6MHT | |
3PVI | |
7MHT | | CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX | | Descriptor: | 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', 5'-D(P*CP*CP*AP*TP*GP*AP*GP*CP*TP*GP*AP*C)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... | | Authors: | O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X. | | Deposit date: | 1998-08-05 | | Release date: | 1998-11-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
|
|
8MHT | | CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX | | Descriptor: | 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... | | Authors: | O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X. | | Deposit date: | 1998-08-06 | | Release date: | 1998-11-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
|
|
9MHT | | CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX | | Descriptor: | 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... | | Authors: | O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X. | | Deposit date: | 1998-08-07 | | Release date: | 1998-12-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
|
|
1BM8 | | DNA-BINDING DOMAIN OF MBP1 | | Descriptor: | TRANSCRIPTION FACTOR MBP1 | | Authors: | Xu, R.-M., Koch, C., Liu, Y., Horton, J.R., Knapp, D., Nasmyth, K., Cheng, X. | | Deposit date: | 1998-07-29 | | Release date: | 1999-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis.
Structure, 5, 1997
|
|
2PVI | | PVUII ENDONUCLEASE COMPLEXED TO AN IODINATED COGNATE DNA | | Descriptor: | DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*(C38)P*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII | | Authors: | Horton, J., Cheng, X. | | Deposit date: | 1998-11-01 | | Release date: | 1999-12-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | How is modification of the DNA substrate recognized by the PvuII restriction endonuclease?
J.Biol.Chem., 379, 1998
|
|
1EYU | |
1F0O | |
1JQD | | CRYSTAL STRUCTURE ANALYSIS OF HUMAN HISTAMINE METHYLTRANSFERASE (THR105 POLYMORPHIC VARIANT) COMPLEXED WITH ADOHCY AND HISTAMINE | | Descriptor: | Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, HISTAMINE | | Authors: | Horton, J.R., Sawada, K., Nishibori, M., Zhang, X., Cheng, X. | | Deposit date: | 2001-08-06 | | Release date: | 2002-08-06 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
|
|
1JQE | | CRYSTAL STRUCTURE ANALYSIS OF HUMAN HISTAMINE METHYLTRANSFERASE (ILE105 POLYMORPHIC VARIANT) COMPLEXED WITH ADOHCY AND ANTIMALARIAL DRUG QUINACRINE | | Descriptor: | Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, QUINACRINE, ... | | Authors: | Horton, J.R., Sawada, K., Nishibori, M., Zhang, X., Cheng, X. | | Deposit date: | 2001-08-06 | | Release date: | 2002-08-06 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.
Structure, 9, 2001
|
|
1MOZ | | ADP-RIBOSYLATION FACTOR-LIKE 1 (ARL1) FROM SACCHAROMYCES CEREVISIAE | | Descriptor: | ADP-ribosylation factor-like protein 1, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Amor, J.C., Horton, J.R., Zhu, X., Wang, Y., Sullards, C., Ringe, D., Cheng, X., Kahn, R.A. | | Deposit date: | 2002-09-10 | | Release date: | 2002-10-09 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Structures of Yeast ARF2 and ARL1:
DISTINCT ROLES FOR THE N TERMINUS IN THE STRUCTURE
AND FUNCTION OF ARF FAMILY GTPases
J.Biol.Chem., 276, 2001
|
|
1ML9 | | STRUCTURE OF THE NEUROSPORA SET DOMAIN PROTEIN DIM-5, A HISTONE LYSINE METHYLTRANSFERASE | | Descriptor: | Histone H3 methyltransferase DIM-5, ZINC ION, UNKNOWN | | Authors: | Zhang, X., Tamaru, H., Khan, S.I., Horton, J.R., Keefe, L.J., Selker, E.U., Cheng, X. | | Deposit date: | 2002-08-30 | | Release date: | 2002-10-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure of the Neurospora SET domain protein DIM-5,
a histone H3 lysine methyltransferase
Cell(Cambridge,Mass.), 111, 2002
|
|
1MR3 | | SACCHAROMYCES CEREVISIAE ADP-RIBOSYLATION FACTOR 2 (SCARF2) COMPLEXED WITH GDP-3'P AT 1.6A RESOLUTION | | Descriptor: | ADP-ribosylation factor 2, MAGNESIUM ION, GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, ... | | Authors: | Amor, J.-C., Horton, J.R., Zhu, X., Wang, Y., Sullards, C., Ringe, D., Cheng, X., Kahn, R.A. | | Deposit date: | 2002-09-17 | | Release date: | 2002-11-20 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structures of yeast ARF2 and ARL1: distinct roles for the N terminus in the structure and function of ARF family GTPases.
J.Biol.Chem., 276, 2001
|
|
1PEG | | STRUCTURAL BASIS FOR THE PRODUCT SPECIFICITY OF HISTONE LYSINE METHYLTRANSFERASES | | Descriptor: | histone H3 methyltransferase DIM-5, Histone H3, ZINC ION, ... | | Authors: | Zhang, X., Yang, Z., Khan, S.I., Horton, J.R., Tamaru, H., Selker, E.U., Cheng, X. | | Deposit date: | 2003-05-21 | | Release date: | 2003-08-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structural basis for the product specificity of histone lysine methyltransferases
Mol.Cell, 12, 2003
|
|
1Q0S | | BINARY STRUCTURE OF T4DAM WITH ADOHCY | | Descriptor: | DNA adenine methylase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Yang, Z., Horton, J.R., Zhou, L., Zhang, X.J., Dong, A., Zhang, X., Schlagman, S.L., Kossykh, V., Hattman, S., Cheng, X. | | Deposit date: | 2003-07-17 | | Release date: | 2003-09-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
|
|
1Q0T | | TERNARY STRUCTURE OF T4DAM WITH ADOHCY AND DNA | | Descriptor: | 5'-D(*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*T)-3', DNA adenine methylase, IODIDE ION, ... | | Authors: | Yang, Z., Horton, J.R., Zhou, L., Zhang, X.J., Dong, A., Zhang, X., Schlagman, S.L., Kossykh, V., Hattman, S., Cheng, X. | | Deposit date: | 2003-07-17 | | Release date: | 2003-09-23 | | Last modified: | 2020-07-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of the bacteriophage T4 DNA adenine methyltransferase
Nat.Struct.Biol., 10, 2003
|
|
1SKM | | HHAI METHYLTRANSFERASE IN COMPLEX WITH DNA CONTAINING AN ABASIC SOUTH CARBOCYCLIC SUGAR AT ITS TARGET SITE | | Descriptor: | 5'-D(*TP*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(*T*GP*TP*CP*AP*GP*(HCX)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ... | | Authors: | Horton, J.R., Ratner, G., Banavali, N., Huang, N., Marquez, V.E., MacKerell, A.D., Cheng, X. | | Deposit date: | 2004-03-05 | | Release date: | 2004-08-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferase
Nucleic Acids Res., 32, 2004
|
|
1U2Z | | CRYSTAL STRUCTURE OF HISTONE K79 METHYLTRANSFERASE DOT1P FROM YEAST | | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Sawada, K., Yang, Z., Horton, J.R., Collins, R.E., Zhang, X., Cheng, X. | | Deposit date: | 2004-07-20 | | Release date: | 2004-09-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
J.Biol.Chem., 279, 2004
|
|
1YNM | | CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE HINP1I | | Descriptor: | R.HinP1I restriction endonuclease | | Authors: | Yang, Z., Horton, J.R., Maunus, R., Wilson, G.G., Roberts, R.J., Cheng, X. | | Deposit date: | 2005-01-24 | | Release date: | 2005-05-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI
Nucleic Acids Res., 33, 2005
|
|
1YF3 | | T4DAM IN COMPLEX WITH ADOHCY AND 13-MER OLIGONUCLEOTIDE MAKING NON- AND SEMI-SPECIFIC (~1/4) CONTACT | | Descriptor: | 5'-D(*AP*CP*CP*AP*TP*GP*AP*TP*CP*TP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*AP*GP*AP*TP*CP*AP*TP*GP*G)-3', DNA adenine methylase, ... | | Authors: | Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X. | | Deposit date: | 2004-12-30 | | Release date: | 2005-05-17 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
|
|
1YFJ | | T4DAM IN COMPLEX WITH ADOHCY AND 15-MER OLIGONUCLEOTIDE SHOWING SEMI-SPECIFIC AND SPECIFIC CONTACT | | Descriptor: | 5'-D(*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*G)-3', DNA adenine methylase, CHLORIDE ION, ... | | Authors: | Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X. | | Deposit date: | 2005-01-02 | | Release date: | 2005-05-17 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
|
|
1YFL | | T4DAM IN COMPLEX WITH SINEFUNGIN AND 16-MER OLIGONUCLEOTIDE SHOWING SEMI-SPECIFIC AND SPECIFIC CONTACT AND FLIPPED BASE | | Descriptor: | 5'-D(P*TP*CP*AP*CP*AP*GP*GP*AP*TP*CP*CP*TP*GP*TP*GP*A)-3', DNA adenine methylase, SINEFUNGIN | | Authors: | Horton, J.R., Liebert, K., Hattman, S., Jeltsch, A., Cheng, X. | | Deposit date: | 2005-01-03 | | Release date: | 2005-05-17 | | Last modified: | 2020-07-22 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase.
Cell(Cambridge,Mass.), 121, 2005
|
|
2BZG | | CRYSTAL STRUCTURE OF THIOPURINE S-METHYLTRANSFERASE. | | Descriptor: | THIOPURINE S-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | | Authors: | Battaile, K.P., Wu, H., Zeng, H., Loppnau, P., Dong, A., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC) | | Deposit date: | 2005-08-17 | | Release date: | 2005-08-25 | | Last modified: | 2019-05-15 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structural Basis of Allele Variation of Human Thiopurine-S-Methyltransferase.
Proteins, 67, 2007
|
|
2AOT | | HISTAMINE METHYLTRANSFERASE COMPLEXED WITH THE ANTIHISTAMINE DRUG DIPHENHYDRAMINE | | Descriptor: | Histamine N-methyltransferase, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Horton, J.R., Sawada, K., Nishibori, M., Cheng, X. | | Deposit date: | 2005-08-14 | | Release date: | 2005-09-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
|
|
