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Crystal Structure of Human Anaplastic Lymphoma Kinase in complex with 7-azaindole based inhibitor
Descriptor:	3-[1-(2,5-difluorobenzyl)-1H-pyrazol-4-yl]-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, ALK tyrosine kinase receptor
Authors:	Hosahalli, S, Krishnamurthy, N.R, Lakshminarasimhan, A.
Deposit date:	2013-03-18
Release date:	2013-07-17
Last modified:	2023-11-08
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode Bioorg.Med.Chem.Lett., 23, 2013

CRYSTAL STRUCTURE of PROTEIN TYROSINE PHOSPHATASE 1B IN COMPLEX WITH AN INHIBITOR [(4-{(2S)-2-(1,3-BENZOXAZOL-2-YL)-2-[(4-FLUOROPHENYL)SULFAMOYL]ETHYL}PHENYL)AMINO](OXO)ACETIC ACID
Descriptor:	Tyrosine-protein phosphatase non-receptor type 1, [(4-{(2S)-2-(1,3-benzoxazol-2-yl)-2-[(4-fluorophenyl)sulfamoyl]ethyl}phenyl)amino](oxo)acetic acid
Authors:	Reddy, S.M.V.V.V, Rao, K.N, Subramanya, H.
Deposit date:	2012-12-03
Release date:	2012-12-26
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	X-Ray Structure of PTP1B in Complex with a New PTP1B Inhibitor. Protein Pept.Lett., 21, 2014