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ALPHA-KETO-ALDEHYDE BINDING MECHANISM REVEALS A NOVEL LEAD STRUCTURE MOTIF FOR PROTEASOME INHIBITION
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Groll, M., Poynor, M., Gallastegui, P., Stein, M., Schmidt, B., Kloetzel, P.M., Huber, R.
Deposit date:2010-08-25
Release date:2011-06-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition
Angew.Chem.Int.Ed.Engl., 50, 2011