Author results

1L6P
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N-TERMINAL OF DSBD (RESIDUES 20-144) FROM E. COLI.
Descriptor:Thiol:disulfide interchange protein dsbD
Authors:Goulding, C.W., Sawaya, M.R., Parseghian, A.
Deposit date:2002-03-12
Release date:2002-06-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Thiol-disulfide exchange in an immunoglobulin-like fold: structure of the N-terminal domain of DsbD.
Biochemistry, 41, 2002
1LMI
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1.5 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS-MPT63
Descriptor:Immunogenic protein MPT63/MPB63
Authors:Goulding, C.W., Parseghian, A., Sawaya, M.R., Cascio, D., Apostol, M., Gennaro, M.L., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-01
Release date:2002-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution
Protein Sci., 11, 2002
1LU4
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1.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS DISULFIDE OXIDOREDUCTASE HOMOLOGOUS TO E. COLI DSBE: IMPLICATIONS FOR FUNCTIONS
Descriptor:SOLUBLE SECRETED ANTIGEN MPT53
Authors:Goulding, C.W., Apostol, M.I., Gleiter, S., Parseghian, A., Bardwell, J., Gennaro, M., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-05-21
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Gram-positive DsbE Proteins Function Differently from Gram-negative DsbE Homologs: A STRUCTURE TO FUNCTION ANALYSIS OF DsbE FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 279, 2004
1NBU
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7,8-DIHYDRONEOPTERIN ALDOLASE COMPLEXED WITH PRODUCT FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Probable dihydroneopterin aldolase, 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE
Authors:Goulding, C.W., Apostol, M.I., Sawaya, M.R., Phillips, M., Parseghian, A., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2002-12-03
Release date:2004-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
1U5H
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STRUCTURE OF CITRATE LYASE BETA SUBUNIT FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:citE, FORMIC ACID
Authors:Goulding, C.W., Lekin, T., Kim, C.Y., Segelke, B., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-07-27
Release date:2004-10-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J.Mol.Biol., 365, 2007
1U5V
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STRUCTURE OF CITE COMPLEXED WITH TRIPHOSPHATE GROUP OF ATP FORM MYCOBACTERIUM TUBERCULOSIS
Descriptor:citE, ADENOSINE-5'-TRIPHOSPHATE, FORMIC ACID
Authors:Goulding, C.W., Lerkin, T., Kim, C.Y., Segelke, B., Terwilliger, T., Eisenberg, E., TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-07-28
Release date:2004-10-12
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of Mycobacterium tuberculosis citrate lyase beta subunit and its unusual triphosphate binding site
To be Published
1Z6K
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CITRATE LYASE BETA SUBUNIT COMPLEXED WITH OXALOACETATE AND MAGNESIUM FROM M. TUBERCULOSIS
Descriptor:Citrate Lyase beta subunit, OXALOACETATE ION, MAGNESIUM ION
Authors:Goulding, C.W., Bowers, P.M., Segelke, B., Lekin, T., Kim, C.Y., Terwilliger, T.C., Eisenberg, D., TB Structural Genomics Consortium (TBSGC)
Deposit date:2005-03-22
Release date:2005-05-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J.Mol.Biol., 365, 2007
1Z9W
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TETRAMERIC STRUCTURE OF APO-7,8-DIHYDRONEOPTERIN ALDOLASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Dihydroneopterin aldolase
Authors:Goulding, C.W., Apostol, M.I., Sawaya, M.R., Philips, M., Parseghian, A., Eisenberg, D., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Deposit date:2005-04-05
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
3MAY
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CRYSTAL STRUCTURE OF A SECRETED MYCOBACTERIUM TUBERCULOSIS HEME-BINDING PROTEIN
Descriptor:POSSIBLE EXPORTED PROTEIN
Authors:Goulding, C.W., Chim, N.
Deposit date:2010-03-24
Release date:2011-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Discovery and characterization of a unique mycobacterial heme acquisition system.
Proc.Natl.Acad.Sci.USA, 108, 2011
5J4A
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CDIA-CT TOXIN FROM BURKHOLDERIA PSEUDOMALLEI E479 IN COMPLEX WITH COGNATE CDII IMMUNITY PROTEIN
Descriptor:tRNA nuclease CdiA, Immunity protein CdiI
Authors:Goulding, C.W., Johnson, P.M.
Deposit date:2016-03-31
Release date:2016-07-27
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Functional Diversity of Cytotoxic tRNase/Immunity Protein Complexes from Burkholderia pseudomallei.
J.Biol.Chem., 291, 2016
5J5V
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CDIA-CT FROM UROPATHOGENIC ESCHERICHIA COLI IN COMPLEX WITH COGNATE IMMUNITY PROTEIN AND CYSK
Descriptor:Cysteine synthase A, tRNA nuclease CdiA, Immunity protein CdiI
Authors:Goulding, C.W., Johnson, P.M., Morse, R.P.
Deposit date:2016-04-04
Release date:2016-07-27
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Unraveling the essential role of CysK in CDI toxin activation.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
3UNO
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MYCOBACTERIUM TUBERCULOSIS FERRITIN HOMOLOG, BFRB
Descriptor:Probable bacterioferritin BfrB
Authors:McMath, L.M., Contreras, H., Goulding, C.W., TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-11-16
Release date:2012-11-21
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Mycobacterium tuberculosis ferritin homolog, BfrB
To be Published
6CP8
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CONTACT-DEPENDENT GROWTH INHIBITION TOXIN-IMMUNITY PROTEIN COMPLEX FROM FROM E. COLI 3006
Descriptor:CdiA, CdiI, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2018-03-13
Release date:2019-03-13
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
6CP9
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CONTACT-DEPENDENT GROWTH INHIBITION TOXIN - IMMUNITY PROTEIN COMPLEX FROM KLEBSIELLA PNEUMONIAE 342
Descriptor:CdiA, CdiI
Authors:Michalska, K., Stols, L., Eschenfeldt, W., Hayes, C.S., Goulding, C.W., Joachimiak, A., Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI)
Deposit date:2018-03-13
Release date:2019-03-13
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
3HX9
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STRUCTURE OF HEME-DEGRADER, MHUD (RV3592), FROM MYCOBACTERIUM TUBERCULOSIS WITH TWO HEMES BOUND IN ITS ACTIVE SITE
Descriptor:Protein Rv3592, PROTOPORPHYRIN IX CONTAINING FE, CHLORIDE ION
Authors:Chim, N., Nguyen, T.Q., Iniguez, A., Goulding, C.W.
Deposit date:2009-06-19
Release date:2009-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Unusual Diheme Conformation of the Heme-Degrading Protein from Mycobacterium tuberculosis
J.Mol.Biol., 395, 2009
3IOS
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STRUCTURE OF MTB DSBF IN ITS MIXED OXIDIZED AND REDUCED FORMS
Descriptor:Disulfide bond forming protein (DsbF)
Authors:Chim, N., Goulding, C.W.
Deposit date:2009-08-14
Release date:2010-01-05
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis.
J.Mol.Biol., 396, 2010
3OJ5
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MYCOBACTERIUM TUBERCULOSIS FERRITIN HOMOLOG, BFRB
Descriptor:Ferritin family protein
Authors:McMath, L.M., Goulding, C.W.
Deposit date:2010-08-20
Release date:2011-09-07
Method:X-RAY DIFFRACTION (2.845 Å)
Cite:Mycobacterium tuberculosis ferritin homolog, BfrB
To be Published
3QB9
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MYCOBACTERIUM TUBERCULOSIS BACTERIOFERRITIN, BFRA
Descriptor:Bacterioferritin, FE (III) ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:McMath, L.M., Goulding, C.W., TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-01-12
Release date:2012-02-08
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Mycobacterium tuberculosis bacterioferritin, BfrA
To be Published
3QLI
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CRYSTAL STRUCTURE OF RIPA FROM YERSINIA PESTIS
Descriptor:Coenzyme A transferase, ACETATE ION
Authors:Torres, R., Goulding, C.W.
Deposit date:2011-02-02
Release date:2012-01-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis.
Plos One, 6, 2011
3QLK
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CRYSTAL STRUCTURE OF RIPA FROM YERSINIA PESTIS
Descriptor:Coenzyme A transferase
Authors:Torres, R., Goulding, C.W.
Deposit date:2011-02-02
Release date:2012-01-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis.
Plos One, 6, 2011
3QLL
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CRYSTAL STRUCTURE OF RIPC FROM YERSINIA PESTIS
Descriptor:Citrate lyase
Authors:Torres, R., Goulding, C.W.
Deposit date:2011-02-02
Release date:2012-01-11
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural insights into RipC, a putative citrate lyase beta subunit from a Yersinia pestis virulence operon
Acta Crystallogr.,Sect.F, 68, 2012
3S8D
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CRYSTAL STRUCTURE OF RIPA FROM YERSINIA PESTIS
Descriptor:Coenzyme A transferase
Authors:Torres, R., Goulding, C.W.
Deposit date:2011-05-27
Release date:2012-01-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis.
Plos One, 6, 2011
3SIK
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CRYSTAL STRUCTURE OF THE BACILLUS ANTHRACIS HEMOPHORE ISDX1 COMPLEXED WITH HEME
Descriptor:Conserved domain protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Owens, C.P., Goulding, C.W.
Deposit date:2011-06-19
Release date:2012-05-02
Method:X-RAY DIFFRACTION (2.149 Å)
Cite:Differential function of lip residues in the mechanism and biology of an anthrax hemophore.
Plos Pathog., 8, 2012
3UOF
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MYCOBACTERIUM TUBERCULOSIS BACTERIOFERRITIN, BFRA
Descriptor:Bacterioferritin, FE (III) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:McMath, L.M., Goulding, C.W., TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-11-16
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:Mycobacterium tuberculosis bacterioferritin, BfrA
To be Published
3UOI
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MYCOBACTERIUM TUBERCULOSIS BACTERIOFERRITIN, BFRA
Descriptor:Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE
Authors:McMath, L.M., Goulding, C.W., TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-11-16
Release date:2012-12-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mycobacterium tuberculosis bacterioferritin, BfrA
To be Published
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