Author results

4J7I
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SET7/9Y335F IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Horowitz, S., Trievel, R.C.
Deposit date:2013-02-13
Release date:2014-01-08
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.
J.Am.Chem.Soc., 135, 2013
4J83
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SET7/9 IN COMPLEX WITH TAF10K189A PEPTIDE AND ADOMET
Descriptor:Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYLMETHIONINE
Authors:Horowitz, S., Nimtz, J.S., Trievel, R.C.
Deposit date:2013-02-14
Release date:2014-01-08
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.
J.Am.Chem.Soc., 135, 2013
4J8O
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SET7/9 IN COMPLEX WITH TAF10K189A PEPTIDE AND ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Horowitz, S., Trievel, R.C.
Deposit date:2013-02-14
Release date:2014-01-08
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.
J.Am.Chem.Soc., 135, 2013
5WNW
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CHAPERONE SPY BOUND TO IM7 6-45 ENSEMBLE
Descriptor:Periplasmic chaperone Spy, Colicin-E7 immunity protein, IMIDAZOLE, ...
Authors:Horowitz, S., Salmon, L., Koldewey, P., Ahlstrom, L.S., Martin, R., Xu, Q., Afonine, P.V., Trievel, R.C., Brooks, C.L., Bardwell, J.C.A.
Deposit date:2017-08-01
Release date:2017-08-16
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
5WO1
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CHAPERONE SPY H96L BOUND TO IM7 L18A L19A L37A (IM7 UN-MODELED)
Descriptor:Periplasmic chaperone Spy, IMIDAZOLE, ZINC ION, ...
Authors:Horowitz, S., Koldewey, P., Martin, R., Bardwell, J.C.A.
Deposit date:2017-08-01
Release date:2017-08-16
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
5WO2
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CHAPERONE SPY BOUND TO CASEIN FRAGMENT (CASEIN UN-MODELED)
Descriptor:Periplasmic chaperone Spy, IMIDAZOLE, ZINC ION, ...
Authors:Horowitz, S., Koldewey, P., Martin, R., Bardwell, J.C.A.
Deposit date:2017-08-01
Release date:2017-08-16
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
5WO3
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CHAPERONE SPY BOUND TO IM7 (IM7 UN-MODELED)
Descriptor:Periplasmic chaperone Spy, ZINC ION, CHLORIDE ION, ...
Authors:Horowitz, S., Koldewey, P., Martin, R., Bardwell, J.C.A.
Deposit date:2017-08-01
Release date:2017-08-16
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Visualizing chaperone-assisted protein folding.
Nat. Struct. Mol. Biol., 23, 2016
4J7F
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SET7/9Y335PAF IN COMPLEX WITH TAF10 PEPTIDE AND ADOHCY
Descriptor:Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Horowitz, S., Del Rizzo, P.A., Trievel, R.C.
Deposit date:2013-02-13
Release date:2014-03-26
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Methyl CH O Hydrogen Bonds Orchestrate AdoMet-Dependent Methylation
To be Published
5KCI
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CRYSTAL STRUCTURE OF HTC1
Descriptor:Uncharacterized protein YPL067C, ZINC ION, GLYCEROL, ...
Authors:Martin, R.M., Horowitz, S., Koepnick, B., Cooper, S., Flatten, J., Rogawski, D.S., Koropatkin, N.M., Beinlich, F.R.M., Players, F., Students, U.M., Popovic, Z., Baker, D., Khatib, F., Bardwell, J.C.A.
Deposit date:2016-06-06
Release date:2016-09-21
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.833 Å)
Cite:Determining crystal structures through crowdsourcing and coursework.
Nat Commun, 7, 2016
5J7D
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COMPUTATIONALLY DESIGNED THIOREDOXIN DF106
Descriptor:Designed Thioredoxin dF106, COPPER (II) ION
Authors:Horowitz, S., Johansen, N., Olsen, J.G., Winther, J.R.
Deposit date:2016-04-06
Release date:2016-10-05
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone Template.
J.Mol.Biol., 428, 2016
6OWX
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SPY H96L:IM7 L18PI-PHE COMPLEX; MULTIPLE ANOMALOUS DATASETS CONTAINED HEREIN FOR ELEMENT IDENTIFICATION
Descriptor:Periplasmic chaperone Spy, ZINC ION, CHLORIDE ION, ...
Authors:Rocchio, S., Duman, R., El Omari, K., Mykhaylyk, V., Yan, Z., Wagner, A., Bardwell, J.C.A., Horowitz, S.
Deposit date:2019-05-12
Release date:2019-05-29
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Identifying dynamic, partially occupied residues using anomalous scattering
To Be Published
6OWY
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SPY H96L:IM7 K20PI-PHE COMPLEX; MULTIPLE ANOMALOUS DATASETS CONTAINED HEREIN FOR ELEMENT IDENTIFICATION
Descriptor:Periplasmic chaperone Spy, ZINC ION, CHLORIDE ION, ...
Authors:Rocchio, S., Duman, R., El Omari, K., Mykhaylyk, V., Yan, Z., Wagner, A., Bardwell, J.C.A., Horowitz, S.
Deposit date:2019-05-12
Release date:2019-05-29
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Identifying dynamic, partially occupied residues using anomalous scattering
To Be Published
6OWZ
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SPY H96L:IM7 L19PI-PHE COMPLEX; MULTIPLE ANOMALOUS DATASETS CONTAINED HEREIN FOR ELEMENT IDENTIFICATION
Descriptor:Periplasmic chaperone Spy, ZINC ION, CHLORIDE ION, ...
Authors:Rocchio, S., Duman, R., El Omari, K., Mykhaylyk, V., Yan, Z., Wagner, A., Bardwell, J.C.A., Horowitz, S.
Deposit date:2019-05-12
Release date:2019-05-29
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Identifying dynamic, partially occupied residues using anomalous scattering
To Be Published
5EG2
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SET7/9 N265A IN COMPLEX WITH ADOHCY AND TAF10 PEPTIDE
Descriptor:Histone-lysine N-methyltransferase SETD7, Transcription initiation factor TFIID subunit 10, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Kroner, G.M., Fick, R.J., Trievel, R.C.
Deposit date:2015-10-26
Release date:2016-01-13
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Sulfur-Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9.
Acs Chem.Biol., 11, 2016
6M81
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CRYSTAL STRUCTURE OF TYLM1 Y14F BOUND TO SAH AND DTDP-PHENOL
Descriptor:dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine
Authors:Fick, R.J., McDole, B.G., Trievel, R.C.
Deposit date:2018-08-21
Release date:2019-03-13
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (1.782 Å)
Cite:Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
Biochemistry, 58, 2019
6M82
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CRYSTAL STRUCTURE OF TYLM1 Y14PAF BOUND TO SAH AND DTDP-PHENOL
Descriptor:dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ...
Authors:Fick, R.J., McDole, B.G., Trievel, R.C.
Deposit date:2018-08-21
Release date:2019-03-13
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (1.3971 Å)
Cite:Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
Biochemistry, 58, 2019
6M83
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CRYSTAL STRUCTURE OF TYLM1 S120A BOUND TO SAH AND DTDP-PHENOL
Descriptor:dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ...
Authors:Fick, R.J., McDole, B.G., Trievel, R.C.
Deposit date:2018-08-21
Release date:2019-03-13
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (1.3685 Å)
Cite:Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
Biochemistry, 58, 2019