Author results

6MHT
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TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET
Descriptor:DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:Cheng, X.
Deposit date:1998-08-05
Release date:1998-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.
Nucleic Acids Res., 25, 1997
3PVI
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D34G MUTANT OF PVUII ENDONUCLEASE COMPLEXED WITH COGNATE DNA SHOWS THAT ASP34 IS DIRECTLY INVOLVED IN DNA RECOGNITION AND INDIRECTLY INVOLVED IN CATALYSIS
Descriptor:DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII ENDONUCLEASE)
Authors:Horton, J.R., Cheng, X.
Deposit date:1998-10-09
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Asp34 of PvuII endonuclease is directly involved in DNA minor groove recognition and indirectly involved in catalysis.
J.Mol.Biol., 284, 1998
7MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor:5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', 5'-D(P*CP*CP*AP*TP*GP*AP*GP*CP*TP*GP*AP*C)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Deposit date:1998-08-05
Release date:1998-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
8MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor:5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Deposit date:1998-08-06
Release date:1998-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
9MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor:5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Deposit date:1998-08-07
Release date:1998-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
1BM8
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DNA-BINDING DOMAIN OF MBP1
Descriptor:TRANSCRIPTION FACTOR MBP1
Authors:Xu, R.-M., Koch, C., Liu, Y., Horton, J.R., Knapp, D., Nasmyth, K., Cheng, X.
Deposit date:1998-07-29
Release date:1999-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis.
Structure, 5, 1997
2PVI
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PVUII ENDONUCLEASE COMPLEXED TO AN IODINATED COGNATE DNA
Descriptor:DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*(C38)P*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII
Authors:Horton, J., Cheng, X.
Deposit date:1998-11-01
Release date:1999-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:How is modification of the DNA substrate recognized by the PvuII restriction endonuclease?
J.Biol.Chem., 379, 1998
1EYU
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HIGH RESOLUTION STRUCTURE OF THE PVUII ENDONCULEASE/COGNATE DNA COMPLEX AT PH 4.6
Descriptor:DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII
Authors:Horton, J.R., Cheng, X.
Deposit date:2000-05-09
Release date:2000-07-21
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:PvuII endonuclease contains two calcium ions in active sites.
J.Mol.Biol., 300, 2000
1F0O
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PVUII ENDONUCLEASE/COGNATE DNA COMPLEX (GLUTARALDEHYDE-CROSSLINKED CRYSTAL) AT PH 7.5 WITH TWO CALCIUM IONS AT EACH ACTIVE SITE
Descriptor:(5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C-3'), TYPE II RESTRICTION ENZYME PVUII, CALCIUM ION
Authors:Horton, J.R., Cheng, X.
Deposit date:2000-05-16
Release date:2000-11-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:PvuII endonuclease contains two calcium ions in active sites.
J.Mol.Biol., 300, 2000
1JQD
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN HISTAMINE METHYLTRANSFERASE (THR105 POLYMORPHIC VARIANT) COMPLEXED WITH ADOHCY AND HISTAMINE
Descriptor:Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, HISTAMINE
Authors:Horton, J.R., Sawada, K., Nishibori, M., Zhang, X., Cheng, X.
Deposit date:2001-08-06
Release date:2002-08-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1JQE
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN HISTAMINE METHYLTRANSFERASE (ILE105 POLYMORPHIC VARIANT) COMPLEXED WITH ADOHCY AND ANTIMALARIAL DRUG QUINACRINE
Descriptor:Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, QUINACRINE, ...
Authors:Horton, J.R., Sawada, K., Nishibori, M., Zhang, X., Cheng, X.
Deposit date:2001-08-06
Release date:2002-08-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
1MOZ
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ADP-RIBOSYLATION FACTOR-LIKE 1 (ARL1) FROM SACCHAROMYCES CEREVISIAE
Descriptor:ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE
Authors:Amor, J.C., Horton, J.R., Zhu, X., Wang, Y., Sullards, C., Ringe, D., Cheng, X., Kahn, R.A.
Deposit date:2002-09-10
Release date:2002-10-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structures of Yeast ARF2 and ARL1: DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
1ML9
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STRUCTURE OF THE NEUROSPORA SET DOMAIN PROTEIN DIM-5, A HISTONE LYSINE METHYLTRANSFERASE
Descriptor:Histone H3 methyltransferase DIM-5, ZINC ION, UNKNOWN
Authors:Zhang, X., Tamaru, H., Khan, S.I., Horton, J.R., Keefe, L.J., Selker, E.U., Cheng, X.
Deposit date:2002-08-30
Release date:2002-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
Cell(Cambridge,Mass.), 111, 2002
1MR3
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SACCHAROMYCES CEREVISIAE ADP-RIBOSYLATION FACTOR 2 (SCARF2) COMPLEXED WITH GDP-3'P AT 1.6A RESOLUTION
Descriptor:ADP-ribosylation factor 2, MAGNESIUM ION, GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, ...
Authors:Amor, J.-C., Horton, J.R., Zhu, X., Wang, Y., Sullards, C., Ringe, D., Cheng, X., Kahn, R.A.
Deposit date:2002-09-17
Release date:2002-11-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of yeast ARF2 and ARL1: distinct roles for the N terminus in the structure and function of ARF family GTPases.
J.Biol.Chem., 276, 2001
1PEG
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STRUCTURAL BASIS FOR THE PRODUCT SPECIFICITY OF HISTONE LYSINE METHYLTRANSFERASES
Descriptor:histone H3 methyltransferase DIM-5, Histone H3, ZINC ION, ...
Authors:Zhang, X., Yang, Z., Khan, S.I., Horton, J.R., Tamaru, H., Selker, E.U., Cheng, X.
Deposit date:2003-05-21
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
1Q0S
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BINARY STRUCTURE OF T4DAM WITH ADOHCY
Descriptor:DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yang, Z., Horton, J.R., Zhou, L., Zhang, X.J., Dong, A., Zhang, X., Schlagman, S.L., Kossykh, V., Hattman, S., Cheng, X.
Deposit date:2003-07-17
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
1Q0T
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TERNARY STRUCTURE OF T4DAM WITH ADOHCY AND DNA
Descriptor:5'-D(*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*T)-3', DNA adenine methylase, IODIDE ION, ...
Authors:Yang, Z., Horton, J.R., Zhou, L., Zhang, X.J., Dong, A., Zhang, X., Schlagman, S.L., Kossykh, V., Hattman, S., Cheng, X.
Deposit date:2003-07-17
Release date:2003-09-23
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
1SKM
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HHAI METHYLTRANSFERASE IN COMPLEX WITH DNA CONTAINING AN ABASIC SOUTH CARBOCYCLIC SUGAR AT ITS TARGET SITE
Descriptor:5'-D(*TP*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(*T*GP*TP*CP*AP*GP*(HCX)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ...
Authors:Horton, J.R., Ratner, G., Banavali, N., Huang, N., Marquez, V.E., MacKerell, A.D., Cheng, X.
Deposit date:2004-03-05
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase
Nucleic Acids Res., 32, 2004
1U2Z
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CRYSTAL STRUCTURE OF HISTONE K79 METHYLTRANSFERASE DOT1P FROM YEAST
Descriptor:Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Sawada, K., Yang, Z., Horton, J.R., Collins, R.E., Zhang, X., Cheng, X.
Deposit date:2004-07-20
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
1YNM
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CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE HINP1I
Descriptor:R.HinP1I restriction endonuclease
Authors:Yang, Z., Horton, J.R., Maunus, R., Wilson, G.G., Roberts, R.J., Cheng, X.
Deposit date:2005-01-24
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI
Nucleic Acids Res., 33, 2005
1YF3
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T4DAM IN COMPLEX WITH ADOHCY AND 13-MER OLIGONUCLEOTIDE MAKING NON- AND SEMI-SPECIFIC (~1/4) CONTACT
Descriptor:5'-D(*AP*CP*CP*AP*TP*GP*AP*TP*CP*TP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*CP*AP*TP*GP*G)-3', DNA adenine methylase, ...
Authors:Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X.
Deposit date:2004-12-30
Release date:2005-05-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
1YFJ
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T4DAM IN COMPLEX WITH ADOHCY AND 15-MER OLIGONUCLEOTIDE SHOWING SEMI-SPECIFIC AND SPECIFIC CONTACT
Descriptor:5'-D(*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*G)-3', DNA adenine methylase, CHLORIDE ION, ...
Authors:Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X.
Deposit date:2005-01-02
Release date:2005-05-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
1YFL
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T4DAM IN COMPLEX WITH SINEFUNGIN AND 16-MER OLIGONUCLEOTIDE SHOWING SEMI-SPECIFIC AND SPECIFIC CONTACT AND FLIPPED BASE
Descriptor:5'-D(P*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*GP*A)-3', DNA adenine methylase, SINEFUNGIN
Authors:Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X.
Deposit date:2005-01-03
Release date:2005-05-17
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
2BZG
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CRYSTAL STRUCTURE OF THIOPURINE S-METHYLTRANSFERASE.
Descriptor:THIOPURINE S-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Battaile, K.P., Wu, H., Zeng, H., Loppnau, P., Dong, A., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2005-08-17
Release date:2005-08-25
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural Basis of Allele Variation of Human Thiopurine-S-Methyltransferase.
Proteins, 67, 2007
2AOT
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HISTAMINE METHYLTRANSFERASE COMPLEXED WITH THE ANTIHISTAMINE DRUG DIPHENHYDRAMINE
Descriptor:Histamine N-methyltransferase, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Horton, J.R., Sawada, K., Nishibori, M., Cheng, X.
Deposit date:2005-08-14
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
170172
PDB entries from 2020-10-21