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1GQ6
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PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS
Descriptor:PROCLAVAMINATE AMIDINO HYDROLASE, MANGANESE (II) ION
Authors:Elkins, J.M., Clifton, I.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Hewitson, K.S.
Deposit date:2001-11-20
Release date:2002-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Oligomeric Structure of Proclavaminic Acid Amidino Hydrolase: Evolution of a Hydrolytic Enzyme in Clavulanic Acid Biosynthesis
Biochem.J., 366, 2002
1GQ7
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PROCLAVAMINATE AMIDINO HYDROLASE FROM STREPTOMYCES CLAVULIGERUS
Descriptor:PROCLAVAMINATE AMIDINO HYDROLASE, MANGANESE (II) ION
Authors:Elkins, J.M., Clifton, I.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Hewitson, K.S.
Deposit date:2001-11-20
Release date:2002-06-06
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.
Biochem. J., 366, 2002
2JAH
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BIOCHEMICAL AND STRUCTURAL ANALYSIS OF THE CLAVULANIC ACID DEHYDEOGENASE (CAD) FROM STREPTOMYCES CLAVULIGERUS
Descriptor:CLAVULANIC ACID DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:MacKenzie, A.K., Kershaw, N.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Andersson, I.
Deposit date:2006-11-28
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid
Biochemistry, 46, 2007
2JAP
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CLAVULANIC ACID DEHYDROGENASE: STRUCTURAL AND BIOCHEMICAL ANALYSIS OF THE FINAL STEP IN THE BIOSYNTHESIS OF THE BETA-LACTAMASE INHIBITOR CLAVULANIC ACID
Descriptor:CLAVALDEHYDE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID
Authors:MacKenzie, A.K., Kershaw, N.J., Hernandez, H., Robinson, C.V., Schofield, C.J., Andersson, I.
Deposit date:2006-11-29
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Clavulanic Acid Dehydrogenase: Structural and Biochemical Analysis of the Final Step in the Biosynthesis of the Beta-Lactamase Inhibitor Clavulanic Acid
Biochemistry, 46, 2007
2VRD
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THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C
Descriptor:U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION
Authors:Muto, Y., Pomeranz-Krummel, D., Oubridge, C., Hernandez, H., Robinson, C., Neuhaus, D., Nagai, K.
Deposit date:2008-03-31
Release date:2008-04-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C
J.Mol.Biol., 341, 2004
6FO1
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HUMAN R2TP SUBCOMPLEX CONTAINING 1 RUVBL1-RUVBL2 HEXAMER BOUND TO 1 RBD DOMAIN FROM RPAP3.
Descriptor:RuvB-like 1, RuvB-like 2, RNA polymerase II-associated protein 3, ...
Authors:Martino, F., Munoz-Hernandez, H., Rodriguez, C.F., Pearl, L.H., Llorca, O.
Deposit date:2018-02-05
Release date:2018-04-04
Last modified:2018-05-30
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
6QI8
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TRUNCATED HUMAN R2TP COMPLEX, STRUCTURE 3 (ADP-FILLED)
Descriptor:RuvB-like 1, RuvB-like 2, ADENOSINE-5'-DIPHOSPHATE
Authors:Munoz-Hernandez, H., Rodriguez, C.F., Llorca, O.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM
Sci Adv, 2019
5D6C
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STRUCTURE OF 4497 FAB BOUND TO SYNTHETIC WALL TEICHOIC ACID FRAGMENT
Descriptor:4497 antibody IgK (VL and CL), 4497 antibody IgG1 (VH and CH1), CALCIUM ION, ...
Authors:Lupardus, P.J., Fong, R.
Deposit date:2015-08-12
Release date:2015-11-11
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Novel antibody-antibiotic conjugate eliminates intracellular S. aureus.
Nature, 527, 2015
2K0A
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1H, 15N AND 13C CHEMICAL SHIFT ASSIGNMENTS FOR RDS3 PROTEIN
Descriptor:Pre-mRNA-splicing factor RDS3, ZINC ION
Authors:Loening, N., van Roon, A., Yang, J., Nagai, K., Neuhaus, D.
Deposit date:2008-01-31
Release date:2008-07-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3KL4
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RECOGNITION OF A SIGNAL PEPTIDE BY THE SIGNAL RECOGNITION PARTICLE
Descriptor:Signal recognition 54 kDa protein, Signal peptide of yeast dipeptidyl aminopeptidase B
Authors:Janda, C.Y., Nagai, K., Li, J., Oubridge, C.
Deposit date:2009-11-06
Release date:2010-03-31
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Recognition of a signal peptide by the signal recognition particle.
Nature, 465, 2010
5NJH
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TRIAZOLOPYRIMIDINES STABILIZE MICROTUBULES BY BINDING TO THE VINCA INHIBITOR SITE OF TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Sharma, A., Calvo, G.S., Prota, A.E., Diaz, J.F., Steinmetz, M.O.
Deposit date:2017-03-28
Release date:2017-06-21
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin.
Cell Chem Biol, 24, 2017
1JNJ
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NMR SOLUTION STRUCTURE OF THE HUMAN BETA2-MICROGLOBULIN
Descriptor:beta2-microglobulin
Authors:Verdone, G., Corazza, A., Viglino, P., Pettirossi, F., Giorgetti, S., Mangione, P., Andreola, A., Stoppini, M., Bellotti, V., Esposito, G.
Deposit date:2001-07-24
Release date:2002-02-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
3CW1
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CRYSTAL STRUCTURE OF HUMAN SPLICEOSOMAL U1 SNRNP
Descriptor:U1 snRNA, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B, ...
Authors:Pomeranz Krummel, D.A., Oubridge, C., Leung, A.K., Li, J., Nagai, K.
Deposit date:2008-04-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (5.493 Å)
Cite:Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
Nature, 458, 2009