Author results

2ZQE
  • Download 2zqe
  • View 2zqe
Molmil generated image of 2zqe
CRYSTAL STRUCTURE OF THE SMR DOMAIN OF THERMUS THERMOPHILUS MUTS2
Descriptor:MutS2 protein
Authors:Fukui, K., Kitamura, Y., Nakagawa, N., Masui, R., Kuramitsu, S.
Deposit date:2008-08-08
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression
J.Biol.Chem., 283, 2008
5B42
  • Download 5b42
  • View 5b42
Molmil generated image of 5b42
CRYSTAL STRUCTURE OF THE C-TERMINAL ENDONUCLEASE DOMAIN OF AQUIFEX AEOLICUS MUTL.
Descriptor:DNA mismatch repair protein MutL, CADMIUM ION, DI(HYDROXYETHYL)ETHER
Authors:Fukui, K., Baba, S., Kumasaka, T., Yano, T.
Deposit date:2016-03-30
Release date:2016-07-13
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural Features and Functional Dependency on beta-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL
J.Biol.Chem., 291, 2016
5X9Y
  • Download 5x9y
  • View 5x9y
Molmil generated image of 5x9y
CRYSTAL STRUCTURE OF THE ATPASE DOMAIN FROM BACTERIAL MISMATCH REPAIR ENDONUCLEASE AQUIFEX AEOLICUS MUTL.
Descriptor:DNA mismatch repair protein MutL, DI(HYDROXYETHYL)ETHER
Authors:Fukui, K., Yano, T.
Deposit date:2017-03-10
Release date:2017-08-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.443 Å)
Cite:Crystal structure and DNA-binding property of the ATPase domain of bacterial mismatch repair endonuclease MutL from Aquifex aeolicus
Biochim. Biophys. Acta, 1865, 2017
5Z41
  • Download 5z41
  • View 5z41
Molmil generated image of 5z41
AQUIFEX AEOLICUS MUTL ENDONUCLEASE DOMAIN WITH A SINGLE ZINC ION.
Descriptor:DNA mismatch repair protein MutL, ZINC ION, MAGNESIUM ION, ...
Authors:Fukui, K., Yano, T.
Deposit date:2018-01-10
Release date:2018-04-25
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Multiple zinc ions maintain the open conformation of the catalytic site in the DNA mismatch repair endonuclease MutL from Aquifex aeolicus
FEBS Lett., 592, 2018
5Z42
  • Download 5z42
  • View 5z42
Molmil generated image of 5z42
AQUIFEX AEOLICUS MUTL ENDONUCLEASE DOMAIN WITH THREE ZINC IONS.
Descriptor:DNA mismatch repair protein MutL, ZINC ION, SODIUM ION, ...
Authors:Fukui, K., Yano, T.
Deposit date:2018-01-10
Release date:2018-04-25
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Multiple zinc ions maintain the open conformation of the catalytic site in the DNA mismatch repair endonuclease MutL from Aquifex aeolicus
FEBS Lett., 592, 2018
3A4U
  • Download 3a4u
  • View 3a4u
Molmil generated image of 3a4u
CRYSTAL STRUCTURE OF MCFD2 IN COMPLEX WITH CARBOHYDRATE RECOGNITION DOMAIN OF ERGIC-53
Descriptor:Protein ERGIC-53, Multiple coagulation factor deficiency protein 2, CALCIUM ION, ...
Authors:Nishio, M., Kamiya, Y., Mizushima, T., Wakatsuki, S., Sasakawa, H., Yamamoto, K., Uchiyama, S., Noda, M., McKay, A.R., Fukui, K., Hauri, H.P., Kato, K.
Deposit date:2009-07-17
Release date:2010-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency.
Proc.Natl.Acad.Sci.USA, 107, 2010
3WJ4
  • Download 3wj4
  • View 3wj4
Molmil generated image of 3wj4
CRYSTAL STRUCTURE OF PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH TRIBUTYLTIN
Descriptor:Peroxisome proliferator-activated receptor gamma, tributylstannanyl
Authors:Harada, S., Hiromori, Y., Fukakusa, S., Kawahara, K., Nakamura, S., Noda, M., Uchiyama, S., Fukui, K., Nishikawa, J., Nagase, H., Kobayashi, Y., Ohkubo, T., Yoshida, T., Nakanishi, T.
Deposit date:2013-10-04
Release date:2014-10-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published
3WJ5
  • Download 3wj5
  • View 3wj5
Molmil generated image of 3wj5
CRYSTAL STRUCTURE OF PPARGAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH TRIPHENYLTIN
Descriptor:Peroxisome proliferator-activated receptor gamma, triphenylstannanyl
Authors:Harada, S., Hiromori, Y., Fukakusa, S., Kawahara, K., Nakamura, S., Noda, M., Uchiyama, S., Fukui, K., Nishikawa, J., Nagase, H., Kobayashi, Y., Ohkubo, T., Yoshida, T., Nakanishi, T.
Deposit date:2013-10-04
Release date:2014-10-15
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published
4U4P
  • Download 4u4p
  • View 4u4p
Molmil generated image of 4u4p
CRYSTAL STRUCTURE OF THE HUMAN CONDENSIN SMC HINGE DOMAIN HETERODIMER WITH SHORT COILED COILS
Descriptor:Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4
Authors:Uchiyama, S., Kawahara, K., Hosokawa, Y., Fukakusa, S., Oki, H., Nakamura, S., Noda, M., Takino, R., Miyahara, Y., Maruno, T., Kobayashi, Y., Ohkubo, T., Fukui, K.
Deposit date:2014-07-24
Release date:2015-08-26
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural basis for dimer information and DNA recognition of human SMC proteins
to be published
5XE8
  • Download 5xe8
  • View 5xe8
Molmil generated image of 5xe8
CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF STREPTOCOCCUS MUTANS COMA
Descriptor:Putative ABC transporter, ATP-binding protein ComA, DI(HYDROXYETHYL)ETHER
Authors:Ishii, S., Fukui, K., Yokoshima, S., Kumagai, K., Beniyama, Y., Kodama, T., Fukuyama, T., Okabe, T., Nagano, T., Kojima, H., Yano, T.
Deposit date:2017-04-03
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway
Sci Rep, 7, 2017
5XE9
  • Download 5xe9
  • View 5xe9
Molmil generated image of 5xe9
CRYSTAL STRUCTURE OF THE COMPLEX OF THE PEPTIDASE DOMAIN OF STREPTOCOCCUS MUTANS COMA WITH A SMALL MOLECULE INHIBITOR.
Descriptor:Putative ABC transporter, ATP-binding protein ComA, [(1~{S},2~{R},4~{S},5~{R})-5-[5-(4-methoxyphenyl)-2-methyl-pyrazol-3-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl ~{N}-propylcarbamate
Authors:Ishii, S., Fukui, K., Yokoshima, S., Kumagai, K., Beniyama, Y., Kodama, T., Fukuyama, T., Okabe, T., Nagano, T., Kojima, H., Yano, T.
Deposit date:2017-04-03
Release date:2017-06-28
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway
Sci Rep, 7, 2017
5YTP
  • Download 5ytp
  • View 5ytp
Molmil generated image of 5ytp
CRYSTAL STRUCTURE OF TTHA0139 L34A FROM THERMUS THERMOPHILUS HB8
Descriptor:TTHA0139
Authors:Takao, K., Inoue, M., Fukui, K., Yano, T., Masui, R.
Deposit date:2017-11-19
Release date:2018-11-21
Method:X-RAY DIFFRACTION (2.457 Å)
Cite:Crystal Structure of TTHA0139 L34A from Thermus thermophilus HB8
To Be Published
5YTQ
  • Download 5ytq
  • View 5ytq
Molmil generated image of 5ytq
CRYSTAL STRUCTURE OF TTHA0139 L34A WITH LANTHANUM FROM THERMUS THERMOPHILUS HB8
Descriptor:TTHA0139, LANTHANUM (III) ION
Authors:Takao, K., Inoue, M., Fukui, K., Yano, T., Masui, R.
Deposit date:2017-11-19
Release date:2018-11-21
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Crystal Structure of TTHA0139 L34A with Lanthanum from Thermus thermophilus HB8
To Be Published
5ZJ9
  • Download 5zj9
  • View 5zj9
Molmil generated image of 5zj9
HUMAN D-AMINO ACID OXIDASE COMPLEXED WITH 5-CHLOROTHIOPHENE-3-CARBOXYLIC ACID
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 5-chloro thiophene-3-carboxylic acid
Authors:Kato, Y., Hin, N., Maita, N., Thomas, A.G., Kurosawa, S., Rojas, C., Yorita, K., Slusher, B.S., Fukui, K., Tsukamoto, T.
Deposit date:2018-03-19
Release date:2018-10-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids
Eur J Med Chem, 159, 2018
5ZJA
  • Download 5zja
  • View 5zja
Molmil generated image of 5zja
HUMAN D-AMINO ACID OXIDASE COMPLEXED WITH 5-CHLOROTHIOPHENE-2-CARBOXYLIC ACID
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 5-chloro thiophene-2-carboxylic acid
Authors:Kato, Y., Hin, N., Maita, N., Thomas, A.G., Kurosawa, S., Rojas, C., Yorita, K., Slusher, B.S., Fukui, K., Tsukamoto, T.
Deposit date:2018-03-19
Release date:2018-10-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids
Eur J Med Chem, 159, 2018
2E48
  • Download 2e48
  • View 2e48
Molmil generated image of 2e48
CRYSTAL STRUCTURE OF HUMAN D-AMINO ACID OXIDASE: SUBSTRATE-FREE HOLOENZYME
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kawazoe, T., Tsuge, H., Imagawa, T., Fukui, K.
Deposit date:2006-12-05
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of d-DOPA oxidation by d-amino acid oxidase: Alternative pathway for dopamine biosynthesis.
Biochem.Biophys.Res.Commun., 355, 2007
2E49
  • Download 2e49
  • View 2e49
Molmil generated image of 2e49
CRYSTAL STRUCTURE OF HUMAN D-AMINO ACID OXIDASE IN COMPLEX WITH IMINO-SERINE
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 3-hydroxy-2-iminopropanoic acid
Authors:Kawazoe, T., Tsuge, H., Imagawa, T., Fukui, K.
Deposit date:2006-12-05
Release date:2007-03-06
Last modified:2011-11-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of d-DOPA oxidation by d-amino acid oxidase: Alternative pathway for dopamine biosynthesis.
Biochem.Biophys.Res.Commun., 355, 2007
2E4A
  • Download 2e4a
  • View 2e4a
Molmil generated image of 2e4a
CRYSTAL STRUCTURE OF HUMAN D-AMINO ACID OXIDASE IN COMPLEX WITH O-AMINOBENZOATE
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 2-AMINOBENZOIC ACID
Authors:Kawazoe, T., Tsuge, H., Imagawa, T., Fukui, K.
Deposit date:2006-12-05
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of d-DOPA oxidation by d-amino acid oxidase: Alternative pathway for dopamine biosynthesis.
Biochem.Biophys.Res.Commun., 355, 2007
2E82
  • Download 2e82
  • View 2e82
Molmil generated image of 2e82
CRYSTAL STRUCTURE OF HUMAN D-AMINO ACID OXIDASE COMPLEXED WITH IMINO-DOPA
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID
Authors:Kawazoe, T., Tsuge, H., Imagawa, T., Kuramitsu, S., Fukui, K.
Deposit date:2007-01-16
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of d-DOPA oxidation by d-amino acid oxidase: Alternative pathway for dopamine biosynthesis.
Biochem.Biophys.Res.Commun., 355, 2007
5X79
  • Download 5x79
  • View 5x79
Molmil generated image of 5x79
HUMAN GST PI CONJUGATED WITH NOVEL INHIBITOR, GS-ESF
Descriptor:Glutathione S-transferase P, (2S)-2-azanyl-5-[[(2R)-3-(2-fluorosulfonylethylsulfanyl)-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-propan-2-yl]amino]-5-oxidanylidene-pentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Tomoike, F., Shishido, Y., Fukui, K., Kimura, Y., Abe, H.
Deposit date:2017-02-24
Release date:2017-09-13
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A covalent G-site inhibitor for glutathione S-transferase Pi (GSTP1-1).
Chem. Commun. (Camb.), 53, 2017
2DU8
  • Download 2du8
  • View 2du8
Molmil generated image of 2du8
CRYSTAL STRUCTURE OF HUMAN D-AMINO ACID OXIDASE
Descriptor:D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE, BENZOIC ACID
Authors:Kawazoe, T., Tsuge, H., Fukui, K.
Deposit date:2006-07-20
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human D-amino acid oxidase: Context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring
Protein Sci., 15, 2006
2YZL
  • Download 2yzl
  • View 2yzl
Molmil generated image of 2yzl
CRYSTAL STRUCTURE OF PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE WITH ADP FROM METHANOCALDOCOCCUS JANNASCHII
Descriptor:Phosphoribosylaminoimidazole-succinocarboxamide synthase, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Kanagawa, M., Baba, S., Fukui, K., Kuramitsu, S., Yokoyama, S., Kawai, G., Sampei, G., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-06
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP from Methanocaldococcus jannaschii
To be Published
3AYT
  • Download 3ayt
  • View 3ayt
Molmil generated image of 3ayt
TTHB071 PROTEIN FROM THERMUS THERMOPHILUS HB8
Descriptor:Putative uncharacterized protein TTHB071, ZINC ION
Authors:Nakane, S., Wakamatsu, T., Fukui, K., Nakagawa, N., Masui, R., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2011-05-17
Release date:2011-10-19
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:In vivo, in vitro, and x-ray crystallographic analyses suggest the involvement of an uncharacterized triose-phosphate isomerase (TIM) barrel protein in protection against oxidative stress
J.Biol.Chem., 286, 2011
3AYV
  • Download 3ayv
  • View 3ayv
Molmil generated image of 3ayv
TTHB071 PROTEIN FROM THERMUS THERMOPHILUS HB8 SOAKING WITH ZNCL2
Descriptor:Putative uncharacterized protein TTHB071, ZINC ION
Authors:Nakane, S., Wakamatsu, T., Fukui, K., Nakagawa, N., Masui, R., Kuramitsu, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2011-05-17
Release date:2011-10-19
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:In vivo, in vitro, and x-ray crystallographic analyses suggest the involvement of an uncharacterized triose-phosphate isomerase (TIM) barrel protein in protection against oxidative stress
J.Biol.Chem., 286, 2011
5H45
  • Download 5h45
  • View 5h45
Molmil generated image of 5h45
CRYSTAL STRUCTURE OF THE C-TERMINAL LON PROTEASE-LIKE DOMAIN OF THERMUS THERMOPHILUS RADA/SMS
Descriptor:DNA repair protein RadA
Authors:Inoue, M., Fukui, K., Fujii, Y., Nakagawa, N., Yano, T., Kuramitsu, S., Masui, R.
Deposit date:2016-10-30
Release date:2017-05-03
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Lon protease-like domain in the bacterial RecA paralog RadA is required for DNA binding and repair.
J. Biol. Chem., 292, 2017
<12>