Author results

1CCA
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THE ASP-HIS-FE TRIAD OF CYTOCHROME C PEROXIDASE CONTROLS THE REDUCTION POTENTIAL, ELECTRONIC STRUCTURE, AND COUPLING OF THE TRYPTOPHAN FREE-RADICAL TO THE HEME
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Goodin, D.B., Mcree, D.E.
Deposit date:1993-01-04
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Asp-His-Fe triad of cytochrome c peroxidase controls the reduction potential, electronic structure, and coupling of the tryptophan free radical to the heme.
Biochemistry, 32, 1993
1CCB
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THE ASP-HIS-FE TRIAD OF CYTOCHROME C PEROXIDASE CONTROLS THE REDUCTION POTENTIAL, ELECTRONIC STRUCTURE, AND COUPLING OF THE TRYPTOPHAN FREE-RADICAL TO THE HEME
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Goodin, D.B., Mcree, D.E.
Deposit date:1993-01-04
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Asp-His-Fe triad of cytochrome c peroxidase controls the reduction potential, electronic structure, and coupling of the tryptophan free radical to the heme.
Biochemistry, 32, 1993
1CCC
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THE ASP-HIS-FE TRIAD OF CYTOCHROME C PEROXIDASE CONTROLS THE REDUCTION POTENTIAL, ELECTRONIC STRUCTURE, AND COUPLING OF THE TRYPTOPHAN FREE-RADICAL TO THE HEME
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Goodin, D.B., Mcree, D.E.
Deposit date:1993-01-04
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Asp-His-Fe triad of cytochrome c peroxidase controls the reduction potential, electronic structure, and coupling of the tryptophan free radical to the heme.
Biochemistry, 32, 1993
1RYC
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CYTOCHROME C PEROXIDASE W191G FROM SACCHAROMYCES CEREVISIAE
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, BENZIMIDAZOLE
Authors:Fitzgerald, M.M., Musah, R., Mcree, D.E., Goodin, D.B.
Deposit date:1996-05-10
Release date:1996-11-08
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1AA4
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SPECIFICITY OF LIGAND BINDING IN A BURIED POLAR CAVITY OF CYTOCHROME C PEROXIDASE
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Musah, R.A., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-01-22
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1AC4
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VARIATION IN THE STRENGTH OF A CH TO O HYDROGEN BOND IN AN ARTIFICIAL PROTEIN CAVITY (2,3,4-TRIMETHYL-1,3-THIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2,3,4-TRIMETHYL-1,3-THIAZOLE
Authors:Musah, R.A., Jensen, G.M., Bunte, S.W., Rosenfeld, R., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-12
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Variation in strength of an unconventional C-H to O hydrogen bond in an engineered protein cavity
J.Am.Chem.Soc., 119, 1997
1AC8
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VARIATION IN THE STRENGTH OF A CH TO O HYDROGEN BOND IN AN ARTIFICIAL PROTEIN CAVITY (3,4,5-TRIMETHYLTHIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 3,4,5-TRIMETHYL-1,3-THIAZOLE
Authors:Musah, R.A., Jensen, G.M., Bunte, S.W., Rosenfeld, R., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-14
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Variation in strength of an unconventional C-H to O hydrogen bond in an engineered protein cavity
J.Am.Chem.Soc., 119, 1997
1AEB
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (3-METHYLTHIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 3-METHYLTHIAZOLIUM ION
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-24
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AED
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (3,4-DIMETHYLTHIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 3,4-DIMETHYLTHIAZOLIUM ION
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-24
Release date:1997-09-04
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEE
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (ANILINE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, ANILINE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-24
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEF
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (3-AMINOPYRIDINE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 3-AMINOPYRIDINE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-24
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEG
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (4-AMINOPYRIDINE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 4-AMINOPYRIDINE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-24
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEH
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (2-AMINO-4-METHYLTHIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINO-4-METHYLTHIAZOLE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-24
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEJ
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (1-VINYLIMIDAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 1-VINYLIMIDAZOLE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEK
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (INDOLINE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, INDOLINE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEM
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (IMIDAZO[1,2-A]PYRIDINE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZO[1,2-A]PYRIDINE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEN
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (2-AMINO-5-METHYLTHIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINO-5-METHYLTHIAZOLE
Authors:Musah, R.A., Jensen, G.M., Bunte, S.W., Rosenfeld, R., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEO
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (2-AMINOPYRIDINE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINOPYRIDINE
Authors:Musah, R.A., Jensen, G.M., Bunte, S.W., Rosenfeld, R., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AEQ
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VARIATION IN THE STRENGTH OF A CH TO O HYDROGEN BOND IN AN ARTIFICIAL PROTEIN CAVITY (2-ETHYLIMIDAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-ETHYLIMIDAZOLE
Authors:Musah, R.A., Jensen, G.M., Bunte, S.W., Rosenfeld, R., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
J.Mol.Biol., 315, 2002
1AES
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SPECIFICITY OF LIGAND BINDING TO A BURIED POLAR CAVITY AT THE ACTIVE SITE OF CYTOCHROME C PEROXIDASE (IMIDAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, IMIDAZOLE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1AET
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VARIATION IN THE STRENGTH OF A CH TO O HYDROGEN BOND IN AN ARTIFICIAL PROTEIN CAVITY (1-METHYLIMIDAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 1-METHYLIMIDAZOLE
Authors:Musah, R.A., Jensen, G.M., Bunte, S.W., Rosenfeld, R., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1AEU
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SPECIFICITY OF LIGAND BINDING IN A POLAR CAVITY OF CYTOCHROME C PEROXIDASE (2-METHYLIMIDAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-METHYLIMIDAZOLE
Authors:Musah, R.A., Jensen, G.M., Fitzgerald, M.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1AEV
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INTRODUCTION OF NOVEL SUBSTRATE OXIDATION INTO CYTOCHROME C PEROXIDASE BY CAVITY COMPLEMENTATION: OXIDATION OF 2-AMINOTHIAZOLE AND COVALENT MODIFICATION OF THE ENZYME (2-AMINOTHIAZOLE)
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE, 2-AMINOTHIAZOLE
Authors:Musah, R.A., Fitzgerald, M.M., Jensen, G.M., Mcree, D.E., Goodin, D.B.
Deposit date:1997-02-25
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Introduction of novel substrate oxidation into cytochrome c peroxidase by cavity complementation: oxidation of 2-aminothiazole and covalent modification of the enzyme.
Biochemistry, 36, 1997
1CCI
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HOW FLEXIBLE ARE PROTEINS? TRAPPING OF A FLEXIBLE LOOP
Descriptor:CYTOCHROME C PEROXIDASE, 2,3-DIMETHYLIMIDAZOLIUM ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Musah, R.A., Wilcox, S.K., Goodin, D.B., Mcree, D.E.
Deposit date:1996-12-18
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity.
Nat.Struct.Biol., 3, 1996
1CCJ
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CONFORMER SELECTION BY LIGAND BINDING OBSERVED WITH PROTEIN CRYSTALLOGRAPHY
Descriptor:CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Cao, Y., Musah, R.A., Wilcox, S.K., Goodin, D.B., Mcree, D.E.
Deposit date:1997-01-22
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Protein conformer selection by ligand binding observed with crystallography.
Protein Sci., 7, 1998