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1BW0
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CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE FROM TRYPANOSOMA CRUZI
Descriptor:PROTEIN (TYROSINE AMINOTRANSFERASE)
Authors:Blankenfeldt, W., Montemartini, M., Hunter, G.R., Kalisz, H.M., Nowicki, C., Hecht, H.J.
Deposit date:1998-09-28
Release date:1999-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode.
Protein Sci., 8, 1999
1FG4
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STRUCTURE OF TRYPAREDOXIN II
Descriptor:TRYPAREDOXIN II
Authors:Hofmann, B., Budde, H., Bruns, K., Guerrero, S.A., Kalisz, H.M., Menge, U., Montemartini, M., Nogoceke, E., Steinert, P., Wissing, J.B., Flohe, L., Hecht, H.J.
Deposit date:2000-07-28
Release date:2001-04-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001
4BZN
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CRYSTAL STRUCTURE OF PIM1 IN COMPLEX WITH A PYRROLO(1,2-A)PYRAZINONE INHIBITOR
Descriptor:SERINE/THREONINE-PROTEIN KINASE PIM-1, N-(2,2-dimethylpropyl)-2-[1-oxo-7-(thiophen-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl]acetamide
Authors:Casale, E., Casuscelli, F., Ardini, E., Avanzi, N., Cervi, G., D'Anello, M., Donati, D., Faiardi, D., Ferguson, R.D., Fogliatto, G., Galvani, A., Marsiglio, A., Mirizzi, D.G., Montemartini, M., Orrenius, C., Papeo, G., Piutti, C., Salom, B., Felder, E.R.
Deposit date:2013-07-29
Release date:2013-10-30
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery and Optimization of Pyrrolo[1,2-A]Pyrazinones Leads to Novel and Selective Inhibitors of Pim Kinases.
Bioorg.Med.Chem., 21, 2013
4BZO
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CRYSTAL STRUCTURE OF PIM1 IN COMPLEX WITH A PYRROLO-PYRAZINONE INHIBITOR
Descriptor:SERINE/THREONINE-PROTEIN KINASE PIM-1, N-[(1S)-2-AMINO-1-PHENYLETHYL]-2-[(4S)-7-(2-FLUORO-4-PYRIDINYL)-1-OXO-1,2,3,4-TETRAHYDROPYRROLO[1,2-A]PYRAZIN-4-YL]ACETAMIDE
Authors:Casale, E., Casuscelli, F., Ardini, E., Avanzi, N., Cervi, G., D'Anello, M., Donati, D., Faiardi, D., Ferguson, R.D., Fogliatto, G., Galvani, A., Marsiglio, A., Mirizzi, D.G., Montemartini, M., Orrenius, C., Papeo, G., Piutti, C., Salom, B., Felder, E.R.
Deposit date:2013-07-29
Release date:2013-10-30
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Discovery and Optimization of Pyrrolo[1,2-A]Pyrazinones Leads to Novel and Selective Inhibitors of Pim Kinases.
Bioorg.Med.Chem., 21, 2013
1EWX
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CRYSTAL STRUCTURE OF NATIVE TRYPAREDOXIN I FROM CRITHIDIA FASCICULATA
Descriptor:TRYPAREDOXIN I
Authors:Hofmann, B., Guerrero, S.A., Kalisz, H.M., Menge, U., Nogoceke, E., Montemartini, M., Singh, M., Flohe, L., Hecht, H.J.
Deposit date:2000-04-28
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001
1EZK
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CRYSTAL STRUCTURE OF RECOMBINANT TRYPAREDOXIN I
Descriptor:TRYPAREDOXIN I
Authors:Hofmann, B., Guerrero, S.A., Kalisz, H.M., Menge, U., Nogoceke, E., Montemartini, M., Singh, M., Flohe, L., Hecht, H.J.
Deposit date:2000-05-11
Release date:2000-05-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001
1I5G
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TRYPAREDOXIN II COMPLEXED WITH GLUTATHIONYLSPERMIDINE
Descriptor:TRYPAREDOXIN II, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTATHIONYLSPERMIDINE
Authors:Hofmann, B., Budde, H., Bruns, K., Guerrero, S.A., Kalisz, H.M., Menge, U., Montemartini, M., Nogoceke, E., Steinert, P., Wissing, J.B., Flohe, L., Hecht, H.-J.
Deposit date:2001-02-27
Release date:2001-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structures of tryparedoxins revealing interaction with trypanothione.
Biol.Chem., 382, 2001