Author results

5FBO
  • Download 5fbo
  • View 5fbo
Molmil generated image of 5fbo
BTK-INHIBITOR CO-STRUCTURE
Descriptor:Tyrosine-protein kinase BTK, 4-[8-azanyl-3-[(3~{R},6~{S})-1-cyclopropylcarbonyl-6-methyl-piperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-3-fluoranyl-~{N}-[4-(trifluoromethyl)pyridin-2-yl]benzamide, 4-[8-azanyl-3-[(2~{S})-1-[4-(dimethylamino)butanoyl]pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-(1,3-thiazol-2-yl)benzamide
Authors:Fischmann, T.O.
Deposit date:2015-12-14
Release date:2016-03-23
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.894 Å)
Cite:Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis.
ACS Med Chem Lett, 7, 2016
5FBN
  • Download 5fbn
  • View 5fbn
Molmil generated image of 5fbn
BTK KINASE DOMAIN WITH INHIBITOR 1
Descriptor:Tyrosine-protein kinase BTK, 4-[8-azanyl-3-[(3~{R})-1-(3-methyloxetan-3-yl)carbonylpiperidin-3-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-[4-(trifluoromethyl)pyridin-2-yl]benzamide, 4-[8-azanyl-3-[(2~{S})-1-[4-(dimethylamino)butanoyl]pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-~{N}-(1,3-thiazol-2-yl)benzamide, ...
Authors:Raaijmakers, H.C.A., Vu-Pham, D.
Deposit date:2015-12-14
Release date:2016-02-03
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of 8-Amino-imidazo[1,5-a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis.
Acs Med.Chem.Lett., 7, 2016
4HFW
  • Download 4hfw
  • View 4hfw
Molmil generated image of 4hfw
ANTI ROTAVIRUS ANTIBODY
Descriptor:6-26 Fab Light chain, 6-26 Fab Heavy chain, SULFATE ION
Authors:Spiller, B.W., Aiyegbo, M., Crowe, J.E.
Deposit date:2012-10-05
Release date:2013-05-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
3ZG6
  • Download 3zg6
  • View 3zg6
Molmil generated image of 3zg6
THE NOVEL DE-LONG CHAIN FATTY ACID FUNCTION OF HUMAN SIRT6
Descriptor:NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-6, PEPTIDE, ZINC ION, ...
Authors:Wang, Y., Hao, Q.
Deposit date:2012-12-15
Release date:2013-04-03
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine
Nature, 496, 2013
2QUS
  • Download 2qus
  • View 2qus
Molmil generated image of 2qus
HAMMERHEAD RIBOZYME G12A MUTANT PRE-CLEAVAGE
Descriptor:Hammerhead ribozyme, MAGNESIUM ION
Authors:Chi, Y.I., Scott, W.G., Kim, S.H.
Deposit date:2007-08-06
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
2QUW
  • Download 2quw
  • View 2quw
Molmil generated image of 2quw
HAMMERHEAD RIBOZYME G12A MUTANT AFTER CLEAVAGE
Descriptor:Hammerhead ribozyme, cleaved fragment, MAGNESIUM ION
Authors:Chi, Y.I., Scott, W.G., Kim, S.H.
Deposit date:2007-08-06
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Capturing hammerhead ribozyme structures in action by modulating general base catalysis.
Plos Biol., 6, 2008
2JMP
  • Download 2jmp
  • View 2jmp
Molmil generated image of 2jmp
STRUCTURE FOR THE N-TERMINUS OF CHROMOSOMAL REPLICATION INITIATION PROTEIN DNAA FROM M. GENITALIUM
Descriptor:Chromosomal replication initiator protein dnaA
Authors:Lowery, T.J., Pelton, J.G., Wemmer, D.E., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-11-27
Release date:2007-07-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of the N-terminal domain of the replication initiator protein DnaA.
J.Struct.Funct.Genom., 8, 2007
2HYB
  • Download 2hyb
  • View 2hyb
Molmil generated image of 2hyb
CRYSTAL STRUCTURE OF HEXAMERIC DSREFH
Descriptor:Putative sulfurtransferase dsrE, Intracellular sulfur oxidation protein dsrF, DsrH
Authors:Shin, D.H., Connie, H., Schulte, A., Dahl, C., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-08-04
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of hexameric DsrEFH
To be Published
2HQB
  • Download 2hqb
  • View 2hqb
Molmil generated image of 2hqb
CRYSTAL STRUCTURE OF A TRANSCRIPTIONAL ACTIVATOR OF COMK GENE FROM BACILLUS HALODURANS
Descriptor:Transcriptional activator of comK gene
Authors:Xu, Q.S., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-07-18
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a transcriptional activator of comK gene from Bacillus halodurans.
Proteins, 69, 2007
2HQL
  • Download 2hql
  • View 2hql
Molmil generated image of 2hql
CRYSTAL STRUCTURE OF A SMALL SINGLE-STRANDED DNA BINDING PROTEIN FROM MYCOPLASMA PNEUMONIAE
Descriptor:Hypothetical protein MG376 homolog
Authors:Das, D., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-07-18
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a novel single-stranded DNA binding protein from Mycoplasma pneumoniae.
Proteins, 67, 2007
2I6W
  • Download 2i6w
  • View 2i6w
Molmil generated image of 2i6w
CRYSTAL STRUCTURE OF THE MULTIDRUG EFFLUX TRANSPORTER ACRB
Descriptor:Acriflavine resistance protein B
Authors:Das, D., Xu, Q.S., Kim, S.H.
Deposit date:2006-08-29
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids.
J.Struct.Biol., 158, 2007
2I1L
  • Download 2i1l
  • View 2i1l
Molmil generated image of 2i1l
CRYSTAL STRUCTURE OF THE C2 FORM OF FAD SYNTHETASE FROM THERMOTOGA MARITIMA
Descriptor:Riboflavin kinase/FMN adenylyltransferase
Authors:Wang, W., Shin, D.H., Yokota, H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-08-14
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the C2 form of FAD synthetase from Thermotoga maritima
To be Published
2I14
  • Download 2i14
  • View 2i14
Molmil generated image of 2i14
CRYSTAL STRUCTURE OF NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE FROM PYROCOCCUS FURIOSUS
Descriptor:Nicotinate-nucleotide pyrophosphorylase, ZINC ION, 1-ALPHA-PYROPHOSPHORYL-2-ALPHA,3-ALPHA-DIHYDROXY-4-BETA-CYCLOPENTANE-METHANOL-5-PHOSPHATE
Authors:Shin, D.H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-08-12
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of nicotinate-nucleotide pyrophosphorylase from Pyrococcus furiosus
To be Published
2I15
  • Download 2i15
  • View 2i15
Molmil generated image of 2i15
CRYSTAL STRUCTURE OF MPN423 FROM MYCOPLASMA PNEUMONIAE
Descriptor:Hypothetical protein MG296 homolog
Authors:Shin, D.H., Yokota, H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-08-12
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of MPN423 from Mycoplasma pneumoniae
To be Published
2HY5
  • Download 2hy5
  • View 2hy5
Molmil generated image of 2hy5
CRYSTAL STRUCTURE OF DSREFH
Descriptor:Putative sulfurtransferase dsrE, Intracellular sulfur oxidation protein dsrF, DsrH
Authors:Shin, D.H., Schulte, A., Dahl, C., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-08-04
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of DsrEFH
To be Published
2I1O
  • Download 2i1o
  • View 2i1o
Molmil generated image of 2i1o
CRYSTAL STRUCTURE OF A NICOTINATE PHOSPHORIBOSYLTRANSFERASE FROM THERMOPLASMA ACIDOPHILUM
Descriptor:Nicotinate Phosphoribosyltransferase, PHOSPHATE ION, ZINC ION, ...
Authors:Shin, D.H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-08-14
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of a zinc ion bound Nicotinate Phosphoribosyltransferase from Thermoplasma acidophilum
To be Published
2HEK
  • Download 2hek
  • View 2hek
Molmil generated image of 2hek
CRYSTAL STRUCTURE OF O67745, A HYPOTHETICAL PROTEIN FROM AQUIFEX AEOLICUS AT 2.0 A RESOLUTION.
Descriptor:Hypothetical protein, PHOSPHATE ION, ZINC ION, ...
Authors:Oganesyan, V., Jancarik, J., Adams, P.D., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus.
Acta Crystallogr.,Sect.F, 63, 2007
2FVO
  • Download 2fvo
  • View 2fvo
Molmil generated image of 2fvo
DOCKING OF THE MODIFIED RF1 X-RAY STRUCTURE INTO THE LOW RESOLUTION CRYO-EM MAP OF E.COLI 70S RIBOSOME BOUND WITH RF1
Descriptor:Peptide chain release factor 1
Authors:Rawat, U., Gao, H., Zavialov, A., Gursky, R., Ehrenberg, M., Frank, J.
Deposit date:2006-01-31
Release date:2006-04-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (12.8 Å)
Cite:Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM.
J.Mol.Biol., 357, 2006
2BA2
  • Download 2ba2
  • View 2ba2
Molmil generated image of 2ba2
CRYSTAL STRUCTURE OF THE DUF16 DOMAIN OF MPN010 FROM MYCOPLASMA PNEUMONIAE
Descriptor:Hypothetical UPF0134 protein MPN010
Authors:Shin, D.H., Kim, J.-S., Yokota, H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-10-13
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the DUF16 domain of MPN010 from Mycoplasma pneumoniae.
Protein Sci., 15, 2006
2AHD
  • Download 2ahd
  • View 2ahd
Molmil generated image of 2ahd
THE APO STRUCTURE OF METHANOCOCCUS JANNASCHII PHOSPHODIESTERASE MJ0936
Descriptor:Phosphodiesterase MJ0936
Authors:Chen, S., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-07-27
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Apo structure of Methanococcus jannaschii phosphodiesterase MJ0936
TO BE PUBLISHED
1ZXJ
  • Download 1zxj
  • View 1zxj
Molmil generated image of 1zxj
CRYSTAL STRUCTURE OF THE HYPTHETICAL MYCOPLASMA PROTEIN, MPN555
Descriptor:Hypothetical protein MG377 homolog
Authors:Schulze-Gahmen, U., Aono, S., Shengfeng, C., Yokota, H., Kim, R., Kim, S.-H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-06-08
Release date:2005-07-26
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function.
Acta Crystallogr.,Sect.D, 61, 2005
1Z0Z
  • Download 1z0z
  • View 1z0z
Molmil generated image of 1z0z
CRYSTAL STRUCTURE OF A NAD KINASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH NAD
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Liu, J., Lou, Y., Yokota, H., Adams, P.D., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-03-02
Release date:2005-04-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structures of an NAD Kinase from Archaeoglobus fulgidus in Complex with ATP, NAD, or NADP
J.Mol.Biol., 354, 2005
1Z0S
  • Download 1z0s
  • View 1z0s
Molmil generated image of 1z0s
CRYSTAL STRUCTURE OF AN NAD KINASE FROM ARCHAEOGLOBUS FULGIDUS IN COMPLEX WITH ATP
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Liu, J., Lou, Y., Yokota, H., Adams, P.D., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-03-02
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of an NAD Kinase from Archaeoglobus fulgidus in Complex with ATP, NAD, or NADP
J.Mol.Biol., 354, 2005
1Z0U
  • Download 1z0u
  • View 1z0u
Molmil generated image of 1z0u
CRYSTAL STRUCTURE OF A NAD KINASE FROM ARCHAEOGLOBUS FULGIDUS BOUND BY NADP
Descriptor:Probable inorganic polyphosphate/ATP-NAD kinase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Liu, J., Lou, Y., Yokota, H., Adams, P.D., Kim, R., Kim, S.H., Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-03-02
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of an NAD Kinase from Archaeoglobus fulgidus in Complex with ATP, NAD, or NADP
J.Mol.Biol., 354, 2005
1YT5
  • Download 1yt5
  • View 1yt5
Molmil generated image of 1yt5
CRYSTAL STRUCTURE OF NAD KINASE FROM THERMOTOGA MARITIMA
Descriptor:inorganic polyphosphate/ATP-NAD kinase, SULFATE ION
Authors:Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-09
Release date:2005-04-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution.
Acta Crystallogr.,Sect.F, 61, 2005