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3MRA
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BU of 3mra by Molmil
M3 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 15 STRUCTURES
Descriptor: Acetylcholine receptor subunit alpha
Authors:Lugovskoy, A.A, Maslennikov, I.V, Utkin, Y.N, Tsetlin, V.I, Cohen, J.B, Arseniev, A.S.
Deposit date:1997-07-15
Release date:1998-01-21
Last modified:2021-01-13
Method:SOLUTION NMR
Cite:Spatial structure of the M3 transmembrane segment of the nicotinic acetylcholine receptor alpha subunit.
Eur.J.Biochem., 255, 1998
6I04
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BU of 6i04 by Molmil
Crystal structure of Sema domain of the Met receptor in complex with FAB
Descriptor: Fab heavy chain, Fab light chain, Hepatocyte growth factor receptor
Authors:Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G.
Deposit date:2018-10-25
Release date:2019-03-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Proc.Natl.Acad.Sci.USA, 116, 2019
1JQ4
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BU of 1jq4 by Molmil
[2Fe-2S] Domain of Methane Monooxygenase Reductase from Methylococcus capsulatus (Bath)
Descriptor: FE2/S2 (INORGANIC) CLUSTER, METHANE MONOOXYGENASE COMPONENT C
Authors:Mueller, J, Lugovskoy, A.A, Wagner, G, Lippard, S.J.
Deposit date:2001-08-03
Release date:2002-01-09
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase.
Biochemistry, 41, 2002
1RF8
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BU of 1rf8 by Molmil
Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ...
Authors:Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G.
Deposit date:2003-11-07
Release date:2003-12-23
Last modified:2024-03-06
Method:SOLUTION NMR
Cite:Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.
Cell(Cambridge,Mass.), 115, 2003
1IBX
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BU of 1ibx by Molmil
NMR STRUCTURE OF DFF40 AND DFF45 N-TERMINAL DOMAIN COMPLEX
Descriptor: CHIMERA OF IGG BINDING PROTEIN G AND DNA FRAGMENTATION FACTOR 45, DNA FRAGMENTATION FACTOR 40
Authors:Zhou, P, Lugovskoy, A.A, McCarty, J.S, Li, P, Wagner, G.
Deposit date:2001-03-29
Release date:2001-05-02
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.
Proc.Natl.Acad.Sci.USA, 98, 2001
6I07
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BU of 6i07 by Molmil
Crystal structure of EpCAM in complex with scFv
Descriptor: Epithelial cell adhesion molecule, GLYCEROL, Single chain Fv
Authors:Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G.
Deposit date:2018-10-25
Release date:2019-03-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HYG
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BU of 6hyg by Molmil
Heteromeric tandem IgG4/IgG1 Fc
Descriptor: IgHG1 and IgHG4 hybrid, ZINC ION
Authors:Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G.
Deposit date:2018-10-21
Release date:2019-03-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM.
Proc.Natl.Acad.Sci.USA, 116, 2019
1D4B
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BU of 1d4b by Molmil
CIDE-N DOMAIN OF HUMAN CIDE-B
Descriptor: HUMAN CELL DEATH-INDUCING EFFECTOR B
Authors:Lugovskoy, A, Zhou, P, Chou, J, McCarty, J, Li, P, Wagner, G.
Deposit date:1999-10-02
Release date:1999-12-17
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis.
Cell(Cambridge,Mass.), 99, 1999
2AZ5
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BU of 2az5 by Molmil
Crystal Structure of TNF-alpha with a small molecule inhibitor
Descriptor: 6,7-DIMETHYL-3-[(METHYL{2-[METHYL({1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-INDOL-3-YL}METHYL)AMINO]ETHYL}AMINO)METHYL]-4H-CHROMEN-4-ONE, Tumor necrosis factor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, ...
Authors:He, M.M.
Deposit date:2005-09-09
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Small-molecule inhibition of TNF-alpha.
Science, 310, 2005

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