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1BW0
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CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE FROM TRYPANOSOMA CRUZI
分子名称:PROTEIN (TYROSINE AMINOTRANSFERASE)
著者Blankenfeldt, W., Montemartini, M., Hunter, G.R., Kalisz, H.M., Nowicki, C., Hecht, H.J.
登録日1998-09-28
公開日1999-09-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode.
Protein Sci., 8, 1999
1FG4
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STRUCTURE OF TRYPAREDOXIN II
分子名称:TRYPAREDOXIN II
著者Hofmann, B., Budde, H., Bruns, K., Guerrero, S.A., Kalisz, H.M., Menge, U., Montemartini, M., Nogoceke, E., Steinert, P., Wissing, J.B., Flohe, L., Hecht, H.J.
登録日2000-07-28
公開日2001-04-25
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001
4BZN
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CRYSTAL STRUCTURE OF PIM1 IN COMPLEX WITH A PYRROLO(1,2-A)PYRAZINONE INHIBITOR
分子名称:SERINE/THREONINE-PROTEIN KINASE PIM-1, N-(2,2-dimethylpropyl)-2-[1-oxo-7-(thiophen-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide
著者Casale, E., Casuscelli, F., Ardini, E., Avanzi, N., Cervi, G., D'Anello, M., Donati, D., Faiardi, D., Ferguson, R.D., Fogliatto, G., Galvani, A., Marsiglio, A., Mirizzi, D.G., Montemartini, M., Orrenius, C., Papeo, G., Piutti, C., Salom, B., Felder, E.R.
登録日2013-07-29
公開日2013-10-30
最終更新日2013-11-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery and Optimization of Pyrrolo[1,2-A]Pyrazinones Leads to Novel and Selective Inhibitors of Pim Kinases.
Bioorg.Med.Chem., 21, 2013
4BZO
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CRYSTAL STRUCTURE OF PIM1 IN COMPLEX WITH A PYRROLO-PYRAZINONE INHIBITOR
分子名称:SERINE/THREONINE-PROTEIN KINASE PIM-1, N-[(1S)-2-AMINO-1-PHENYLETHYL]-2-[(4S)-7-(2-FLUORO-4-PYRIDINYL)-1-OXO-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZIN-4-YL]ACETAMIDE
著者Casale, E., Casuscelli, F., Ardini, E., Avanzi, N., Cervi, G., D'Anello, M., Donati, D., Faiardi, D., Ferguson, R.D., Fogliatto, G., Galvani, A., Marsiglio, A., Mirizzi, D.G., Montemartini, M., Orrenius, C., Papeo, G., Piutti, C., Salom, B., Felder, E.R.
登録日2013-07-29
公開日2013-10-30
最終更新日2013-11-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery and Optimization of Pyrrolo[1,2-A]Pyrazinones Leads to Novel and Selective Inhibitors of Pim Kinases.
Bioorg.Med.Chem., 21, 2013
1EWX
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CRYSTAL STRUCTURE OF NATIVE TRYPAREDOXIN I FROM CRITHIDIA FASCICULATA
分子名称:TRYPAREDOXIN I
著者Hofmann, B., Guerrero, S.A., Kalisz, H.M., Menge, U., Nogoceke, E., Montemartini, M., Singh, M., Flohe, L., Hecht, H.J.
登録日2000-04-28
公開日2000-05-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001
1EZK
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CRYSTAL STRUCTURE OF RECOMBINANT TRYPAREDOXIN I
分子名称:TRYPAREDOXIN I
著者Hofmann, B., Guerrero, S.A., Kalisz, H.M., Menge, U., Nogoceke, E., Montemartini, M., Singh, M., Flohe, L., Hecht, H.J.
登録日2000-05-11
公開日2000-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001
1I5G
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TRYPAREDOXIN II COMPLEXED WITH GLUTATHIONYLSPERMIDINE
分子名称:TRYPAREDOXIN II, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTATHIONYLSPERMIDINE
著者Hofmann, B., Budde, H., Bruns, K., Guerrero, S.A., Kalisz, H.M., Menge, U., Montemartini, M., Nogoceke, E., Steinert, P., Wissing, J.B., Flohe, L., Hecht, H.-J.
登録日2001-02-27
公開日2001-03-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001