1APL | | CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS | | Descriptor: | DNA (5'-D(*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*CP*AP*TP*TP*TP*AP*C P*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*GP*TP*AP*AP*AP*TP*GP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT-ALPHA2 HOMEODOMAIN) | | Authors: | Wolberger, C., Vershon, A.K., Liu, B., Johnson, A.D., Pabo, C.O. | | Deposit date: | 1993-10-04 | | Release date: | 1993-10-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 67, 1991
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1B9E | | HUMAN INSULIN MUTANT SERB9GLU | | Descriptor: | PROTEIN (INSULIN) | | Authors: | Wang, D.C., Zeng, Z.H., Yao, Z.P., Li, H.M. | | Deposit date: | 1998-11-12 | | Release date: | 1999-11-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Acta Crystallogr.,Sect.D, 55, 1999
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1CN4 | |
1DU0 | | ENGRAILED HOMEODOMAIN Q50A VARIANT DNA COMPLEX | | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*CP*CP*TP*AP*A)-3'), DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*GP*CP*AP*AP*A)-3'), ENGRAILED HOMEODOMAIN | | Authors: | Grant, R.A., Rould, M.A., Klemm, J.D., Pabo, C.O. | | Deposit date: | 2000-01-13 | | Release date: | 2000-07-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Exploring the role of glutamine 50 in the homeodomain-DNA interface: crystal structure of engrailed (Gln50 --> ala) complex at 2.0 A.
Biochemistry, 39, 2000
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1EER | |
1ENH | | STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN | | Descriptor: | ENGRAILED HOMEODOMAIN | | Authors: | Clarke, N.D., Kissinger, C.R., Desjarlais, J., Gilliland, G.L., Pabo, C.O. | | Deposit date: | 1994-05-20 | | Release date: | 1994-08-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural studies of the engrailed homeodomain.
Protein Sci., 3, 1994
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1FSH | |
1HDD | | CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS | | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*GP*CP*CP*AP*TP*GP*TP*AP*AP*TP*TP*AP*C P*CP*TP*AP*A)-3'), DNA (5'-D(*AP*TP*TP*AP*GP*GP*TP*AP*AP*TP*TP*AP*CP*AP*TP*GP*G P*CP*AP*AP*A)-3'), PROTEIN (ENGRAILED HOMEODOMAIN) | | Authors: | Kissinger, C.R., Liu, B., Martin-Blanco, E., Kornberg, T.B., Pabo, C.O. | | Deposit date: | 1991-09-16 | | Release date: | 1992-01-15 | | Last modified: | 2017-02-15 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions.
Cell(Cambridge,Mass.), 63, 1990
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1HPX | | HIV-1 PROTEASE COMPLEXED WITH THE INHIBITOR KNI-272 | | Descriptor: | HIV-1 PROTEASE, (4R)-N-tert-butyl-3-[(2S,3S)-2-hydroxy-3-({N-[(isoquinolin-5-yloxy)acetyl]-S-methyl-L-cysteinyl}amino)-4-phenylbutanoyl]-1,3-thiazolidine-4-carboxamide | | Authors: | Bhat, T.N., Erickson, J.W. | | Deposit date: | 1995-05-18 | | Release date: | 1996-03-08 | | Last modified: | 2012-12-12 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine.
Structure, 3, 1995
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1HVC | | CRYSTAL STRUCTURE OF A TETHERED DIMER OF HIV-1 PROTEASE COMPLEXED WITH AN INHIBITOR | | Descriptor: | HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | | Authors: | Bhat, T.N., Baldwin, E.T., Erickson, J.W. | | Deposit date: | 1994-06-22 | | Release date: | 1994-10-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of a tethered dimer of HIV-1 proteinase complexed with an inhibitor.
Nat.Struct.Biol., 1, 1994
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1HVI | | INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | | Descriptor: | HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | | Authors: | Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W. | | Deposit date: | 1994-01-26 | | Release date: | 1994-04-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
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1HVJ | | INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | | Descriptor: | HIV-1 PROTEASE, N-{1-BENZYL-3-HYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | | Authors: | Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W. | | Deposit date: | 1994-01-26 | | Release date: | 1994-04-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
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1HVK | | INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | | Descriptor: | HIV-1 PROTEASE, N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | | Authors: | Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W. | | Deposit date: | 1994-01-26 | | Release date: | 1994-04-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
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1HVL | | INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE | | Descriptor: | HIV-1 PROTEASE, N-{1-BENZYL-(2R,3R)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | | Authors: | Bhat, T.N., Hosur, M.V., Baldwin, E.T., Erickson, J.W. | | Deposit date: | 1994-01-26 | | Release date: | 1994-04-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-Based Diol Inhibitors of HIV-1 Protease
J.Am.Chem.Soc., 116, 1994
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1HVS | | STRUCTURAL BASIS OF DRUG RESISTANCE FOR THE V82A MUTANT OF HIV-1 PROTEASE: BACKBONE FLEXIBILITY AND SUBSITE REPACKING | | Descriptor: | HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | | Authors: | Baldwin, E.T., Bhat, T.N., Liu, B., Pattabiraman, N., Erickson, J.W. | | Deposit date: | 1994-11-17 | | Release date: | 1995-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase.
Nat.Struct.Biol., 2, 1995
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1MNM | |
1STR | | STREPTAVIDIN DIMERIZED BY DISULFIDE-BONDED PEPTIDE AC-CHPQNT-NH2 DIMER | | Descriptor: | STREPTAVIDIN, AC-CHPQNT-NH2 | | Authors: | Katz, B.A., Cass, R.T., Liu, B., Arze, R., Collins, N. | | Deposit date: | 1995-09-12 | | Release date: | 1996-03-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Topochemical catalysis achieved by structure-based ligand design.
J.Biol.Chem., 270, 1995
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1STS | | STREPTAVIDIN DIMERIZED BY DISULFIDE-BONDED PEPTIDE FCHPQNT-NH2 DIMER | | Descriptor: | STREPTAVIDIN, FCHPQNT-NH2 | | Authors: | Katz, B.A., Cass, R.T., Liu, B., Arze, R., Collins, N. | | Deposit date: | 1995-09-12 | | Release date: | 1996-03-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Topochemical catalysis achieved by structure-based ligand design.
J.Biol.Chem., 270, 1995
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1T0Z | | STRUCTURE OF AN EXCITATORY INSECT-SPECIFIC TOXIN WITH AN ANALGESIC EFFECT ON MAMMALIAN FROM SCORPION BUTHUS MARTENSII KARSCH | | Descriptor: | insect neurotoxin, SULFATE ION | | Authors: | Li, C., Guan, R.-J., Xiang, Y., Zhang, Y., Wang, D.-C. | | Deposit date: | 2004-04-14 | | Release date: | 2004-12-28 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of an excitatory insect-specific toxin with an analgesic effect on mammals from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 61, 2005
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1UDE | | CRYSTAL STRUCTURE OF THE INORGANIC PYROPHOSPHATASE FROM THE HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS HORIKOSHII OT3 | | Descriptor: | Inorganic pyrophosphatase | | Authors: | Liu, B., Gao, R., Zhou, W., Bartlam, M., Rao, Z. | | Deposit date: | 2003-04-29 | | Release date: | 2004-01-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | Crystal Structure of the Hyperthermophilic Inorganic Pyrophosphatase from the Archaeon Pyrococcus horikoshii.
Biophys.J., 86, 2004
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1VWA | | STREPTAVIDIN-FSHPQNT | | Descriptor: | STREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ | | Authors: | Katz, B.A., Cass, R.T. | | Deposit date: | 1997-03-03 | | Release date: | 1998-03-18 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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1VWB | | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 11.8 | | Descriptor: | STREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ | | Authors: | Katz, B.A., Cass, R.T. | | Deposit date: | 1997-03-03 | | Release date: | 1998-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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1VWC | | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 2.0 | | Descriptor: | STREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ | | Authors: | Katz, B.A., Cass, R.T. | | Deposit date: | 1997-03-03 | | Release date: | 1998-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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1VWD | | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 3.0 | | Descriptor: | STREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ | | Authors: | Katz, B.A., Cass, R.T. | | Deposit date: | 1997-03-03 | | Release date: | 1998-03-18 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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1VWE | | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 3.6 | | Descriptor: | STREPTAVIDIN, PEPTIDE LIGAND CONTAINING HPQ | | Authors: | Katz, B.A., Cass, R.T. | | Deposit date: | 1997-03-03 | | Release date: | 1998-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
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