Author results

1BOY
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EXTRACELLULAR REGION OF HUMAN TISSUE FACTOR
Descriptor:HUMAN TISSUE FACTOR
Authors:Boys, C.W.G., Tuddenham, E.G.D., Harlos, K.
Deposit date:1996-01-11
Release date:1996-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the extracellular region of human tissue factor.
Nature, 370, 1994
4UOI
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UNEXPECTED STRUCTURE FOR THE N-TERMINAL DOMAIN OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E1
Descriptor:GENOME POLYPROTEIN, N-ACETYL-D-GLUCOSAMINE
Authors:El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.
Deposit date:2014-06-04
Release date:2014-08-20
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Unexpected Structure for the N-Terminal Domain of Hepatitis C Virus Envelope Glycoprotein E1
Acta Crystallogr.,Sect.D, 70, 2014
1E5H
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DELTA-R307A DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH SUCCINATE AND CARBON DIOXIDE
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, SUCCINIC ACID, ...
Authors:Lee, H.J., Lloyd, M.D., Harlos, K., Clifton, I.J., Baldwin, J.E., Schofield, C.J.
Deposit date:2000-07-26
Release date:2001-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs)
J.Mol.Biol., 308, 2001
1E5I
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DELTA-R306 DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH IRON AND 2-OXOGLUTARATE.
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXOGLUTARIC ACID
Authors:Lee, H.J., Lloyd, M.D., Harlos, K., Clifton, I.J., Baldwin, J.E., Schofield, C.J.
Deposit date:2000-07-26
Release date:2001-07-26
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs)
J.Mol.Biol., 308, 2001
1HJF
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ALTERATION OF THE CO-SUBSTRATE SELECTIVITY OF DEACETOXYCEPHALOSPORIN C SYNTHASE: THE ROLE OF ARGININE-258
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXO-4-METHYLPENTANOIC ACID
Authors:Lee, H.J., Lloyd, M.D., Clifton, I.J., Harlos, K., Dubus, A., Baldwin, J.E., Frere, J.M., Schofield, C.J.
Deposit date:2001-01-15
Release date:2001-06-01
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1HJG
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ALTERATION OF THE CO-SUBSTRATE SELECTIVITY OF DEACETOXYCEPHALOSPORIN C SYNTHASE: THE ROLE OF ARGININE-258
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 3-METHYL-2-OXOBUTANOIC ACID
Authors:Lee, H.J., Lloyd, M.D., Clifton, I.J., Harlos, K., Dubus, A., Baldwin, J.E., Frere, J.M., Schofield, C.J.
Deposit date:2001-01-15
Release date:2001-06-01
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1CVW
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CRYSTAL STRUCTURE OF ACTIVE SITE-INHIBITED HUMAN COAGULATION FACTOR VIIA (DES-GLA)
Descriptor:COAGULATION FACTOR VIIA (LIGHT CHAIN) (DES-GLA), COAGULATION FACTOR VIIA (HEAVY CHAIN) (DES-GLA), N-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl}-L-alpha-glutamyl-N-[(2S,3S)-6-carbamimidamido-1-chloro-2-hydroxyhexan-3-yl]glycinamide, ...
Authors:Kemball-Cook, G., Johnson, D.J.D., Tuddenham, E.G.D., Harlos, K.
Deposit date:1999-08-24
Release date:1999-08-31
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla).
J.Struct.Biol., 127, 1999
1GVG
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CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE WITH NITRIC OXIDE
Descriptor:CLAVAMINATE SYNTHASE 1, FE (III) ION, 2-OXOGLUTARIC ACID, ...
Authors:Zhang, Z.H., Ren, J., McKinnon, C.H., Clifton, I.J., Harlos, K., Schofield, C.J.
Deposit date:2002-02-12
Release date:2003-02-07
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal Structure of a Clavaminate Synthase-Fe(II) -2-Oxoglutarate-Substrate-No Complex: Evidence for Metal Centered Rearrangements
FEBS Lett., 517, 2002
1HNF
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION
Descriptor:CD2, N-ACETYL-D-GLUCOSAMINE, SODIUM ION
Authors:Bodian, D.L., Jones, E.Y., Harlos, K., Stuart, D.I., Davis, S.J.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure, 2, 1994
1HNG
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CRYSTAL STRUCTURE AT 2.8 ANGSTROMS RESOLUTION OF A SOLUBLE FORM OF THE CELL ADHESION MOLECULE CD2
Descriptor:CD2
Authors:Jones, E.Y., Davis, S.J., Williams, A.F., Harlos, K., Stuart, D.I.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.
Nature, 360, 1992
1VCA
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CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION
Descriptor:HUMAN VASCULAR CELL ADHESION MOLECULE-1
Authors:Jones, E.Y., Harlos, K., Bottomley, M.J., Robinson, R.C., Driscoll, P.C., Edwards, R.M., Clements, J.M., Dudgeon, T.J., Stuart, D.I.
Deposit date:1995-03-21
Release date:1995-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
Nature, 373, 1995
5E8C
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PSEUDORABIES VIRUS NUCLEAR EGRESS COMPLEX, PUL31, PUL34
Descriptor:UL31, UL34 protein, ZINC ION, ...
Authors:Zeev-Ben-Mordehai, T., Cheleski, J., Whittle, C., El Omari, K., Harlos, K., Hagen, C., Klupp, B., Mettenleiter, T.C., Gruenewald, K.
Deposit date:2015-10-14
Release date:2015-12-23
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling.
Cell Rep, 13, 2015
1H15
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X-RAY CRYSTAL STRUCTURE OF HLA-DRA1*0101/DRB5*0101 COMPLEXED WITH A PEPTIDE FROM EPSTEIN BARR VIRUS DNA POLYMERASE
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DR BETA 1 CHAIN, ...
Authors:Lang, H., Jacobsen, H., Ikemizu, S., Andersson, C., Harlos, K., Madsen, L., Hjorth, P., Sondergaard, L., Svejgaard, A., Wucherpfennig, K., Stuart, D.I., Bell, J.I., Jones, E.Y., Fugger, L.
Deposit date:2002-07-02
Release date:2002-10-03
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3, 2002
2V2W
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T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Lee, J.K., Stewart-Jones, G., Dong, T., Harlos, K., Di Gleria, K., Dorrell, L., Douek, D.C., Van Der Merwe, P.A., Jones, E.Y., Mcmichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2V2X
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T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT.
Descriptor:HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, BETA-2 MICROGLOBULIN, ...
Authors:Lee, J.K., Stewart-Jones, G., Dong, T., harlos, K., Di Gleria, K., Dorrell, L., Douek, D.C., van der Merwe, P.A., Jones, E.Y., McMichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2VD8
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THE CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM BACILLUS ANTHRACIS (BA0252)
Descriptor:ALANINE RACEMASE, PYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, ...
Authors:Au, K., Ren, J., Walter, T.S., Harlos, K., Nettleship, J.E., Owens, R.J., Stuart, D.I., Esnouf, R.M., Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE)
Deposit date:2007-10-01
Release date:2008-05-20
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
2VD9
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THE CRYSTAL STRUCTURE OF ALANINE RACEMASE FROM BACILLUS ANTHRACIS (BA0252) WITH BOUND L-ALA-P
Descriptor:ALANINE RACEMASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Au, K., Ren, J., Walter, T.S., Harlos, K., Nettleship, J.E., Owens, R.J., Stuart, D.I., Esnouf, R.M., Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE)
Deposit date:2007-10-01
Release date:2008-05-20
Last modified:2012-02-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
2WBJ
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TCR COMPLEX
Descriptor:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, DRB1-15 BETA CHAIN, ...
Authors:Harkiolaki, M., Holmes, S.L., Svendsen, P., Gregersen, J.W., Jensen, L.T., McMahon, R., Friese, M.A., van Boxel, G., Etzensperger, R., Tzartos, J.S., Kranc, K., Sainsbury, S., Harlos, K., Mellins, E.D., Palace, J., Esiri, M.M., van der Merwe, P.A., Jones, E.Y., Fugger, L.
Deposit date:2009-03-02
Release date:2009-04-07
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:T Cell-Mediated Autoimmune Disease due to Low-Affinity Crossreactivity to Common Microbial Peptides.
Immunity, 30, 2009
2YQ2
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STRUCTURE OF BVDV1 ENVELOPE GLYCOPROTEIN E2, PH8
Descriptor:BVDV1 E2, N-ACETYL-D-GLUCOSAMINE
Authors:El Omari, K., Iourin, O., Harlos, K., Grimes, J.M., Stuart, D.I.
Deposit date:2012-11-04
Release date:2013-01-16
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies its Role in Cell Entry.
Cell Rep., 3, 2013
2YQ3
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STRUCTURE OF BVDV1 ENVELOPE GLYCOPROTEIN E2, PH5
Descriptor:BVDV1 E2, N-ACETYL-D-GLUCOSAMINE
Authors:El Omari, K., Iourin, O., Harlos, K., Grimes, J.M., Stuart, D.I.
Deposit date:2012-11-04
Release date:2013-01-16
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structure of a Pestivirus Envelope Glycoprotein E2 Clarifies its Role in Cell Entry.
Cell Rep., 3, 2013
4ZEL
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HUMAN DOPAMINE BETA-HYDROXYLASE
Descriptor:Dopamine beta-hydroxylase, COPPER (II) ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Vendelboe, T.V., Harris, P., Christensen, H.E.M., Harlos, K., Walter, T., Zhao, Y., Omari, K.
Deposit date:2015-04-20
Release date:2016-04-20
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of human dopamine beta-hydroxylase at 2.9 angstrom resolution.
Sci Adv, 2, 2016
6QGI
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CRYSTAL STRUCTURE OF VP5 FROM HALOARCHAEAL PLEOMORPHIC VIRUS 2
Descriptor:VP5, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION
Authors:El Omari, K., Walter, T.S., Harlos, K., Grimes, J.M., Stuart, D.I., Roine, E.
Deposit date:2019-01-11
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Nat Commun, 10, 2019
6QGL
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CRYSTAL STRUCTURE OF VP5 FROM HALOARCHAEAL PLEOMORPHIC VIRUS 6
Descriptor:VP5, BROMIDE ION
Authors:El Omari, K., Walter, T.S., Harlos, K., Grimes, J.M., Stuart, D.I., Roine, E.
Deposit date:2019-01-11
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins.
Nat Commun, 10, 2019
4AE2
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CRYSTAL STRUCTURE OF HUMAN FIBRILLAR PROCOLLAGEN TYPE III C- PROPEPTIDE TRIMER
Descriptor:COLLAGEN ALPHA-1(III) CHAIN, CALCIUM ION, NITRATE ION
Authors:Bourhis, J.M., Mariano, N., Zhao, Y., Harlos, K., Jones, E.Y., Moali, C., Aghajari, N., Hulmes, D.J.
Deposit date:2012-01-05
Release date:2012-09-12
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural Basis of Fibrillar Collagen Trimerization and Related Genetic Disorders.
Nat.Struct.Mol.Biol., 19, 2012
4AEJ
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CRYSTAL STRUCTURE OF HUMAN FIBRILLAR PROCOLLAGEN TYPE III C- PROPEPTIDE TRIMER
Descriptor:COLLAGEN ALPHA-1(III) CHAIN, CALCIUM ION, GLYCEROL
Authors:Bourhis, J.M., Mariano, N., Zhao, Y., Harlos, K., Jones, E.Y., Moali, C., Aghajari, N., Hulmes, D.J.S.
Deposit date:2012-01-11
Release date:2012-09-12
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural Basis of Fibrillar Collagen Trimerization and Related Genetic Disorders.
Nat.Struct.Mol.Biol., 19, 2012