Author results

1SOR
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AQUAPORIN-0 MEMBRANE JUNCTIONS REVEAL THE STRUCTURE OF A CLOSED WATER PORE
分子名称:Aquaporin-0
著者Gonen, T., Sliz, P., Kistler, J., Cheng, Y., Walz, T.
登録日2004-03-15
公開日2004-05-11
最終更新日2018-01-31
実験手法ELECTRON CRYSTALLOGRAPHY (3 Å)
主引用文献Aquaporin-0 membrane junctions reveal the structure of a closed water pore
Nature, 429, 2004
2B6O
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ELECTRON CRYSTALLOGRAPHIC STRUCTURE OF LENS AQUAPORIN-0 (AQP0) (LENS MIP) AT 1.9A RESOLUTION, IN A CLOSED PORE STATE
分子名称:Lens fiber major intrinsic protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE
著者Gonen, T., Cheng, Y., Sliz, P., Hiroaki, Y., Fujiyoshi, Y., Harrison, S.C., Walz, T.
登録日2005-10-03
公開日2005-12-06
最終更新日2018-07-18
実験手法ELECTRON CRYSTALLOGRAPHY (1.9 Å)
主引用文献Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
2B6P
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X-RAY STRUCTURE OF LENS AQUAPORIN-0 (AQP0) (LENS MIP) IN AN OPEN PORE STATE
分子名称:Lens fiber major intrinsic protein
著者Gonen, T., Cheng, Y., Sliz, P., Hiroaki, Y., Fujiyoshi, Y., Harrison, S.C., Walz, T.
登録日2005-10-03
公開日2005-12-06
最終更新日2011-10-26
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
6C9I
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SINGLE-PARTICLE RECONSTRUCTION OF DARP14 - A DESIGNED PROTEIN SCAFFOLD DISPLAYING ~17KDA DARPIN PROTEINS - SCAFFOLD
分子名称:DARP14 - Subunit A with DARPin, DARP14 - Subunit B
著者Gonen, S., Liu, Y., Yeates, T.O., Gonen, T.
登録日2018-01-26
公開日2018-03-21
最終更新日2018-04-11
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C9K
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SINGLE-PARTICLE RECONSTRUCTION OF DARP14 - A DESIGNED PROTEIN SCAFFOLD DISPLAYING ~17KDA DARPIN PROTEINS
分子名称:DARP14 - Subunit A with DARPin, DARP14 - Subunit B
著者Gonen, S., Liu, Y., Yeates, T.O., Gonen, T.
登録日2018-01-26
公開日2018-03-21
最終更新日2018-04-11
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Near-atomic cryo-EM imaging of a small protein displayed on a designed scaffolding system.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MXF
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MICROED STRUCTURE OF THIOSTREPTON AT 1.9 A RESOLUTION
分子名称:Thiostrepton
著者Jones, C.G., Martynowycz, M.W., Hattne, J., Fulton, T., Stoltz, B.M., Rodriguez, J.A., Nelson, H.M., Gonen, T.
登録日2018-10-30
公開日2018-11-21
最終更新日2019-02-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.91 Å)
主引用文献The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination.
ACS Cent Sci, 4, 2018
3J07
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MODEL OF A 24MER ALPHAB-CRYSTALLIN MULTIMER
分子名称:Alpha-crystallin B chain
著者Jehle, S., Vollmar, B., Bardiaux, B., Dove, K.K., Rajagopal, P., Gonen, T., Oschkinat, H., Klevit, R.E.
登録日2011-04-27
公開日2016-01-20
最終更新日2019-04-24
実験手法SOLID-STATE NMR (20 Å), SOLUTION SCATTERING, ELECTRON MICROSCOPY
主引用文献N-terminal domain of {alpha}B-crystallin provides a conformational switch for multimerization and structural heterogeneity.
Proc.Natl.Acad.Sci.USA, 108, 2011
3J41
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PSEUDO-ATOMIC MODEL OF THE AQUAPORIN-0/CALMODULIN COMPLEX DERIVED FROM ELECTRON MICROSCOPY
分子名称:Lens fiber major intrinsic protein, Calmodulin, CALCIUM ION
著者Reichow, S.L., Clemens, D.M., Freites, J.A., Nemeth-Cahalan, K.L., Heyden, M., Tobias, D.J., Hall, J.E., Gonen, T.
登録日2013-05-31
公開日2013-07-31
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.
Nat.Struct.Mol.Biol., 20, 2013
3J4G
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STRUCTURE OF LYSOZYME SOLVED BY MICROED TO 2.9 A
分子名称:Lysozyme C
著者Shi, D., Nannenga, B.L., Iadanza, M.G., Gonen, T.
登録日2013-08-12
公開日2013-11-13
最終更新日2015-04-15
実験手法ELECTRON CRYSTALLOGRAPHY (2.901 Å)
主引用文献Three-dimensional electron crystallography of protein microcrystals.
Elife, 2, 2013
3J4Q
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PSEUDO-ATOMIC MODEL OF THE AKAP18-PKA COMPLEX IN A BENT CONFORMATION DERIVED FROM ELECTRON MICROSCOPY
分子名称:A-kinase anchor protein 18, cAMP-dependent protein kinase type II-alpha regulatory subunit, cAMP-dependent protein kinase catalytic subunit alpha
著者Reichow, S.L., Gonen, T.
登録日2013-09-25
公開日2013-11-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.
Elife, 2, 2013
3J4R
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PSEUDO-ATOMIC MODEL OF THE AKAP18-PKA COMPLEX IN A LINEAR CONFORMATION DERIVED FROM ELECTRON MICROSCOPY
分子名称:A-kinase anchor protein 18, cAMP-dependent protein kinase type II-alpha regulatory subunit, cAMP-dependent protein kinase catalytic subunit alpha
著者Reichow, S.L., Gonen, T.
登録日2013-09-25
公開日2013-11-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (35 Å)
主引用文献Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.
Elife, 2, 2013
3J6K
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2.5A STRUCTURE OF LYSOZYME SOLVED BY MICROED
分子名称:Lysozyme C
著者Nannenga, B.L., Shi, D., Leslie, A.G.W., Gonen, T.
登録日2014-03-18
公開日2014-08-13
最終更新日2015-04-08
実験手法ELECTRON CRYSTALLOGRAPHY (2.496 Å)
主引用文献High-resolution structure determination by continuous-rotation data collection in MicroED.
Nat.Methods, 11, 2014
3J7B
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CATALASE SOLVED AT 3.2 ANGSTROM RESOLUTION BY MICROED
分子名称:Catalase, PROTOPORPHYRIN IX CONTAINING FE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Nannenga, B.L., Shi, D., Hattne, J., Reyes, F.E., Gonen, T.
登録日2014-06-09
公開日2014-10-08
最終更新日2015-04-08
実験手法ELECTRON CRYSTALLOGRAPHY (3.2 Å)
主引用文献Catalase solved at 3.2 Angstrom resolution by MicroED
eLife, 2014
4JR9
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CRYSTAL STRUCTURE OF NITRATE/NITRITE EXCHANGER NARK
分子名称:Nitrite extrusion protein 1, Immunoglobulin Gamma-2a, Heavy chain, ...
著者Zheng, H., Wisedchaisri, G., Gonen, T.
登録日2013-03-21
公開日2013-05-15
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a nitrate/nitrite exchanger.
Nature, 497, 2013
4JRE
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CRYSTAL STRUCTURE OF NITRATE/NITRITE EXCHANGER NARK WITH NITRITE BOUND
分子名称:Nitrite extrusion protein 1, Immunoglobulin Gamma-2a, Heavy chain, ...
著者Zheng, H., Wisedchaisri, G., Gonen, T.
登録日2013-03-21
公開日2013-05-15
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a nitrate/nitrite exchanger.
Nature, 497, 2013
4QIQ
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CRYSTAL STRUCTURE OF D-XYLOSE-PROTON SYMPORTER
分子名称:D-xylose-proton symporter, ZINC ION
著者Wisedchaisri, G., Park, M., Iadanza, M.G., Zheng, H., Gonen, T.
登録日2014-06-01
公開日2014-08-06
最終更新日2014-08-27
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE.
Nat Commun, 5, 2014
4RIL
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STRUCTURE OF THE AMYLOID FORMING SEGMENT, GAVVTGVTAVA, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 68-78, DETERMINED BY ELECTRON DIFFRACTION
分子名称:Alpha-synuclein
著者Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2018-04-25
実験手法ELECTRON CRYSTALLOGRAPHY (1.43 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4TQL
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COMPUTATIONALLY DESIGNED THREE HELIX BUNDLE
分子名称:Three helix bundle
著者Nannenga, B.L., Oberdorfer, G., DiMaio, F., Baker, D., Gonen, T.
登録日2014-06-11
公開日2014-10-15
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献High thermodynamic stability of parametrically designed helical bundles.
Science, 346, 2014
4UOS
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THERMODYNAMIC HYPERSTABILITY IN PARAMETRICALLY DESIGNED HELICAL BUNDLES
分子名称:DESIGNED HELICAL BUNDLE
著者Oberdorfer, G., Huang, P., Pei, X.Y., Xu, C., Gonen, T., Nannenga, B., DiMaio, D., Rogers, J., Luisi, B.F., Baker, D.
登録日2014-06-09
公開日2014-11-05
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
4UOT
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THERMODYNAMIC HYPERSTABILITY IN PARAMETRICALLY DESIGNED HELICAL BUNDLES
分子名称:DESIGNED HELICAL BUNDLE 5H2L
著者Oberdorfer, G., Huang, P., Pei, X.Y., Xu, C., Gonen, T., Nannenga, B., DiMaio, D., Rogers, J., Luisi, B.F., Baker, D.
登録日2014-06-09
公開日2014-11-05
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献High Thermodynamic Stability of Parametrically Designed Helical Bundles
Science, 346, 2014
4ZNN
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MICROED STRUCTURE OF THE SEGMENT, GVVHGVTTVA, FROM THE A53T FAMILIAL MUTANT OF PARKINSON'S DISEASE PROTEIN, ALPHA-SYNUCLEIN RESIDUES 47-56
分子名称:Alpha-synuclein
著者Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
登録日2015-05-05
公開日2015-09-09
最終更新日2017-09-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.41 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
5A3E
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2.5A STRUCTURE OF LYSOZYME DETERMINED BY MICROED WITH DATA FROM A SINGLE CRYSTAL
分子名称:LYSOZYME C
著者Nannenga, B.L., Shi, D., Leslie, A.G.W., Gonen, T.
登録日2015-05-28
公開日2015-06-17
最終更新日2017-04-19
実験手法ELECTRON CRYSTALLOGRAPHY (2.501 Å)
主引用文献High-Resolution Structure Determination by Continuous-Rotation Data Collection in Microed.
Nat.Methods, 11, 2014
5I9S
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MICROED STRUCTURE OF PROTEINASE K AT 1.75 A RESOLUTION
分子名称:Proteinase K, SULFATE ION
著者Hattne, J., Shi, D., de la Cruz, M.J., Reyes, F.E., Gonen, T.
登録日2016-02-20
公開日2016-06-08
最終更新日2018-08-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.75 Å)
主引用文献Modeling truncated pixel values of faint reflections in MicroED images.
J.Appl.Crystallogr., 49, 2016
5K7N
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MICROED STRUCTURE OF TAU VQIVYK PEPTIDE AT 1.1 A RESOLUTION
分子名称:VQIVYK
著者de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
登録日2016-05-26
公開日2017-04-05
最終更新日2018-08-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.1 Å)
主引用文献Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
5K7O
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MICROED STRUCTURE OF LYSOZYME AT 1.8 A RESOLUTION
分子名称:Lysozyme C, CHLORIDE ION, SODIUM ION
著者de la Cruz, M.J., Hattne, J., Shi, D., Seidler, P., Rodriguez, J., Reyes, F.E., Sawaya, M.R., Cascio, D., Eisenberg, D., Gonen, T.
登録日2016-05-26
公開日2017-04-05
最終更新日2018-08-22
実験手法ELECTRON CRYSTALLOGRAPHY (1.8 Å)
主引用文献Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017