Author results

2FVY
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HIGH RESOLUTION GLUCOSE BOUND CRYSTAL STRUCTURE OF GGBP
Descriptor:D-galactose-binding periplasmic protein, BETA-D-GLUCOSE, CALCIUM ION, ...
Authors:Borrok, M.J., Kiessling, L.L., Forest, K.T.
Deposit date:2006-01-31
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
3TRV
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CRYSTAL STRUCTURE OF QUASIRACEMIC VILLIN HEADPIECE SUBDOMAIN CONTAINING (F5PHE17) SUBSTITUTION
Descriptor:L-Villin-1, D-Villin-1, SULFATE ION, ...
Authors:Mortenson, D.E., Satyshur, K.A., Gellman, S.H., Forest, K.T.
Deposit date:2011-09-11
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
J.Am.Chem.Soc., 134, 2012
4RWC
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RACEMIC M2-TM CRYSTALLIZED FROM RACEMIC DETERGENT
Descriptor:Matrix protein 2, B-OCTYLGLUCOSIDE
Authors:Mortenson, D.E., Steinkruger, J.D., Kreitler, D.F., Gellman, S.H., Forest, K.T.
Deposit date:2014-12-02
Release date:2015-10-14
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:High-resolution structures of a heterochiral coiled coil.
Proc.Natl.Acad.Sci.USA, 112, 2015
5I1S
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VILLIN HEADPIECE SUBDOMAIN WITH A LYS30 TO APC SUBSTITUTION
Descriptor:Villin-1, D-Villin headpiece subdomain
Authors:Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T.
Deposit date:2016-02-05
Release date:2016-05-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
3IPN
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CRYSTAL STRUCTURE OF FLUORINE AND METHYL MODIFIED COLLAGEN: (MEPFLPGLY)7
Descriptor:Non-natural Collagen, CARBONATE ION
Authors:Satyshur, K.A., Shoulders, M.D., Raines, R.T., Forest, K.T.
Deposit date:2009-08-18
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Stereoelectronic and steric effects in side chains preorganize a protein main chain.
Proc.Natl.Acad.Sci.USA, 107, 2010
3S7O
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CRYSTAL STRUCTURE OF THE INFRARED FLUORESCENT D207H VARIANT OF DEINOCOCCUS BACTERIOPHYTOCHROME CHROMOPHORE BINDING DOMAIN AT 1.24 ANGSTROM RESOLUTION
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, GLYCEROL
Authors:Forest, K.T., Auldridge, M.E., Satyshur, K.A., Anstrom, D.M.
Deposit date:2011-05-26
Release date:2011-12-21
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structure-guided engineering enhances a phytochrome-based infrared fluorescent protein.
J.Biol.Chem., 287, 2012
4HJB
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GCN4PLI DERIVATIVE WITH ALPHA/BETA/CYCLIC-GAMMA AMINO ACID SUBSTITUTION PATTERN
Descriptor:GCN4pLI(alpha/beta/cyclic-gamma)
Authors:Shin, Y.H., Mortenson, D.E., Satyshur, K.A., Forest, K.T., Gellman, S.H.
Deposit date:2012-10-12
Release date:2013-06-12
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Differential Impact of beta and gamma Residue Preorganization on alpha / beta / gamma-Peptide Helix Stability in Water.
J.Am.Chem.Soc., 135, 2013
6O4M
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RACEMIC MELITTIN
Descriptor:D-Melittin, Melittin, SULFATE ION
Authors:Kurgan, K.W., Bingman, C.A., Gellman, S.H., Forest, K.T.
Deposit date:2019-02-28
Release date:2019-05-22
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Retention of Native Quaternary Structure in Racemic Melittin Crystals.
J.Am.Chem.Soc., 141, 2019
1OQV
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STRUCTURE OF TCPA, THE TYPE IV PILIN SUBUNIT FROM THE TOXIN CO-REGULATED PILUS OF VIBRIO CHOLERAE CLASSICAL BIOTYPE
Descriptor:toxin-coregulated pilus subunit, GLYCEROL
Authors:Craig, L., Tainer, J.A.
Deposit date:2003-03-11
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Type IV Pilin Structure and Assembly: X-Ray and EM Analyses of Vibrio cholerae Toxin-Coregulated Pilus and Pseudomonas aeruginosa PAK Pilin
Mol.Cell, 11, 2003
4Z1W
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CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME MUTANT D207L Y263F FROM SYNCHROTRON
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Bhattacharya, S., Satyshur, K.A., Wangkanont, K., Lehtivuori, H., Forest, K.T.
Deposit date:2015-03-27
Release date:2016-01-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015
5I1N
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VILLIN HEADPIECE SUBDOMAIN WITH A GLN26 TO BETA-3-HOMOGLUTAMINE SUBSTITUTION
Descriptor:Villin-1, D-Villin headpiece subdomain
Authors:Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T.
Deposit date:2016-02-05
Release date:2016-05-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
5I1O
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VILLIN HEADPIECE SUBDOMAIN WITH A GLN26 TO ACPC SUBSTITUTION
Descriptor:Villin-1, D-Villin headpiece subdomain
Authors:Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T.
Deposit date:2016-02-05
Release date:2016-05-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.348 Å)
Cite:Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
3BKR
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CRYSTAL STRUCTURE OF STEROL CARRIER PROTEIN-2 LIKE-3 (SCP2-L3) FROM AEDES AEGYPTI
Descriptor:Sterol Carrier Protein-2 like-3, PALMITIC ACID
Authors:Dyer, D.H., Lan, Q., Forest, K.T.
Deposit date:2007-12-07
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Characterization of the yellow fever mosquito sterol carrier protein-2 like 3 gene and ligand-bound protein structure.
Mol.Cell.Biochem., 326, 2009
4XJJ
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EXTRACELLULAR DOMAIN OF TYPE II TRANSFORMING GROWTH FACTOR BETA RECEPTOR IN COMPLEX WITH 2-(2-HYDROXYETHYL)NDSB-201
Descriptor:TGF-beta receptor type-2, 3-[2-(2-hydroxyethyl)pyridinium-1-yl]propane-1-sulfonate
Authors:Wangkanont, K., Forest, K.T., Kiessling, L.L.
Deposit date:2015-01-08
Release date:2015-06-24
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201
to be published
5I1P
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VILLIN HEADPIECE SUBDOMAIN WITH A LYS30 TO BETA-3-HOMOLYSINE SUBSTITUTION
Descriptor:Villin-1, D-Villin headpiece subdomain, ETHANOL
Authors:Kreitler, D.F., Mortenson, D.E., Gellman, S.H., Forest, K.T.
Deposit date:2016-02-05
Release date:2016-05-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Effects of Single alpha-to-beta Residue Replacements on Structure and Stability in a Small Protein: Insights from Quasiracemic Crystallization.
J.Am.Chem.Soc., 138, 2016
6MPM
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RACEMIC M2-TM I42A CRYSTALLIZED FROM RACEMIC DETERGENT
Descriptor:Matrix protein 2, B-OCTYLGLUCOSIDE
Authors:Kreitler, D.F., Yao, Z., Mortenson, D.E., Forest, K.T., Gellman, S.H.
Deposit date:2018-10-07
Release date:2019-01-30
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
6MPN
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RACEMIC M2-TM I42E CRYSTALLIZED FROM RACEMIC DETERGENT
Descriptor:Matrix protein 2, B-OCTYLGLUCOSIDE
Authors:Kreitler, D.F., Yao, Z., Mortenson, D.E., Forest, K.T., Gellman, S.H.
Deposit date:2018-10-07
Release date:2019-01-30
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.
J. Am. Chem. Soc., 141, 2019
5U4B
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WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 3-[(1E)-2-(4-HYDROXYPHENYL)ETHENYL]BENZOIC ACID
Descriptor:Transthyretin, 3-[(E)-2-(4-hydroxyphenyl)ethenyl]benzoic acid
Authors:Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T.
Deposit date:2016-12-03
Release date:2017-09-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.448 Å)
Cite:Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
2O9C
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CRYSTAL STRUCTURE OF BACTERIOPHYTOCHROME CHROMOPHORE BINDING DOMAIN AT 1.45 ANGSTROM RESOLUTION
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Wagner, J.R., Brunzelle, J.S., Vierstra, R.D., Forest, K.T.
Deposit date:2006-12-13
Release date:2007-03-06
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High resolution structure of deinococcus bacteriophytochrome yields new insights into phytochrome architecture and evolution.
J.Biol.Chem., 282, 2007
5U4E
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WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 3-[(1E)-2-(2-CHLORO-4-BORONIC ACID)ETHENYL]BENZOIC ACID
Descriptor:Transthyretin, 3-[(E)-2-(4-borono-2-chlorophenyl)ethenyl]benzoic acid
Authors:Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T.
Deposit date:2016-12-03
Release date:2017-09-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
6NIV
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RACEMIC PHENOL-SOLUBLE MODULIN ALPHA 3 PEPTIDE
Descriptor:Phenol-soluble modulin PSM-alpha-3
Authors:Yao, Z., Cary, B.P., Bingman, C.A., Wang, C., Kreitler, D.F., Satyshur, K.A., Forest, K.T., Gellman, S.H.
Deposit date:2018-12-31
Release date:2019-05-15
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin alpha 3 Toxicity.
J.Am.Chem.Soc., 141, 2019
3TJW
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CRYSTAL STRUCTURE OF QUASIRACEMIC VILLIN HEADPIECE SUBDOMAIN CONTAINING (F5PHE10) SUBSTITUTION
Descriptor:D-Villin-1, L-Villin-1, SULFATE ION
Authors:Mortenson, D.E., Satyshur, K.A., Gellman, S.H., Forest, K.T.
Deposit date:2011-08-25
Release date:2012-01-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Quasiracemic crystallization as a tool to assess the accommodation of noncanonical residues in nativelike protein conformations.
J.Am.Chem.Soc., 134, 2012
4ZRR
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CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME MUTANT D207L Y263F AT 1.5 A RESOLUTION USING A HOME SOURCE.
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
Authors:Bhattacharya, S., Satyshur, K.A., Lehtivuori, H., Forest, K.T.
Deposit date:2015-05-12
Release date:2016-01-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015
5CGO
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STRUCTURE OF QUASIRACEMIC ALA-MAGAININ 2 WITH A BETA AMINO ACID SUBSTITUTION AT POSITION 13
Descriptor:ACPC-13 derivative of Ala-Magainin 2, D-Ala-Magainin 2
Authors:Hayouka, Z., Thomas, N.C., Mortenson, D.E., Satyshur, K.A., Weisblum, B., Forest, K.T., Gellman, S.H.
Deposit date:2015-07-09
Release date:2015-09-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.
J.Am.Chem.Soc., 137, 2015
5U48
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WILD-TYPE TRANSTHYRETIN IN COMPLEX WITH 5-[(1E)-2-(4-BORONIC ACID)ETHENYL]-1,3-BENZENEDIOL
Descriptor:Transthyretin, {4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl}boronic acid
Authors:Windsor, I.W., Smith, T.P., Raines, R.T., Forest, K.T.
Deposit date:2016-12-03
Release date:2017-09-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017