5WRV | | COMPLEX STRUCTURE OF HUMAN SRP72/SRP68 | | Descriptor: | Signal recognition particle subunit SRP68, Signal recognition particle subunit SRP72, ACETATE ION, ... | | Authors: | Gao, Y., Chen, Z. | | Deposit date: | 2016-12-04 | | Release date: | 2017-06-21 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
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5WRW | | STRUCTURE OF HUMAN APO-SRP72 | | Descriptor: | Signal recognition particle subunit SRP72, SULFATE ION | | Authors: | Gao, Y., Chen, Z. | | Deposit date: | 2016-12-04 | | Release date: | 2017-06-21 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
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3UBU | | CRYSTAL STRUCTURE OF AGKISACUCETIN, A GPIB-BINDING SNACLEC (SNAKE C-TYPE LECTIN) THAT INHIBITS PLATELET | | Descriptor: | Agglucetin subunit alpha-1, Agglucetin subunit beta-2, SULFATE ION, ... | | Authors: | Gao, Y., Ge, H., Chen, H., Li, H., Liu, Y., Niu, L., Teng, M. | | Deposit date: | 2011-10-25 | | Release date: | 2012-04-11 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Crystal structure of agkisacucetin, a Gpib-binding snake C-type lectin that inhibits platelet adhesion and aggregation.
Proteins, 2012
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5IRX | | STRUCTURE OF TRPV1 IN COMPLEX WITH DKTX AND RTX, DETERMINED IN LIPID NANODISC | | Descriptor: | Transient receptor potential cation channel subfamily V member 1, Tau-theraphotoxin-Hs1a, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ... | | Authors: | Gao, Y., Cao, E., Julius, D., Cheng, Y. | | Deposit date: | 2016-03-14 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-13 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
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5IRZ | | STRUCTURE OF TRPV1 DETERMINED IN LIPID NANODISC | | Descriptor: | Transient receptor potential cation channel subfamily V member 1, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, ... | | Authors: | Gao, Y., Cao, E., Julius, D., Cheng, Y. | | Deposit date: | 2016-03-15 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-13 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
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5IS0 | | STRUCTURE OF TRPV1 IN COMPLEX WITH CAPSAZEPINE, DETERMINED IN LIPID NANODISC | | Descriptor: | Transient receptor potential cation channel subfamily V member 1, capsazepine | | Authors: | Gao, Y., Cao, E., Julius, D., Cheng, Y. | | Deposit date: | 2016-03-15 | | Release date: | 2016-05-25 | | Last modified: | 2017-09-13 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
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6N7I | | STRUCTURE OF BACTERIOPHAGE T7 E343Q MUTANT GP4 HELICASE-PRIMASE IN COMPLEX WITH SSDNA, DTTP, AC DINUCLEOTIDE AND CTP (GP4(5)-DNA) | | Descriptor: | DNA primase/helicase, DNA (25-MER), THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Gao, Y., Cui, Y., Zhou, Z., Yang, W. | | Deposit date: | 2018-11-27 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N7N | | STRUCTURE OF BACTERIOPHAGE T7 E343Q MUTANT GP4 HELICASE-PRIMASE IN COMPLEX WITH SSDNA, DTTP, AC DINUCLEOTIDE AND CTP (FORM I) | | Descriptor: | DNA primase/helicase, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Gao, Y., Cui, Y., Zhou, Z., Yang, W. | | Deposit date: | 2018-11-27 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N7S | | STRUCTURE OF BACTERIOPHAGE T7 E343Q MUTANT GP4 HELICASE-PRIMASE IN COMPLEX WITH SSDNA, DTTP, AC DINUCLEOTIDE AND CTP (FORM II) | | Descriptor: | DNA primase/helicase, DNA (25-MER), THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Gao, Y., Cui, Y., Zhou, Z., Yang, W. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N7T | | STRUCTURE OF BACTERIOPHAGE T7 E343Q MUTANT GP4 HELICASE-PRIMASE IN COMPLEX WITH SSDNA, DTTP, AC DINUCLEOTIDE AND CTP (FORM III) | | Descriptor: | DNA primase/helicase, DNA (25-MER), THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Gao, Y., Cui, Y., Zhou, Z., Yang, W. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9W | | STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) AND GP4 (HELICASE/PRIMASE) BOUND TO DNA INCLUDING RNA/DNA HYBRID, AND AN INCOMING DTTP (LAGS2) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, Primer, ... | | Authors: | Gao, Y., Cui, Y., Zhou, Z., Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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2DU9 | | CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL FACTOR FROM C.GLUTAMICUM | | Descriptor: | Predicted transcriptional regulators, (4S)-2-METHYL-2,4-PENTANEDIOL | | Authors: | Gao, Y., Yao, M., Tanaka, I. | | Deposit date: | 2006-07-20 | | Release date: | 2007-07-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | The structures of transcription factor CGL2947 from Corynebacterium glutamicum in two crystal forms: A novel homodimer assembling and the implication for effector-binding mode
Protein Sci., 16, 2007
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6N7V | | STRUCTURE OF BACTERIOPHAGE T7 GP4 (HELICASE-PRIMASE, E343Q MUTANT) IN COMPLEX WITH SSDNA, DTTP, AC DINUCLEOTIDE, AND CTP (FROM MULTIPLE LEAD COMPLEXES) | | Descriptor: | DNA primase/helicase, DNA (93-MER), THYMIDINE-5'-TRIPHOSPHATE, ... | | Authors: | Gao, Y., Fox, T., Val, N., Yang, W. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N7W | | STRUCTURE OF BACTERIOPHAGE T7 LEADING-STRAND DNA POLYMERASE (D5A/E7A)/TRX IN COMPLEX WITH A DNA FORK AND INCOMING DTTP (FROM MULTIPLE LEAD COMPLEXES) | | Descriptor: | DNA-directed DNA polymerase, TrxA, DNA (25-MER), ... | | Authors: | Gao, Y., Fox, T., Val, N., Yang, W. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9U | | STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) INTERACTING WITH PRIMASE DOMAINS OF TWO GP4 SUBUNITS BOUND TO AN RNA/DNA HYBRID AND DTTP (FROM LAGS1) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, RNA (5'-R(*AP*CP*CP*AP*G)-D(P*(DOC))-3'), ... | | Authors: | Gao, Y., Fox, T., Val, N., Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9V | | STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) AND GP4 (HELICASE/PRIMASE) BOUND TO DNA INCLUDING RNA/DNA HYBRID, AND AN INCOMING DTTP (LAGS1) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, Primer, ... | | Authors: | Gao, Y., Fox, T., Val, N., Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9X | | STRUCTURE OF BACTERIOPHAGE T7 LAGGING-STRAND DNA POLYMERASE (D5A/E7A) AND GP4 (HELICASE/PRIMASE) BOUND TO DNA INCLUDING RNA/DNA HYBRID, AND AN INCOMING DTTP (LAGS3) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, Primer, ... | | Authors: | Gao, Y., Fox, T., Val, N., Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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1CL4 | |
4GWS | | CRYSTAL STRUCTURE OF AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH FILLED CENTRAL CAVITY | | Descriptor: | Fructose-1,6-bisphosphatase 1, FRUCTOSE-6-PHOSPHATE, MAGNESIUM ION, ... | | Authors: | Gao, Y., Honzatko, R.B. | | Deposit date: | 2012-09-03 | | Release date: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fructose 2,6-bisphosphate Inhibition
To be Published
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4GWU | | CRYSTAL STRUCTURE OF FRU 2,6-BISPHOSPHATE COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH FILLED CENTRAL CAVITY | | Descriptor: | Fructose-1,6-bisphosphatase 1, FRUCTOSE-2,6-DIPHOSPHATE, MAGNESIUM ION | | Authors: | Gao, Y., Honzatko, R.B. | | Deposit date: | 2012-09-03 | | Release date: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fru 2,6-bisphosphate Inhibition
To be Published
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4GWW | |
4GWX | |
4GWY | |
4GWZ | |
4GX3 | |
