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1D8J
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SOLUTION STRUCTURE OF THE CENTRAL CORE DOMAIN OF TFIIE BETA
Descriptor:GENERAL TRANSCRIPTION FACTOR TFIIE-BETA
Authors:Okuda, M., Watanabe, Y., Okamura, H., Hanaoka, F., Ohkuma, Y., Nishimura, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-10-25
Release date:2000-04-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface.
EMBO J., 19, 2000
1D8K
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SOLUTION STRUCTURE OF THE CENTRAL CORE DOMAIN OF TFIIE BETA
Descriptor:GENERAL TRANSCRIPTION FACTOR TFIIE-BETA
Authors:Okuda, M., Watanabe, Y., Okamura, H., Hanaoka, F., Ohkuma, Y., Nishimura, Y., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-10-25
Release date:2000-04-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the central core domain of TFIIEbeta with a novel double-stranded DNA-binding surface.
EMBO J., 19, 2000
1UB4
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CRYSTAL STRUCTURE OF MAZEF COMPLEX
Descriptor:MazF protein, MazE protein
Authors:Kamada, K., Hanaoka, F., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-03-28
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the MazE/MazF Complex. Molecular Bases of Antidote-Toxin Recognition
Mol.Cell, 11, 2003
1V33
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CRYSTAL STRUCTURE OF DNA PRIMASE FROM PYROCOCCUS HORIKOSHII
Descriptor:DNA primase small subunit, ZINC ION, PHOSPHATE ION
Authors:Ito, N., Nureki, O., Shirouzu, M., Yokoyama, S., Hanaoka, F., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-10-25
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis.
Genes Cells, 8, 2003
1V34
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CRYSTAL STRUCTURE OF PYROCOCCUS HORIKOSHII DNA PRIMASE-UTP COMPLEX
Descriptor:DNA primase small subunit, ZINC ION, URIDINE 5'-TRIPHOSPHATE
Authors:Ito, N., Nureki, O., Shirouzu, M., Yokoyama, S., Hanaoka, F., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-10-25
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis.
Genes Cells, 8, 2003
1VD4
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SOLUTION STRUCTURE OF THE ZINC FINGER DOMAIN OF TFIIE ALPHA
Descriptor:Transcription initiation factor IIE, alpha subunit, ZINC ION
Authors:Okuda, M., Tanaka, A., Arai, Y., Satoh, M., Okamura, H., Nagadoi, A., Hanaoka, F., Ohkuma, Y., Nishimura, Y.
Deposit date:2004-03-18
Release date:2004-10-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.
J.Biol.Chem., 279, 2004
1WYW
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CRYSTAL STRUCTURE OF SUMO1-CONJUGATED THYMINE DNA GLYCOSYLASE
Descriptor:G/T mismatch-specific thymine DNA glycosylase, Ubiquitin-like protein SMT3C, CHLORIDE ION, ...
Authors:Baba, D., Maita, N., Jee, J.G., Uchimura, Y., Saitoh, H., Sugasawa, K., Hanaoka, F., Tochio, H., Hiroaki, H., Shirakawa, M.
Deposit date:2005-02-17
Release date:2005-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of thymine DNA glycosylase conjugated to SUMO-1.
Nature, 435, 2005
2A6Q
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CRYSTAL STRUCTURE OF YEFM-YOEB COMPLEX
Descriptor:Antitoxin yefM, Toxin yoeB
Authors:Kamada, K., Hanaoka, F.
Deposit date:2005-07-04
Release date:2005-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Conformational Change in the Catalytic Site of the Ribonuclease YoeB Toxin by YefM Antitoxin
Mol.Cell, 19, 2005
2A6R
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CRYSTAL STRUCTURE OF YOEB UNDER PEG CONDITION
Descriptor:Toxin yoeB, MAGNESIUM ION
Authors:Kamada, K., Hanaoka, F.
Deposit date:2005-07-04
Release date:2005-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Conformational Change in the Catalytic Site of the Ribonuclease YoeB Toxin by YefM Antitoxin
Mol.Cell, 19, 2005
2A6S
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CRYSTAL STRUCTURE OF YOEB UNDER ISOPROPANOL CONDITION
Descriptor:Toxin yoeB, ISOPROPYL ALCOHOL
Authors:Kamada, K., Hanaoka, F.
Deposit date:2005-07-04
Release date:2005-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Conformational Change in the Catalytic Site of the Ribonuclease YoeB Toxin by YefM Antitoxin
Mol.Cell, 19, 2005
2D07
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CRYSTAL STRUCTURE OF SUMO-3-MODIFIED THYMINE-DNA GLYCOSYLASE
Descriptor:G/T mismatch-specific thymine DNA glycosylase, Ubiquitin-like protein SMT3B
Authors:Baba, D., Maita, N., Jee, J.G., Uchimura, Y., Saitoh, H., Sugasawa, K., Hanaoka, F., Tochio, H., Hiroaki, H., Shirakawa, M.
Deposit date:2005-07-26
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of SUMO-3-modified Thymine-DNA Glycosylase
J.Mol.Biol., 359, 2006
2E9X
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THE CRYSTAL STRUCTURE OF HUMAN GINS CORE COMPLEX
Descriptor:DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ...
Authors:Kamada, K., Hanaoka, F.
Deposit date:2007-01-27
Release date:2007-04-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the human GINS complex and its assembly and functional interface in replication initiation
Nat.Struct.Mol.Biol., 14, 2007
2RQQ
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STRUCTURE OF C-TERMINAL REGION OF CDT1
Descriptor:DNA replication factor Cdt1
Authors:Jee, J.G., Mizuno, T., Kamada, K., Tochio, H., Hiroaki, H., Hanaoka, F., Shirakawa, M.
Deposit date:2009-10-14
Release date:2010-03-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins
J.Biol.Chem., 285, 2010
3SI8
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HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX WITH THE 5'T OF A CPD IN THE ACTIVE SITE (TT2)
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*A*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Biertumpfel, C., Zhao, Y., Kondo, Y., Ramon-Maiques, S., Gregory, M., Lee, J.Y., Masutani, C., Lehmann, A.R., Hanaoka, F., Yang, W.
Deposit date:2011-06-17
Release date:2011-08-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
4DL2
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE CG TEMPLATE (GG0A)
Descriptor:DNA polymerase eta, DNA (5'-D(*AP*CP*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*G)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL3
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE GG TEMPLATE (GG0B).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*C)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL4
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE THE 3'G OF CISPLATIN CROSSLINKED GS (PT-GG1).
Descriptor:DNA polymerase eta, DNA (5'-D(P*GP*GP*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*AP*G)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y.-J., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL5
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HUMAN DNA POLYMERASE ETA INSERTING DCMPNPP OPPOSITE THE 5'G OF CISPLATIN CROSSLINKED GS (PT-GG2).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(P*TP*AP*GP*TP*GP*TP*GP*AP*C)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hanaoka, F., Hua, Y., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2014-10-08
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL6
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HUMAN DNA POLYMERASE ETA EXTENDING PRIMER IMMEDIATELY AFTER CISPLATIN CROSSLINK (PT-GG3).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*TP*CP*GP*GP*CP*AP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*TP*GP*CP*C)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4DL7
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HUMAN DNA POLYMERASE ETA FAILS TO EXTEND PRIMER 2 NUCLEOTIDE AFTER CISPLATIN CROSSLINK (PT-GG4).
Descriptor:DNA polymerase eta, DNA (5'-D(*TP*AP*CP*TP*CP*GP*GP*TP*CP*AP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*TP*GP*AP*CP*CP*G)-3'), ...
Authors:Zhao, Y., Biertumpfel, C., Gregory, M., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2012-02-05
Release date:2012-05-09
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta
Proc.Natl.Acad.Sci.USA, 109, 2012
4J9K
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A T AT THE PRIMER 3' END (TA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9L
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A C AT THE PRIMER 3' END (CA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9M
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER AN A AT THE PRIMER 3' END (AA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9N
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: MISINCORPORATION G OPPOSITE T AFTER A G AT THE PRIMER 3' END (GA/G)
Descriptor:DNA polymerase eta, DNA, MAGNESIUM ION, ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (1.956 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J9O
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: PRIMER EXTENSION AFTER A T:G MISPAIR
Descriptor:DNA polymerase eta, DNA (5'-D(*T*AP*CP*TP*TP*AP*TP*GP*AP*CP*GP*T)-3'), DNA (5'-D(*T*AP*CP*GP*TP*CP*AP*TP*G)-3'), ...
Authors:Zhao, Y., Gregory, M., Biertumpfel, C., Hua, Y., Hanaoka, F., Yang, W.
Deposit date:2013-02-16
Release date:2013-05-01
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.
Proc.Natl.Acad.Sci.USA, 110, 2013
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