1A1U
| SOLUTION STRUCTURE DETERMINATION OF A P53 MUTANT DIMERIZATION DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | P53 | Authors: | Mccoy, M.A, Stavridi, E.S, Waterman, J.L.F, Wieczorek, A, Opella, S.J, Halezonetis, T.D. | Deposit date: | 1997-12-16 | Release date: | 1998-04-08 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain. EMBO J., 16, 1997
|
|
8T7D
| Crystal structure of wild type IDH1 bound to compound 1 | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, N-(4-tert-butylphenyl)-7,8-dimethyl-5,11-dihydro-6H-pyrido[2,3-b][1,5]benzodiazepine-6-carboxamide | Authors: | Lu, J, Abeywickrema, P, Heo, M.R, Parthasarathy, G, McCoy, M, Soisson, S.M. | Deposit date: | 2023-06-20 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (3.444 Å) | Cite: | Mechanistic and Biostructural Studies of Mutant IDH1 To Be Published
|
|
8T7N
| Crystal structure of the R132H mutant of IDH1 bound to compound 1 | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, N-(4-tert-butylphenyl)-7,8-dimethyl-5,11-dihydro-6H-pyrido[2,3-b][1,5]benzodiazepine-6-carboxamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Lu, J, Abeywickrema, P, Heo, M.R, Parthasarathy, G, McCoy, M, Soisson, S.M. | Deposit date: | 2023-06-20 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Mechanistic and Biostructural Studies of Mutant IDH1 To Be Published
|
|
8T7O
| Crystal structure of the R132H mutant of IDH1 bound to AG-120 | Descriptor: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ivosidenib | Authors: | Lu, J, Abeywickrema, P, Heo, M.R, Parthasarathy, G, McCoy, M, Soisson, S.M. | Deposit date: | 2023-06-20 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | Mechanistic and Biostructural Studies of Mutant IDH1 To Be Published
|
|
6BFB
| Crystal structure of a F. nucleatum FMN riboswitch bound to WG-3 | Descriptor: | 5-[(3S,4S)-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl]-6-fluoro-4-methyl-8-oxo-3,4-dihydro-8H-1-thia-4,9b-diazacyclopenta[cd]phenalene-9-carboxylic acid, MAGNESIUM ION, RNA (54-MER), ... | Authors: | Rizvi, N.F, Fischmann, T.O. | Deposit date: | 2017-10-26 | Release date: | 2018-02-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry. ACS Chem. Biol., 13, 2018
|
|
8CG7
| Structure of p53 cancer mutant Y220C with arylation at Cys182 and Cys277 | Descriptor: | 1,2-ETHANEDIOL, 5-iodanyl-2-methylsulfonyl-pyrimidine, Cellular tumor antigen p53, ... | Authors: | Balourdas, D.I, Pichon, M.M, Baud, M.G.J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | Deposit date: | 2023-02-03 | Release date: | 2023-12-13 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Structure-Reactivity Studies of 2-Sulfonylpyrimidines Allow Selective Protein Arylation. Bioconjug.Chem., 34, 2023
|
|