Author results

3CG7
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CRYSTAL STRUCTURE OF CELL-DEATH RELATED NUCLEASE 4 (CRN-4)
Descriptor:Cell death-related nuclease 4, ZINC ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2008-03-05
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3CM5
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CRYSTAL STRUCTURE OF CELL-DEATH RELATED NUCLEASE 4 (CRN-4) BOUND WITH MN
Descriptor:Cell death-related nuclease 4, ZINC ION, MANGANESE (II) ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3CM6
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CRYSTAL STRUCTURE OF CELL-DEATH RELATED NUCLEASE 4 (CRN-4) BOUND WITH ER
Descriptor:Cell death-related nuclease 4, ZINC ION, ERBIUM (III) ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3NGY
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CRYSTAL STRUCTURE OF RNASE T (E92G MUTANT)
Descriptor:Ribonuclease T, his tag sequence, COBALT (II) ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGZ
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A NON-PREFERRED SSDNA (GC) WITH ONE MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, 5'-D(P*GP*C)-3', MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH0
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A NON-PREFERRED SSDNA (AAC)
Descriptor:Ribonuclease T, 5'-D(*TP*TP*AP*CP*AP*AP*C)-3'
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH1
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A PREFERRED SSDNA (TAGG) WITH TWO MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, 5'-D(*TP*TP*AP*TP*AP*GP*G)-3', MAGNESIUM ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.107 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH2
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A STEM DNA WITH A 3' OVERHANG
Descriptor:Ribonuclease T, 5'-D(P*TP*TP*AP*CP*AP*AP*C)-3'
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3V9S
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A PRODUCT SSDNA (AAC) WITH ONE MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, DNA (5'-D(*TP*TP*AP*CP*AP*AP*C)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9U
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A PREFERRED SSDNA (AAT) WITH TWO MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, DNA (5'-D(*TP*TP*AP*CP*AP*AP*T)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9W
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A PREFERRED SSDNA (TTA) WITH TWO MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, DNA (5'-D(*GP*CP*TP*TP*A)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9X
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A PREFERRED SSDNA (AAA) WITH TWO MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, DNA (5'-D(*TP*TP*AP*TP*AP*AP*A)-3'), MAGNESIUM ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9Z
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A PRODUCT SSDNA (ACC) WITH ONE MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, DNA (5'-D(*TP*TP*AP*CP*AP*CP*C)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3VA0
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A DI-NUCLEOTIDE PRODUCT (GG) WITH ONE MG IN THE ACTIVE SITE
Descriptor:Ribonuclease T, DNA (5'-D(*GP*G)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3VA3
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A DUPLEX DNA PRODUCT (STEM LOOP DNA WITH 2 NUCLEOTIDE 3' OVERHANG)
Descriptor:Ribonuclease T, DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3'), COBALT (II) ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.714 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
5DK5
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CRYSTAL STRUCTURE OF CRN-4-MES COMPLEX
Descriptor:Cell death-related nuclease 4, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2015-09-03
Release date:2016-08-24
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016
1M07
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RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA)
Descriptor:5'-D(*AP*CP*GP*A)-3', Ribonuclease
Authors:Leu, Y.-J., Chern, S.-S., Wang, S.-C., Hsiao, Y.-Y., Amiraslanov, I., Liaw, Y.-C., Liao, Y.-D.
Deposit date:2002-06-12
Release date:2003-01-21
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography
J.Biol.Chem., 278, 2003
3HKM
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CRYSTAL STRUCTURE OF RICE(ORYZA SATIVA) RRP46
Descriptor:Os03g0854200 protein
Authors:Yang, C.-C., Wang, Y.-T., Hsiao, Y.-Y., Doudeva, L.G., Yuan, H.S.
Deposit date:2009-05-25
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9845 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
3KRN
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CRYSTAL STRUCTURE OF C. ELEGANS CELL-DEATH-RELATED NUCLEASE 5(CRN-5)
Descriptor:Protein C14A4.5, confirmed by transcript evidence
Authors:Yang, C.-C., Wang, Y.-T., Hsiao, Y.-Y., Doudeva, L.G., Chow, S.Y., Yuan, H.S.
Deposit date:2009-11-19
Release date:2010-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.918 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
4KAZ
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A Y STRUCTURED DNA
Descriptor:Ribonuclease T, DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KB0
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A BLUGE DNA (TWO NUCLEOTIDE INSERTION CC )
Descriptor:Ribonuclease T, DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KB1
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CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A BLUGE DNA (TWO NUCLEOTIDE INSERTION CT )
Descriptor:Ribonuclease T, Bulge DNA, MAGNESIUM ION
Authors:Hsiao, Y.-Y., Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4P5U
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CRYSTAL STRUCTURE OF TATD
Descriptor:Tat-linked quality control protein TatD
Authors:Chen, Y., Li, C.-L., Hsiao, Y.-Y., Duh, Y., Yuan, H.S.
Deposit date:2014-03-20
Release date:2014-08-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
4PE8
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CRYSTAL STRUCTURE OF TATD IN COMPLEX WITH TRINUCLEOTIDE DNA
Descriptor:Tat-linked quality control protein TatD, DNA (5'-D(*GP*CP*T)-3')
Authors:Chen, Y., Li, C.-L., Hsiao, Y.-Y., Duh, Y., Yuan, H.S.
Deposit date:2014-04-23
Release date:2014-08-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
5GYJ
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STRUCTURE OF CATALYTICALLY ACTIVE SORTASE FROM CLOSTRIDIUM DIFFICILE
Descriptor:Putative peptidase C60B, sortase B
Authors:Yin, J.-C., Fei, C.-H., Hsiao, Y.-Y., Nix, J.C., Huang, I.-H., Wang, S.
Deposit date:2016-09-22
Release date:2017-01-04
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural Insights into Substrate Recognition by Clostridium difficile Sortase.
Front Cell Infect Microbiol, 6, 2016
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