Alpha-Glycosynthases: Preparation of Novel Efficient Alpha-L-Fucosynthases
Chem.Biol., 16, 2009
1COA
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THE EFFECT OF CAVITY CREATING MUTATIONS IN THE HYDROPHOBIC CORE OF CHYMOTRYPSIN INHIBITOR 2
分子名称:CHYMOTRYPSIN INHIBITOR 2
著者Jackson, S.E., Moracci, M., Elmasry, N., Johnson, C.M., Fersht, A.R.
登録日1993-05-14
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2.
Biochemistry, 32, 1993
5NN3
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CRYSTAL STRUCTURE OF HUMAN LYSOSOMAL ACID-ALPHA-GLUCOSIDASE, GAA
分子名称:Lysosomal alpha-glucosidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Roig-Zamboni, V., Cobucci-Ponzano, B., Iacono, R., Ferrara, M.C., Germany, S., Parenti, G., Bourne, Y., Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
5NN4
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CRYSTAL STRUCTURE OF HUMAN LYSOSOMAL ACID-ALPHA-GLUCOSIDASE, GAA, IN COMPLEX WITH N-ACETYL-CYSTEINE
分子名称:Lysosomal alpha-glucosidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Roig-Zamboni, V., Cobucci-Ponzano, B., Iacono, R., Ferrara, M.C., Germany, S., Parenti, G., Bourne, Y., Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
5NN5
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CRYSTAL STRUCTURE OF HUMAN LYSOSOMAL ACID-ALPHA-GLUCOSIDASE, GAA, IN COMPLEX WITH 1-DEOXYNOJIRIMYCIN
分子名称:Lysosomal alpha-glucosidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Roig-Zamboni, V., Cobucci-Ponzano, B., Iacono, R., Ferrara, M.C., Germany, S., Parenti, G., Bourne, Y., Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
5NN6
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CRYSTAL STRUCTURE OF HUMAN LYSOSOMAL ACID-ALPHA-GLUCOSIDASE, GAA, IN COMPLEX WITH N-HYDROXYETHYL-1-DEOXYNOJIRIMYCIN
分子名称:Lysosomal alpha-glucosidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Roig-Zamboni, V., Cobucci-Ponzano, B., Iacono, R., Ferrara, M.C., Germany, S., Parenti, G., Bourne, Y., Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
5NN8
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CRYSTAL STRUCTURE OF HUMAN LYSOSOMAL ACID-ALPHA-GLUCOSIDASE, GAA, IN COMPLEX WITH ACARBOSE
分子名称:Lysosomal alpha-glucosidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Roig-Zamboni, V., Cobucci-Ponzano, B., Iacono, R., Ferrara, M.C., Germany, S., Parenti, G., Bourne, Y., Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
1GOW
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BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS
分子名称:BETA-GLYCOSIDASE
著者Pearl, L.H., Aguilar, C.F., Sanderson, I.
登録日1996-09-19
公開日1997-08-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the beta-glycosidase from the hyperthermophilic archeon Sulfolobus solfataricus: resilience as a key factor in thermostability.
J.Mol.Biol., 271, 1997
2CES
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BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH GLUCOIMIDAZOLE
分子名称:BETA-GLUCOSIDASE A, ACETATE ION, GLUCOIMIDAZOLE, ...
著者Gloster, T.M., Roberts, S., Vasella, A., Davies, G.J.
登録日2006-02-10
公開日2006-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
2CET
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BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH PHENETHYL- SUBSTITUTED GLUCOIMIDAZOLE
分子名称:BETA-GLUCOSIDASE A, ACETATE ION, (5R,6R,7S,8S)-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ...
著者Gloster, T.M., Roberts, S., Vasella, A., Davies, G.J.
登録日2006-02-10
公開日2006-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors.
Biochemistry, 45, 2006
5IK4
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LAMININ A2LG45 C-FORM, APO.
分子名称:Laminin subunit alpha-2, CALCIUM ION, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
著者Briggs, D.C., Hohenester, E., Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2016-09-28
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK5
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LAMININ A2LG45 C-FORM, G6/7 BOUND.
分子名称:Laminin subunit alpha-2, CALCIUM ION, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, ...
著者Briggs, D.C., Hohenester, E., Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2016-09-28
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK7
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LAMININ A2LG45 I-FORM, APO.
分子名称:Laminin subunit alpha-2, CALCIUM ION, CITRATE ANION, ...
著者Briggs, D.C., Hohenester, E., Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016
5IK8
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LAMININ A2LG45 I-FORM, G6/7 BOUND.
分子名称:Laminin subunit alpha-2, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Briggs, D.C., Hohenester, E., Campbell, K.P.
登録日2016-03-03
公開日2016-08-10
最終更新日2016-09-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of laminin binding to the LARGE glycans on dystroglycan.
Nat.Chem.Biol., 12, 2016