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5MJE
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BU of 5mje by Molmil
Crystal structure of the HigB2 toxin in complex with Nb8
Descriptor: Cytotoxic translational repressor of toxin-antitoxin stability system, DI(HYDROXYETHYL)ETHER, Nanobody 8, ...
Authors:Hadzi, S, Loris, R.
Deposit date:2016-11-30
Release date:2017-04-05
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.599 Å)
Cite:Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
8A0W
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BU of 8a0w by Molmil
Crystal structure of the HigA2 antitoxin in complex with operator DNA
Descriptor: Antitoxin HigA-2, DNA (17-MER), PHOSPHATE ION
Authors:Hadzi, S, Loris, R.
Deposit date:2022-05-30
Release date:2023-05-03
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.334 Å)
Cite:Fuzzy recognition by the prokaryotic transcription factor HigA2 from Vibrio cholerae.
Nat Commun, 15, 2024
5J9I
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BU of 5j9i by Molmil
Crystal structure of the HigA2 antitoxin C-terminal domain
Descriptor: Antitoxin igA-2
Authors:Hadzi, S, Loris, R.
Deposit date:2016-04-10
Release date:2017-04-05
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
5JA9
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BU of 5ja9 by Molmil
Crystal structure of the HigB2 toxin in complex with Nb6
Descriptor: 1,2-ETHANEDIOL, Nanobody 6, SULFATE ION, ...
Authors:Hadzi, S, Loris, R.
Deposit date:2016-04-12
Release date:2017-04-05
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
5JAA
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BU of 5jaa by Molmil
Crystal structure of the HigBA2 toxin-antitoxin complex
Descriptor: Antitoxin igA-2, Toxin HigB-2
Authors:Hadzi, S, Loris, R.
Deposit date:2016-04-12
Release date:2017-04-05
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (2.993 Å)
Cite:Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
5JA8
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BU of 5ja8 by Molmil
Crystal structure of the HigB2 toxin in complex with Nb2
Descriptor: 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Hadzi, S, Loris, R.
Deposit date:2016-04-12
Release date:2017-04-05
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Ribosome-dependent Vibrio cholerae mRNAse HigB2 is regulated by a beta-strand sliding mechanism.
Nucleic Acids Res., 45, 2017
8A0X
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BU of 8a0x by Molmil
Crystal structure of the HigB2-HigA2 tetramer in complex with operator DNA
Descriptor: Antitoxin HigA-2, DNA (30-MER), DNA (31-MER), ...
Authors:Hadzi, S, Loris, R.
Deposit date:2022-05-30
Release date:2023-05-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:Fuzzy DNA recognition by a prokaryotic transcription factor
To Be Published
7A4Y
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BU of 7a4y by Molmil
Crystal structure of the P5P6 coiled-coil in complex with nanobody Nb34.
Descriptor: 1,2-ETHANEDIOL, Coiled-coil P5 peptide, Coiled-coil P6 peptide, ...
Authors:Hadzi, S.
Deposit date:2020-08-20
Release date:2021-05-05
Method:X-RAY DIFFRACTION (2.157 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A4T
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BU of 7a4t by Molmil
Crystal structure of the GCN coiled-coil in complex with nanobody Nb39
Descriptor: 1,2-ETHANEDIOL, ACETYL GROUP, GCN4 isoform 1, ...
Authors:Hadzi, S.
Deposit date:2020-08-20
Release date:2021-05-05
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (2.124 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A50
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BU of 7a50 by Molmil
Crystal structure of the APH coiled-coil in complex with nanobody Nb26
Descriptor: 1,2-ETHANEDIOL, Coiled-coil APH, Nanobody Nb26
Authors:Hadzi, S.
Deposit date:2020-08-20
Release date:2021-05-05
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A48
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BU of 7a48 by Molmil
Crystal structure of the APH coiled-coil in complex with Nb49
Descriptor: APH colied-coil, Nanobody 49
Authors:Hadzi, S.
Deposit date:2020-08-19
Release date:2021-05-05
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (1.547 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7A4D
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BU of 7a4d by Molmil
Crystal structure of the APH coiled-coil in complex with nanobodies Nb28 and Nb30
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, APH coiled-coil, ...
Authors:Hadzi, S.
Deposit date:2020-08-19
Release date:2021-05-05
Last modified:2021-08-11
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures.
Proc.Natl.Acad.Sci.USA, 118, 2021
7OWX
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BU of 7owx by Molmil
Structure of coiled-coil tetramer from SARS-CoV-2 spike stalk region
Descriptor: 1,2-ETHANEDIOL, Spike protein S2, ZINC ION
Authors:Zivic, Z, Hadzi, S.
Deposit date:2021-06-21
Release date:2022-03-16
Method:X-RAY DIFFRACTION (1.929 Å)
Cite:Structural polymorphism of coiled-coils from the stalk domain of SARS-CoV-2 spike protein.
Faseb J., 36, 2022
8P4Y
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BU of 8p4y by Molmil
Coiled-coil protein origami triangle
Descriptor: GLYCEROL, Protein origami triangle
Authors:Satler, T, Hadzi, S, Jerala, R.
Deposit date:2023-05-23
Release date:2023-08-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Crystal Structure of de Novo Designed Coiled-Coil Protein Origami Triangle.
J.Am.Chem.Soc., 145, 2023
8BT1
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BU of 8bt1 by Molmil
YdaT transcription regulator (CII functional analog)
Descriptor: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
Authors:Prolic-Kalinsek, M, Loris, R.
Deposit date:2022-11-27
Release date:2023-02-22
Last modified:2023-03-22
Method:X-RAY DIFFRACTION (2.39788437 Å)
Cite:Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7.
Acta Crystallogr D Struct Biol, 79, 2023
6F8S
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BU of 6f8s by Molmil
Toxin-Antitoxin complex GraTA
Descriptor: DI(HYDROXYETHYL)ETHER, Putative Killer protein, SULFATE ION, ...
Authors:Talavera, A, Loris, R.
Deposit date:2017-12-13
Release date:2018-07-11
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
6F8H
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BU of 6f8h by Molmil
antitoxin GraA
Descriptor: XRE family transcriptional regulator
Authors:Talavera, A, Loris, R.
Deposit date:2017-12-13
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
6FIX
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BU of 6fix by Molmil
antitoxin GraA in complex with its operator
Descriptor: DNA (30-MER), XRE family transcriptional regulator
Authors:Talavera, A, Loris, R.
Deposit date:2018-01-19
Release date:2019-01-30
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
8C7K
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BU of 8c7k by Molmil
YdaS from E. coli O157:H7 cryptic prophage CP-933P
Descriptor: Phage antirepressor protein Cro
Authors:Prolic-Kalinsek, M, Volkov, A.N, Loris, R.
Deposit date:2023-01-16
Release date:2023-01-25
Last modified:2023-03-22
Method:SOLUTION NMR
Cite:Structural basis of DNA binding by YdaT, a functional equivalent of the CII repressor in the cryptic prophage CP-933P from Escherichia coli O157:H7.
Acta Crystallogr D Struct Biol, 79, 2023
8CO2
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BU of 8co2 by Molmil
YdaS N-terminal domain from prophage CP-933P in E. coli O157:H7
Descriptor: ISOPROPYL ALCOHOL, Putative antirepressor protein Cro, SULFATE ION
Authors:Prolic-Kalinsek, M, Loris, R.
Deposit date:2023-02-26
Release date:2023-03-08
Method:X-RAY DIFFRACTION (1.63880718 Å)
Cite:YdaS from the Escherichia coli cryptic prophage CP-933P forms an evolutionary link between Cro repressors and HigA antitoxins
To Be Published

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PDB entries from 2024-04-24

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