Author results

6GUM
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STRUCTURE OF THE A.THALIANA E1 UFD DOMAIN IN COMPLEX WITH E2
Descriptor:SUMO-conjugating enzyme SCE1, SAE2, GLYCEROL
Authors:Liu, B., Lois, L.M., Reverter, D.
Deposit date:2018-06-19
Release date:2019-07-03
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structure of the complex between E1 UFD and E2 in A.thaliana
To Be Published
6GV3
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STRUCTURE OF THE E2 CONJUGATING ENZYME, SCE1, FROM ARABIDOPSIS THALIANA.
Descriptor:SUMO-conjugating enzyme SCE1
Authors:Liu, B., Lois, L.M., Reverter, D.
Deposit date:2018-06-20
Release date:2019-07-03
Method:X-RAY DIFFRACTION (1.201 Å)
Cite:Structure of the E2 conjugating enzyme, SCE1, from Arabidopsis thaliana.
To Be Published
6ILZ
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CRYSTAL STRUCTURE OF PKCIOTA IN COMPLEX WITH INHIBITOR
Descriptor:Protein kinase C iota type, 2-amino-5-[3-(piperazin-1-yl)phenyl]-N-(pyridin-4-yl)pyridine-3-carboxamide
Authors:Baburajendran, N., Hill, J.
Deposit date:2018-10-21
Release date:2019-06-26
Method:X-RAY DIFFRACTION (3.261 Å)
Cite:Fragment-based Discovery of a Small-Molecule Protein Kinase C-iota Inhibitor Binding Post-kinase Domain Residues.
Acs Med.Chem.Lett., 10, 2019
6O1S
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STRUCTURE OF HUMAN PLASMA KALLIKREIN PROTEASE DOMAIN WITH INHIBITOR
Descriptor:Plasma kallikrein, PHOSPHATE ION, 1,2-ETHANEDIOL, ...
Authors:Partridge, J.R., Choy, R.M.
Deposit date:2019-02-21
Release date:2019-03-06
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition.
J.Struct.Biol., 206, 2019
6F8E
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PH DOMAIN FROM TGAPH
Descriptor:Pleckstrin homology domain
Authors:Darvill, N., Liu, B., Matthews, S., Soldati-Favre, D., Rouse, S., Benjamin, S., Blake, T., Dubois, D.J., Hammoudi, P.M., Pino, P.
Deposit date:2017-12-13
Release date:2019-01-30
Method:SOLUTION NMR
Cite:Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites.
Structure, 26, 2018
6DO7
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NMR SOLUTION STRUCTURE OF WILD TYPE HFABP1 WITH GW7647
Descriptor:Fatty acid-binding protein, liver
Authors:Scanlon, M.J., Mohanty, B., Doak, B.C., Patil, R.
Deposit date:2018-06-09
Release date:2019-01-02
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.
J. Biol. Chem., 294, 2019
6DO6
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NMR SOLUTION STRUCTURE OF WILD TYPE APO HFABP1 AT 308 K
Descriptor:Fatty acid-binding protein, liver
Authors:Scanlon, M.J., Mohanty, B., Doak, B.C., Patil, R.
Deposit date:2018-06-09
Release date:2018-12-26
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.
J. Biol. Chem., 294, 2019
6DRG
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NMR SOLUTION STRUCTURE OF WILD TYPE HFABP1 WITH GW7647
Descriptor:Fatty acid-binding protein, liver, 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid
Authors:Scanlon, M.J., Mohanty, B., Doak, B.C., Patil, R.
Deposit date:2018-06-11
Release date:2018-12-26
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor alpha agonists.
J. Biol. Chem., 294, 2019
6E4N
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STRUCTURE OF THE T. BRUCEI TBRGG2 RRM DOMAIN: APO R3 CRYSTAL FORM
Descriptor:RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4O
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STRUCTURE OF APO T. BRUCEI RRM: P4(1)2(1)2 FORM
Descriptor:RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6E4P
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STRUCTURE OF THE T. BRUCEI RRM DOMAIN IN COMPLEX WITH RNA
Descriptor:RNA (5'-R(P*UP*UP*UP*U)-3'), RNA-binding protein, putative
Authors:Schumacher, M.A.
Deposit date:2018-07-18
Release date:2018-12-12
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA.
Nucleic Acids Res., 47, 2019
6F24
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PH DOMAIN FROM PFAPH
Descriptor:C-terminal PH domain from PfAPH
Authors:Darvill, N., Liu, B., Matthews, S., Soldati-Favre, D., Rouse, S., Benjamin, S., Blake, T., Dubois, D.J., Hammoudi, P.M., Pino, P.
Deposit date:2017-11-23
Release date:2018-12-12
Method:SOLUTION NMR
Cite:C-terminal PH domain from P. falciparum acylated plekstrin homology domain containing protein (APH)
To Be Published
6GZ8
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FIRST GERMN DOMAIN OF THE SPORULATION PROTEIN GERM FROM BACILLUS SUBTILIS
Descriptor:Spore germination protein GerM, SODIUM ION, 1,2-ETHANEDIOL
Authors:Trouve, J., Mohamed, A., Leisico, F., Contreras-Martel, C., Liu, B., Mas, C., Rudner, D.Z., Rodrigues, C.D.A., Morlot, C.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural characterization of the sporulation protein GerM from Bacillus subtilis.
J. Struct. Biol., 204, 2018
6GZB
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TANDEM GERMN DOMAINS OF THE SPORULATION PROTEIN GERM FROM BACILLUS SUBTILIS
Descriptor:Spore germination protein GerM, ACETATE ION, 1,2-ETHANEDIOL
Authors:Trouve, J., Mohamed, A., Leisico, F., Contreras-Martel, C., Liu, B., Mas, C., Rudner, D.Z., Rodrigues, C.D.A., Morlot, C.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the sporulation protein GerM from Bacillus subtilis.
J. Struct. Biol., 204, 2018
5YFE
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ENZYMATIC AND STRUCTURAL CHARACTERIZATION OF THE POLY (ETHYLENE TEREPHTHALATE) HYDROLASE PETASE FROM I. SAKAIENSIS
Descriptor:Poly(ethylene terephthalate) hydrolase, SULFATE ION, GLYCEROL
Authors:Bao, R., He, L.H., Liu, B.
Deposit date:2017-09-21
Release date:2018-09-26
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Protein Crystallography and Site-Direct Mutagenesis Analysis of the Poly(ethylene terephthalate) Hydrolase PETase from Ideonella sakaiensis.
Chembiochem, 2018
5YVF
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CRYSTAL STRUCTURE OF BFA1
Descriptor:BFA1
Authors:Pu, H., Zhang, L., Duan, Z.K., Peng, L.W., Liu, L.
Deposit date:2017-11-25
Release date:2018-08-08
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Nucleus-Encoded Protein BFA1 Promotes Efficient Assembly of the Chloroplast ATP Synthase Coupling Factor 1.
Plant Cell, 30, 2018
5O71
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CRYSTAL STRUCTURE OF HUMAN USP25
Descriptor:Ubiquitin carboxyl-terminal hydrolase 25
Authors:Reverter, D., Liu, B.
Deposit date:2017-06-07
Release date:2018-06-20
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.283 Å)
Cite:A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25.
Nat Commun, 9, 2018
6FI7
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E.COLI SIGMA FACTOR S (RPOS) REGION 4
Descriptor:RNA polymerase sigma factor RpoS
Authors:Liu, B., Matthews, S.J.
Deposit date:2018-01-17
Release date:2018-06-06
Last modified:2018-06-13
Method:SOLUTION NMR
Cite:T7 phage factor required for managing RpoS inEscherichia coli.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5NNS
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CRYSTAL STRUCTURE OF HILPMO9B
Descriptor:Glycosyl hydrolase family 61, 2 protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Dimarogona, M., Sandgren, M.
Deposit date:2017-04-10
Release date:2018-05-16
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and molecular dynamics studies of a C1-oxidizing lytic polysaccharide monooxygenase from Heterobasidion irregulare reveal amino acids important for substrate recognition.
FEBS J., 285, 2018
5Z55
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NMR SOLUTION STRUCTURE OF THE KRINGLE DOMAIN OF HUMAN RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTOR 1 (ROR1)
Descriptor:Inactive tyrosine-protein kinase transmembrane receptor ROR1
Authors:Ma, X., Hu, K.F.
Deposit date:2018-01-17
Release date:2018-05-16
Method:SOLUTION NMR
Cite:Backbone and side-chain chemical shift assignments of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1).
Biomol NMR Assign, 12, 2018
5Z1P
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STRUCTURAL BASIS OF THE IMPROVED SWEETNESS AND STABILITY OF THE SINGLE-CHAIN SWEET-TASTING PROTEIN MONELLIN (MNEI)
Descriptor:Monellin chain B,Monellin chain A
Authors:Liu, B.
Deposit date:2017-12-27
Release date:2018-02-21
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure basis of the improved sweetness and thermostability of a unique double-sites single-chain sweet-tasting protein monellin (MNEI) mutant
Biochimie, 154, 2018
5V54
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CRYSTAL STRUCTURE OF 5-HT1B RECEPTOR IN COMPLEX WITH METHIOTHEPIN
Descriptor:5-hydroxytryptamine receptor 1B,OB-1 fused 5-HT1b receptor,5-hydroxytryptamine receptor 1B, 1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine
Authors:Yin, W.C., Zhou, X.E., Yang, D., de Waal, P., Wang, M.T., Dai, A., Cai, X., Huang, C.Y., Liu, P., Yin, Y., Liu, B., Caffrey, M., Melcher, K., Xu, Y., Wang, M.W., Xu, H.E., Jiang, Y.
Deposit date:2017-03-13
Release date:2018-02-07
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:A common antagonistic mechanism for class A GPCRs revealed by the structure of the human 5-HT1B serotonin receptor bound to an antagonist
Cell Discov, 2018
6B6H
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THE CRYO-EM STRUCTURE OF A BACTERIAL CLASS I TRANSCRIPTION ACTIVATION COMPLEX
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Liu, B., Hong, C., Huang, R., Yu, Z., Steitz, T.A.
Deposit date:2017-10-02
Release date:2017-11-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of bacterial transcription activation.
Science, 358, 2017
5H4D
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CRYSTAL STRUCTURE OF HSIRT3 IN COMPLEX WITH A SPECIFIC AGONIST AMIODARONE HYDROCHLORIDE
Descriptor:NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ARG-HIS-LYS, ...
Authors:Zhang, S., Fu, L., Liu, J., Liu, B.
Deposit date:2016-10-31
Release date:2017-11-08
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride
To Be Published
5W5J
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IDENTIFICATION OF POTENT AND SELECTIVE RIPK2 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES
Descriptor:Receptor-interacting serine/threonine-protein kinase 2, N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide, SULFATE ION
Authors:Kreusch, A., Spraggon, G.
Deposit date:2017-06-15
Release date:2017-10-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017