Author results

1LPF
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THREE-DIMENSIONAL STRUCTURE OF LIPOAMIDE DEHYDROGENASE FROM PSEUDOMONAS FLUORESCENS AT 2.8 ANGSTROMS RESOLUTION. ANALYSIS OF REDOX AND THERMOSTABILITY PROPERTIES
Descriptor:DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Mattevi, A., Hol, W.
Deposit date:1992-10-26
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of lipoamide dehydrogenase from Pseudomonas fluorescens at 2.8 A resolution. Analysis of redox and thermostability properties.
J.Mol.Biol., 230, 1993
1HTL
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MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Descriptor:HEAT-LABILE ENTEROTOXIN, SUBUNIT B, SUBUNIT A
Authors:Merritt, E.A., Hol, W.G.J.
Deposit date:1995-02-15
Release date:1995-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
1LT4
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HEAT-LABILE ENTEROTOXIN MUTANT S63K
Descriptor:HEAT-LABILE ENTEROTOXIN, BETA-D-GALACTOSE, BETA-D-GLUCOSE
Authors:Van Den Akker, F., Hol, W.G.J.
Deposit date:1997-04-14
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
1LTG
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THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
Descriptor:HEAT-LABILE ENTEROTOXIN
Authors:Van Den Akker, F., Hol, W.G.J.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
1GYQ
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CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD
Descriptor:PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Suresh, S., Hol, W.
Deposit date:1999-03-05
Release date:1999-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.
Proc.Natl.Acad.Sci.USA, 96, 1999
1MC0
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REGULATORY SEGMENT OF MOUSE 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 2A, CONTAINING THE GAF A AND GAF B DOMAINS
Descriptor:3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE
Authors:Martinez, S., Wu, A., Glavas, N., Tang, X., Turley, S., Hol, W., Beavo, J.
Deposit date:2002-08-04
Release date:2002-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
3K81
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STRUCTURE OF THE CENTRAL INTERACTION PROTEIN FROM THE TRYPANOSOMA BRUCEI EDITOSOME IN COMPLEX WITH SINGLE DOMAIN ANTIBODIES
Descriptor:MP18 RNA editing complex protein, Single strand antibody VHH domain
Authors:Park, Y.-J., Hol, W.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
3STB
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A COMPLEX OF TWO EDITOSOME PROTEINS AND TWO NANOBODIES
Descriptor:single domain antibody VHH, RNA-editing complex protein MP42, MP18 RNA editing complex protein
Authors:Park, Y.-J., Hol, W.
Deposit date:2011-07-09
Release date:2011-11-02
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody.
Nucleic Acids Res., 40, 2012
4DK3
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STRUCTURE OF EDITOSOME PROTEIN
Descriptor:single domain antibody VHH, RNA-editing complex protein MP81
Authors:Park, Y.-J., Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
4DK6
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STRUCTURE OF EDITOSOME PROTEIN
Descriptor:single domain antibody VHH, RNA-editing complex protein MP81
Authors:Park, Y.-J., Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
4DKA
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STRUCTURE OF EDITOSOME PROTEIN
Descriptor:single domain antibody VHH, RNA-editing complex protein MP81, SODIUM ION
Authors:Park, Y.-J., Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
4DNI
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STRUCTURE OF EDITOSOME PROTEIN
Descriptor:Fusion protein of RNA-editing complex proteins MP42 and MP18
Authors:Park, Y.-J., Hol, W.
Deposit date:2012-02-08
Release date:2012-12-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds.
J.Struct.Biol., 180, 2012
4PHT
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ATPASE GSPE IN COMPLEX WITH THE CYTOPLASMIC DOMAIN OF GSPL FROM THE VIBRIO VULNIFICUS TYPE II SECRETION SYSTEM
Descriptor:Type II secretion system protein L, General secretory pathway protein E, ZINC ION, ...
Authors:Lu, C., Korotkov, K., Hol, W.
Deposit date:2014-05-06
Release date:2014-11-26
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Crystal structure of the full-length ATPase GspE from the Vibrio vulnificus type II secretion system in complex with the cytoplasmic domain of GspL.
J.Struct.Biol., 187, 2014
1SKZ
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PROTEASE INHIBITOR
Descriptor:ANTISTASIN, CHLORIDE ION
Authors:Krengel, U., Dijkstra, B.W.
Deposit date:1997-04-16
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structure of antistasin at 1.9 A resolution and its modelled complex with blood coagulation factor Xa.
EMBO J., 16, 1997