Author results

1E6U
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE
分子名称:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
著者Rosano, C., Izzo, G., Bolognesi, M.
登録日2000-08-23
公開日2000-10-22
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
1E7Q
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE S107A
分子名称:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
著者Rosano, C., Izzo, G., Bolognesi, M.
登録日2000-09-07
公開日2000-10-18
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
1E7R
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE Y136E
分子名称:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
著者Rosano, C., Izzo, G., Bolognesi, M.
登録日2000-09-07
公開日2000-10-18
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
1E7S
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GDP 4-KETO-6-DEOXY-D-MANNOSE EPIMERASE REDUCTASE K140R
分子名称:GDP-FUCOSE SYNTHETASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETYLPHOSPHATE, ...
著者Rosano, C., Zuccotti, S., Izzo, G., Bolognesi, M.
登録日2000-09-07
公開日2000-10-18
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants
J.Mol.Biol., 303, 2000
2BMC
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AURORA-2 T287D T288D COMPLEXED WITH PHA-680632
分子名称:SERINE THREONINE-PROTEIN KINASE 6, (3E)-N-(2,6-DIETHYLPHENYL)-3-{[4-(4-METHYLPIPERAZIN-1-YL)BENZOYL]IMINO}PYRROLO[3,4-C]PYRAZOLE-5(3H)-CARBOXAMIDE
著者Cameron, A.D., Izzo, G., Sagliano, A., Rusconi, L., Storici, P., Fancelli, D., Berta, D., Bindi, S., Catana, C., Forte, B., Giordano, P., Mantegani, S., Meroni, M., Moll, J., Pittala, V., Severino, D., Tonani, R., Varasi, M., Vulpetti, A., Vianello, P.
登録日2005-03-11
公開日2005-03-17
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition.
J.Med.Chem., 48, 2005
2J4Z
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STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-680626
分子名称:SERINE THREONINE-PROTEIN KINASE 6, 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC
著者Cameron, A.D., Izzo, G., Storici, P., Rusconi, L., Fancelli, D., Varasi, M., Berta, D., Bindi, S., Forte, B., Severino, D., Tonani, R., Vianello, P.
登録日2006-09-08
公開日2006-11-06
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
J. Med. Chem., 49, 2006
2J50
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STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-739358
分子名称:SERINE/THREONINE-PROTEIN KINASE 6, N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, SULFATE ION
著者Cameron, A.D., Izzo, G., Storici, P., Rusconi, L., Fancelli, D., Varasi, M., Berta, D., Bindi, S., Forte, B., Severino, D., Tonani, R., Vianello, P.
登録日2006-09-08
公開日2006-11-06
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile.
J.Med.Chem., 49, 2006
1P82
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NMR STRUCTURE OF 1-25 FRAGMENT OF MYCOBACTERIUM TUBERCULOSIS CPN10
分子名称:10 kDa chaperonin
著者Ciutti, A., Spiga, O., Giannozzi, E., Scarselli, M., Di Maro, D., Calamandrei, D., Niccolai, N., Bernini, A.
登録日2003-05-06
公開日2003-05-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of 1-25 fragment of Cpn10 from Mycobacterium Tuberculosis
To be Published
1P83
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NMR STRUCTURE OF 1-25 FRAGMENT OF MYCOBACTERIUM TUBERCULOSIS CPN10
分子名称:10 kDa chaperonin
著者Ciutti, A., Spiga, O., Giannozzi, E., Scarselli, M., Di Maro, D., Calamandrei, D., Niccolai, N., Bernini, A.
登録日2003-05-06
公開日2003-05-27
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of 1-25 fragment of Cpn10 from Mycobacterium Tuberculosis
To be Published