Author results

2PZY
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STRUCTURE OF MK2 COMPLEXED WITH COMPOUND 76
分子名称:MAP kinase-activated protein kinase 2, (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, STAUROSPORINE
著者White, A., Wu, J.P., Wang, J., Abeywardane, A., Andersen, D., Emmanuel, M., Gautschi, E., Goldberg, D.R., Kashem, M.A., Lukas, S., Mao, W., Martin, L., Morwick, T., Moss, N., Pargellis, C., Patel, U.R., Patnaude, L., Peet, G.W., Skow, D., Snow, R.J., Ward, Y., Werneburg, B.
登録日2007-05-18
公開日2007-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
Bioorg.Med.Chem.Lett., 17, 2007
5WNE
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X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR
分子名称:Rho-associated protein kinase 1, 3,4-dimethoxy-N-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamide, GLYCEROL
著者Li, X.
登録日2017-07-31
公開日2018-08-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel mechanism of Rho kinase selectivity: beyond the ATP pocket
To Be Published
5WNF
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X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR
分子名称:Rho-associated protein kinase 1, 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-N-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)-1H-1,2,3-triazole-4-carboxamide, GLYCEROL
著者Li, X.
登録日2017-07-31
公開日2018-08-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Novel mechanism of Rho kinase selectivity: beyond the ATP pocket
To Be Published
5WNG
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X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR
分子名称:Rho-associated protein kinase 1, (2R)-N-(3-cyanophenyl)-2-(3-{[(6S)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamide
著者Li, X.
登録日2017-07-31
公開日2018-08-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Novel mechanism of Rho kinase selectivity: beyond the ATP pocket
To Be Published
5WNH
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X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR
分子名称:Rho-associated protein kinase 1, (2R)-N-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide
著者Li, X.
登録日2017-07-31
公開日2018-08-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Novel mechanism of Rho kinase selectivity: beyond the ATP pocket
To Be Published