1EJ5
| SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP | Descriptor: | WISKOTT-ALDRICH SYNDROME PROTEIN | Authors: | Kim, A.S, Kakalis, L.T, Abdul-Manan, N, Liu, G.A, Rosen, M.K. | Deposit date: | 2000-02-29 | Release date: | 2000-04-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature, 404, 2000
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6ORT
| Crystal Structure of Bos taurus Mxra8 Ectodomain | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Matrix remodeling-associated protein 8 | Authors: | Fremont, D.H, Kim, A.S, Nelson, C.A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-04-30 | Release date: | 2020-03-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host Microbe, 27, 2020
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6MWX
| CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-69 Antibody | Descriptor: | E1, E2, EEEV-69 antibody heavy chain, ... | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-30 | Release date: | 2018-12-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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6MW9
| CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody | Descriptor: | E1, E2, EEEV-3 antibody heavy chain, ... | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-29 | Release date: | 2018-12-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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7CW3
| Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CW0
| Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CW2
| Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex) | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CVZ
| Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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7CVY
| Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124 | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | Deposit date: | 2020-08-27 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies. Proc.Natl.Acad.Sci.USA, 117, 2020
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1T84
| Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor | Descriptor: | (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL, Wiskott-Aldrich syndrome protein | Authors: | Peterson, J.R, Bickford, L.C, Morgan, D, Kim, A.S, Ouerfelli, O, Kirschner, M.W, Rosen, M.K. | Deposit date: | 2004-05-11 | Release date: | 2004-07-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation. Nat.Struct.Mol.Biol., 11, 2004
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6MUI
| CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-42 antibody | Descriptor: | E1, E2, EEEV-42 antibody heavy chain, ... | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-23 | Release date: | 2018-12-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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6MX7
| CryoEM structure of chimeric Eastern Equine Encephalitis Virus: Genome-Binding Capsid N-terminal Domain | Descriptor: | Capsid | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-30 | Release date: | 2018-12-19 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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6MWV
| CryoEM structure of Chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-58 Antibody | Descriptor: | E1, E2, EEEV-58 antibody heavy chain, ... | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-30 | Release date: | 2018-12-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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6MX4
| CryoEM structure of chimeric Eastern Equine Encephalitis Virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid, ... | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-30 | Release date: | 2018-12-19 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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6NK3
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6NK7
| Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ... | Authors: | Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-01-04 | Release date: | 2019-05-22 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.99 Å) | Cite: | Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell, 177, 2019
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6NK6
| Electron Cryo-Microscopy Of Chikungunya VLP in complex with mouse Mxra8 receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 glycoprotein, ... | Authors: | Basore, K, Kim, A.S, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-01-04 | Release date: | 2019-05-22 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor. Cell, 177, 2019
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6MWC
| CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-5 antibody | Descriptor: | E1, E2, EEEV-5 antibody heavy chain, ... | Authors: | Hasan, S.S, Sun, C, Kim, A.S, Watanabe, Y, Chen, C.L, Klose, T, Buda, G, Crispin, M, Diamond, M.S, Klimstra, W.B, Rossmann, M.G. | Deposit date: | 2018-10-29 | Release date: | 2018-12-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization. Cell Rep, 25, 2018
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6W2U
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7SFW
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7SFU
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7SFV
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8SQN
| CryoEM structure of Western equine encephalitis virus VLP in complex with the chimeric Du-D1-Mo-D2 MXRA8 receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DuD1MoD2 chimeric MXRA8, E1 envelope glycoprotein, ... | Authors: | Zimmerman, M.I, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2023-05-04 | Release date: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8. Cell, 186, 2023
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6CRJ
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8DAQ
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