1B8G | | 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE | | Descriptor: | PROTEIN (1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE), PYRIDOXAL-5'-PHOSPHATE | | Authors: | Capitani, G., Hohenester, E., Feng, L., Storici, P., Kirsch, J.F., Jansonius, J.N. | | Deposit date: | 1999-01-31 | | Release date: | 2000-01-26 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene.
J.Mol.Biol., 294, 1999
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1M4N | | CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH [2-(AMINO-OXY)ETHYL](5'-DEOXYADENOSIN-5'-YL)(METHYL)SULFONIUM | | Descriptor: | 1-aminocyclopropane-1-carboxylate synthase, PYRIDOXAL-5'-PHOSPHATE, (2-AMINOOXY-ETHYL)-[5-(6-AMINO-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHYL]-METHYL-SULFONIUM, ... | | Authors: | Capitani, G., Eliot, A.C., Gut, H., Khomutov, R.M., Kirsch, J.F., Grutter, M.G. | | Deposit date: | 2002-07-03 | | Release date: | 2003-04-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding.
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647, 2003
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1M7Y | | CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-AMINOETHOXYVINYLGLYCINE | | Descriptor: | 1-aminocyclopropane-1-carboxylate synthase, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, (4R)-2-METHYLPENTANE-2,4-DIOL | | Authors: | Capitani, G., McCarthy, D., Gut, H., Gruetter, M.G., Kirsch, J.F. | | Deposit date: | 2002-07-23 | | Release date: | 2002-12-23 | | Last modified: | 2011-12-28 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor
L-Aminoethoxyvinylglycine
J.Biol.Chem., 277, 2002
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1MGV | | CRYSTAL STRUCTURE OF THE R391A MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | | Descriptor: | 7,8-diamino-pelargonic acid aminotransferase, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Eliot, A.C., Sandmark, J., Schneider, G., Kirsch, J.F. | | Deposit date: | 2002-08-16 | | Release date: | 2002-11-27 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Dual-Specific Active Site of 7,8-Diaminopelargonic Acid Synthase and the Effect of the R391A Mutation
Biochemistry, 41, 2002
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1S06 | | CRYSTAL STRUCTURE OF THE R253K MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | | Descriptor: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | Authors: | Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F. | | Deposit date: | 2003-12-30 | | Release date: | 2004-03-23 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1S07 | | CRYSTAL STRUCTURE OF THE R253A MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | | Descriptor: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F. | | Deposit date: | 2003-12-30 | | Release date: | 2004-03-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1S08 | | CRYSTAL STRUCTURE OF THE D147N MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | | Descriptor: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | Authors: | Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F. | | Deposit date: | 2003-12-30 | | Release date: | 2004-03-23 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1S09 | | CRYSTAL STRUCTURE OF THE Y144F MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | | Descriptor: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | Authors: | Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F. | | Deposit date: | 2003-12-30 | | Release date: | 2004-03-23 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1S0A | | CRYSTAL STRUCTURE OF THE Y17F MUTANT OF 7,8-DIAMINOPELARGONIC ACID SYNTHASE | | Descriptor: | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, SODIUM ION | | Authors: | Sandmark, J., Eliot, A.C., Famm, K., Schneider, G., Kirsch, J.F. | | Deposit date: | 2003-12-30 | | Release date: | 2004-03-23 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
Biochemistry, 43, 2004
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1TOE | | UNLIGANDED STRUCTURE OF HEXAMUTANT + A293D MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE | | Descriptor: | Aspartate aminotransferase, SULFATE ION | | Authors: | Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F. | | Deposit date: | 2004-06-14 | | Release date: | 2004-10-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
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1TOG | | HYDROCINNAMIC ACID-BOUND STRUCTURE OF SRHEPT + A293D MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE | | Descriptor: | Aspartate aminotransferase, HYDROCINNAMIC ACID | | Authors: | Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F. | | Deposit date: | 2004-06-14 | | Release date: | 2004-10-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
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1TOI | | HYDROCINNAMIC ACID-BOUND STRUCTURE OF HEXAMUTANT + A293D MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE | | Descriptor: | Aspartate aminotransferase, HYDROCINNAMIC ACID | | Authors: | Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F. | | Deposit date: | 2004-06-14 | | Release date: | 2004-10-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
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1TOJ | | HYDROCINNAMIC ACID-BOUND STRUCTURE OF SRHEPT MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE | | Descriptor: | Aspartate aminotransferase, HYDROCINNAMIC ACID | | Authors: | Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F. | | Deposit date: | 2004-06-14 | | Release date: | 2004-10-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
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1TOK | | MALEIC ACID-BOUND STRUCTURE OF SRHEPT MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE | | Descriptor: | Aspartate aminotransferase, MALEIC ACID | | Authors: | Chow, M.A., McElroy, K.E., Corbett, K.D., Berger, J.M., Kirsch, J.F. | | Deposit date: | 2004-06-14 | | Release date: | 2004-10-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
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1YNU | | CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH L-VINYLGLYCINE | | Descriptor: | 1-aminocyclopropane-1-carboxylate synthase, NICKEL (II) ION, POTASSIUM ION, ... | | Authors: | Capitani, G., Tschopp, M., Eliot, A.C., Kirsch, J.F., Grutter, M.G. | | Deposit date: | 2005-01-25 | | Release date: | 2005-05-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine.
Febs Lett., 579, 2005
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2G2U | | CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | Authors: | Reynolds, K.A., Thomson, J.M., Corbett, K.D., Bethel, C.R., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M. | | Deposit date: | 2006-02-16 | | Release date: | 2006-07-04 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
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2G2W | | CRYSTAL STRUCTURE OF THE SHV D104K BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | Authors: | Reynolds, K.A., Thomson, J.M., Corbett, K.D., Bethel, C.R., Berger, J.M., Kirsch, J.F., Bonomo, R.A., Handel, T.M. | | Deposit date: | 2006-02-16 | | Release date: | 2006-07-04 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface.
J.Biol.Chem., 281, 2006
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3C4O | | CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) E73M/S130K/S146M COMPLEX | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION | | Authors: | Reynolds, K.A., Hanes, M.S., Thomson, J.M., Antczak, A.J., Berger, J.M., Bonomo, R.A., Kirsch, J.F., Handel, T.M. | | Deposit date: | 2008-01-30 | | Release date: | 2008-05-27 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
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3C4P | | CRYSTAL STRUCTURE OF THE SHV-1 BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) E73M COMPLEX | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION | | Authors: | Reynolds, K.A., Hanes, M.S., Thomson, J.M., Antczak, A.J., Berger, J.M., Bonomo, R.A., Kirsch, J.F., Handel, T.M. | | Deposit date: | 2008-01-30 | | Release date: | 2008-05-27 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
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3FSL | | CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE TRIPPLE MUTANT (P181Q,R183G,A321K) FROM ESCHERICHIA COLI AT 2.35 A RESOLUTION | | Descriptor: | Aromatic-amino-acid aminotransferase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | | Authors: | Malashkevich, V.N., Ng, B., Kirsch, J.F. | | Deposit date: | 2009-01-09 | | Release date: | 2009-01-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of tyrosine aminotransferase tripple mutant (P181Q,R183G,A321K) from Escherichia coli at 2.35 A resolution
To be Published
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3N4I | | CRYSTAL STRUCTURE OF THE SHV-1 D104E BETA-LACTAMASE/BETA-LACTAMASE INHIBITOR PROTEIN (BLIP) COMPLEX | | Descriptor: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | | Authors: | Hanes, M.S., Reynolds, K.A., McNamara, C., Ghosh, P., Bonomo, R.A., Kirsch, J.F., Handel, T.M. | | Deposit date: | 2010-05-21 | | Release date: | 2011-03-09 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Specificity and Cooperativity at beta-lactamase Position 104 in TEM-1/BLIP and SHV-1/BLIP interactions
Proteins, 79, 2011
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1AHE | | ASPARTATE AMINOTRANSFERASE HEXAMUTANT | | Descriptor: | ASPARTATE AMINOTRANSFERASE, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Malashkevich, V.N., Jansonius, J.N. | | Deposit date: | 1995-02-22 | | Release date: | 1995-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase.
Nat.Struct.Biol., 2, 1995
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1AHF | | ASPARTATE AMINOTRANSFERASE HEXAMUTANT | | Descriptor: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, INDOLYLPROPIONIC ACID, ... | | Authors: | Malashkevich, V.N., Jansonius, J.N. | | Deposit date: | 1995-02-22 | | Release date: | 1995-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase.
Nat.Struct.Biol., 2, 1995
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1AHG | | ASPARTATE AMINOTRANSFERASE HEXAMUTANT | | Descriptor: | Aspartate aminotransferase, TYROSINE, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Malashkevich, V.N., Jansonius, J.N. | | Deposit date: | 1995-02-22 | | Release date: | 1995-09-15 | | Last modified: | 2018-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase.
Nat.Struct.Biol., 2, 1995
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1AHX | | ASPARTATE AMINOTRANSFERASE HEXAMUTANT | | Descriptor: | ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, HYDROCINNAMIC ACID | | Authors: | Malashkevich, V.N., Jansonius, J.N. | | Deposit date: | 1995-02-21 | | Release date: | 1995-09-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Alternating arginine-modulated substrate specificity in an engineered tyrosine aminotransferase.
Nat.Struct.Biol., 2, 1995
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