Author results

4G6U
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CDIA-CT/CDII TOXIN AND IMMUNITY COMPLEX FROM ESCHERICHIA COLI
Descriptor:EC869 CdiA-CT, EC869 CdiI, ZINC ION, ...
Authors:Morse, R.P., Nikolakakis, K., Willet, J., Gerrick, E., Low, D.A., Hayes, C.S., Goulding, C.W.
Deposit date:2012-07-19
Release date:2012-12-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
4G6V
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CDIA-CT/CDII TOXIN AND IMMUNITY COMPLEX FROM BURKHOLDERIA PSEUDOMALLEI
Descriptor:Adhesin/hemolysin, CdiI, BROMIDE ION
Authors:Morse, R.P., Nikolakakis, K., Willet, J., Gerrick, E., Low, D.A., Hayes, C.S., Goulding, C.W.
Deposit date:2012-07-19
Release date:2012-12-12
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
4Q7O
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THE CRYSTAL STRUCTURE OF AN IMMUNITY PROTEIN NMB0503 FROM NEISSERIA MENINGITIDIS MC58
Descriptor:Immunity protein, BROMIDE ION, FORMIC ACID
Authors:Tan, K., Stols, L., Eschenfeldt, W., Babnigg, G., Low, D.A., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2014-04-25
Release date:2014-05-14
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58.
Acta Crystallogr F Struct Biol Commun, 71, 2015
5I4Q
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CONTACT-DEPENDENT INHIBITION SYSTEM FROM ESCHERICHIA COLI NC101 - TERNARY CDIA/CDII/EF-TU COMPLEX (DOMAINS 2 AND 3)
Descriptor:Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
5I4R
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CONTACT-DEPENDENT INHIBITION SYSTEM FROM ESCHERICHIA COLI NC101 - TERNARY CDIA/CDII/EF-TU COMPLEX (TRYPSIN-MODIFIED)
Descriptor:Contact-dependent inhibitor A, Elongation factor Tu, Contact-dependent inhibitor I, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2016-02-12
Release date:2017-06-28
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
5T86
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CRYSTAL STRUCTURE OF CDI COMPLEX FROM E. COLI A0 34/86
Descriptor:CdiA toxin, CdiI immunity protein, ACETATE ION
Authors:Michalska, K., Stols, L., Jedrzejczak, R., Hayes, C.S., Goulding, C.W., Joachimiak, A., Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG)
Deposit date:2016-09-06
Release date:2017-09-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of CDI complex from E. coli A0 34/86
To Be Published
5T87
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CRYSTAL STRUCTURE OF CDI COMPLEX FROM CUPRIAVIDUS TAIWANENSIS LMG 19424
Descriptor:CdiI immunity protein, CdiA toxin
Authors:Michalska, K., Joachimiak, G., Jedrzejczak, R., Hayes, C.S., Goulding, C.W., Joachimiak, A., Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG)
Deposit date:2016-09-06
Release date:2017-09-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Proteins, 86 Suppl 1, 2018
6CP8
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CONTACT-DEPENDENT GROWTH INHIBITION TOXIN-IMMUNITY PROTEIN COMPLEX FROM FROM E. COLI 3006
Descriptor:CdiA, CdiI, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2018-03-13
Release date:2019-03-13
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006
To Be Published
6CP9
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CONTACT-DEPENDENT GROWTH INHIBITION TOXIN - IMMUNITY PROTEIN COMPLEX FROM KLEBSIELLA PNEUMONIAE 342
Descriptor:CdiA, CdiI
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2018-03-13
Release date:2019-03-13
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Contact-dependent growth inhibition toxin - immunity protein complex from Klebsiella pneumoniae 342
To Be Published
4NTQ
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CDIA-CT/CDII TOXIN AND IMMUNITY COMPLEX FROM ENTEROBACTER CLOACAE
Descriptor:Contact-dependent inhibitor A, ECL CdiI
Authors:Morse, R.P., Goulding, C.W.
Deposit date:2013-12-02
Release date:2014-03-26
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CdiA from Enterobacter cloacae Delivers a Toxic Ribosomal RNase into Target Bacteria.
Structure, 22, 2014
4ZQU
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CDIA-CT/CDII TOXIN AND IMMUNITY COMPLEX FROM YERSINIA PSEUDOTUBERCULOSIS
Descriptor:CdiA-CT toxin, Conserved domain protein, CdiI toxin, ...
Authors:Morse, R.P., Johnson, P.M., Credali, A., Goulding, C.W.
Deposit date:2015-05-11
Release date:2015-10-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Diversification of beta-Augmentation Interactions between CDI Toxin/Immunity Proteins.
J.Mol.Biol., 427, 2015
4ZQV
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CDII IMMUNITY PROTEIN FROM YERSINIA KRISTENSENII
Descriptor:CdiI Immunity protein
Authors:Morse, R.P., Goulding, C.W.
Deposit date:2015-05-11
Release date:2015-10-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Diversification of beta-Augmentation Interactions between CDI Toxin/Immunity Proteins.
J.Mol.Biol., 427, 2015
4ZQW
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CDII FROM ESCHERICHIA COLI EC869 IN COMPLEX WITH A MACROCYCLIC PEPTIDE
Descriptor:Immunity protein CdiI-o11, macrocyclic peptide, CHLORIDE ION
Authors:Morse, R.P., Goulding, C.W.
Deposit date:2015-05-11
Release date:2015-10-28
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Diversification of beta-Augmentation Interactions between CDI Toxin/Immunity Proteins.
J.Mol.Biol., 427, 2015
5E3E
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CRYSTAL STRUCTURE OF CDIA-CT/CDII COMPLEX FROM Y. KRISTENSENII 33638
Descriptor:CdiI immunity protein, Large exoprotein involved in heme utilization or adhesion, SODIUM ION
Authors:Michalska, K., Joachimiak, G., Jedrzejczak, R., Goulding, C.W., Joachimiak, A., Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG)
Deposit date:2015-10-02
Release date:2015-11-25
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily.
Nucleic Acids Res., 45, 2017
5J43
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CDIA-CT FROM UROPATHOGENIC ESCHERICHIA COLI IN COMPLEX WITH CYSK
Descriptor:Cysteine synthase A, tRNA nuclease CdiA
Authors:Morse, R.P., Goulding, C.W., Johnson, P.M.
Deposit date:2016-03-31
Release date:2016-07-27
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Unraveling the essential role of CysK in CDI toxin activation.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5J4A
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CDIA-CT TOXIN FROM BURKHOLDERIA PSEUDOMALLEI E479 IN COMPLEX WITH COGNATE CDII IMMUNITY PROTEIN
Descriptor:tRNA nuclease CdiA, Immunity protein CdiI
Authors:Goulding, C.W., Johnson, P.M.
Deposit date:2016-03-31
Release date:2016-07-27
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Functional Diversity of Cytotoxic tRNase/Immunity Protein Complexes from Burkholderia pseudomallei.
J.Biol.Chem., 291, 2016
5J5V
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CDIA-CT FROM UROPATHOGENIC ESCHERICHIA COLI IN COMPLEX WITH COGNATE IMMUNITY PROTEIN AND CYSK
Descriptor:Cysteine synthase A, tRNA nuclease CdiA, Immunity protein CdiI
Authors:Goulding, C.W., Johnson, P.M., Morse, R.P.
Deposit date:2016-04-04
Release date:2016-07-27
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Unraveling the essential role of CysK in CDI toxin activation.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016