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2HT5
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N8 NEURAMINIDASE
Descriptor:Neuraminidase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, CALCIUM ION
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT7
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N8 NEURAMINIDASE IN OPEN COMPLEX WITH OSELTAMIVIR
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HT8
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N8 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-25
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTQ
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N8 NEURAMINIDASE IN COMPLEX WITH ZANAMIVIR
Descriptor:Neuraminidase, ZANAMIVIR
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTR
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N8 NEURAMINIDASE IN COMPLEX WITH DANA
Descriptor:Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTU
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N8 NEURAMINIDASE IN COMPLEX WITH PERAMIVIR
Descriptor:Neuraminidase, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTV
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N4 NEURAMINIDASE
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTW
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N4 NEURAMINIDASE IN COMPLEX WITH DANA
Descriptor:Neuraminidase, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HTY
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N1 NEURAMINIDASE
Descriptor:Neuraminidase, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, CALCIUM ION, ...
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU0
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 1
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU4
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N1 NEURAMINIDASE IN COMPLEX WITH OSELTAMIVIR 2
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Russell, R.J., Haire, L.F., Stevens, D.J., Collins, P.J., Lin, Y.P., Blackburn, G.M., Hay, A.J., Gamblin, S.J., Skehel, J.J.
Deposit date:2006-07-26
Release date:2006-09-05
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2YP2
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP3
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP4
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP5
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HAEMAGGLUTININ OF 2004 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP7
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP8
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE 6SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YP9
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HAEMAGGLUTININ OF 2005 HUMAN H3N2 VIRUS IN COMPLEX WITH AVIAN RECEPTOR ANALOGUE 3SLN
Descriptor:HEMAGGLUTININ, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Xiong, X., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Liu, J., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-29
Release date:2012-11-07
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
2YPG
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HAEMAGGLUTININ OF 1968 HUMAN H3N2 VIRUS IN COMPLEX WITH HUMAN RECEPTOR ANALOGUE LSTC
Descriptor:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, J., Xiong, X., Haire, L.F., Lin, Y.P., Wharton, S.A., Martin, S.R., Coombs, P.J., Vachieri, S.G., Christodoulou, E., Walker, P.A., Skehel, J.J., Gamblin, S.J., Hay, A.J., Daniels, R.S., McCauley, J.W.
Deposit date:2012-10-30
Release date:2012-11-07
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CKZ
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N1 NEURAMINIDASE H274Y + ZANAMIVIR
Descriptor:Neuraminidase, CALCIUM ION, ZANAMIVIR
Authors:Colllins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL0
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N1 NEURAMINIDASE H274Y + OSELTAMIVIR
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION
Authors:Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
3CL2
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N1 NEURAMINIDASE N294S + OSELTAMIVIR
Descriptor:Neuraminidase, (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid
Authors:Collins, P., Haire, L.F., Lin, Y.P., Liu, J., Russell, R.J., Walker, P.A., Skehel, J.J., Martin, S.R., Hay, A.J., Gamblin, S.J.
Deposit date:2008-03-18
Release date:2008-05-20
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.538 Å)
Cite:Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
4B7J
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H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:van der Vries, E., Vachieri, S.G., Xiong, X., Liu, J., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-20
Release date:2012-10-03
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.417 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B7M
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H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION, ...
Authors:van der Vries, E., Vachieri, S.G., Xiong, X., Liu, J., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
4B7N
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H1N1 2009 PANDEMIC INFLUENZA VIRUS: RESISTANCE OF THE I223R NEURAMINIDASE MUTANT EXPLAINED BY KINETIC AND STRUCTURAL ANALYSIS
Descriptor:NEURAMINIDASE, N-ACETYL-D-GLUCOSAMINE, ZANAMIVIR, ...
Authors:van der Vries, E., Vachieri, S.G., Xiong, X., Liu, J., Collins, P.J., Walker, P.A., Haire, L.F., Hay, A.J., Schutten, M., Osterhaus, A.D.M.E., Martin, S.R., Boucher, C.A.B., Skehel, J.J., Gamblin, S.J.
Deposit date:2012-08-21
Release date:2012-10-03
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:H1N1 2009 Pandemic Influenza Virus: Resistance of the I223R Neuraminidase Mutant Explained by Kinetic and Structural Analysis
Plos Pathog., 8, 2012
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