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1WKD
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TRNA-GUANINE TRANSGLYCOSYLASE
Descriptor:TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Romier, C., Reuter, K., Suck, D., Ficner, R.
Deposit date:1996-08-06
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
1WKE
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TRNA-GUANINE TRANSGLYCOSYLASE
Descriptor:TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Romier, C., Reuter, K., Suck, D., Ficner, R.
Deposit date:1996-08-06
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
1WKF
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TRNA-GUANINE TRANSGLYCOSYLASE
Descriptor:TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Romier, C., Reuter, K., Suck, D., Ficner, R.
Deposit date:1996-08-06
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
1PUD
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TRNA-GUANINE TRANSGLYCOSYLASE
Descriptor:TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION
Authors:Romier, C., Reuter, K., Suck, D., Ficner, R.
Deposit date:1996-06-28
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange.
EMBO J., 15, 1996
1E7K
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CRYSTAL STRUCTURE OF THE SPLICEOSOMAL 15.5KD PROTEIN BOUND TO A U4 SNRNA FRAGMENT
Descriptor:15.5 KD RNA BINDING PROTEIN, RNA (5'-R(*GP*CP*CP*AP*AP*UP*GP*AP*GP*GP*UP*UP*UP* AP*UP*CP*CP*GP*AP*GP*G*C(-3')
Authors:Vidovic, I., Nottrott, S., Harthmuth, K., Luhrmann, R., Ficner, R.
Deposit date:2000-08-29
Release date:2001-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment
Mol.Cell, 6, 2000
1XK5
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CRYSTAL STRUCTURE OF THE M3G-CAP-BINDING DOMAIN OF SNURPORTIN1 IN COMPLEX WITH A M3GPPPG-CAP DINUCLEOTIDE
Descriptor:snurportin-1, 2,2,7-TRIMETHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE
Authors:Strasser, A., Dickmanns, A., Luehrmann, R., Ficner, R.
Deposit date:2004-09-27
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for m(3)G-cap-mediated nuclear import of spliceosomal UsnRNPs by snurportin1
Embo J., 24, 2005
1QGV
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HUMAN SPLICEOSOMAL PROTEIN U5-15KD
Descriptor:SPLICEOSOMAL PROTEIN U5-15KD
Authors:Reuter, K., Nottrott, S., Fabrizio, P., Luehrmann, R., Ficner, R.
Deposit date:1999-05-06
Release date:1999-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15 kD protein.
J.Mol.Biol., 294, 1999
5DIS
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CRYSTAL STRUCTURE OF A CRM1-RANGTP-SPN1 EXPORT COMPLEX BOUND TO A 113 AMINO ACID FG-REPEAT CONTAINING FRAGMENT OF NUP214
Descriptor:Exportin-1, GTP-binding nuclear protein Ran, Snurportin-1, ...
Authors:Monecke, T., Port, S.A., Dickmanns, A., Kehlenbach, R.H., Ficner, R.
Deposit date:2015-09-01
Release date:2015-11-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015
1EFZ
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MUTAGENESIS AND CRYSTALLOGRAPHIC STUDIES OF ZYMOMONAS MOBILIS TRNA-GUANINE TRANSGLYCOSYLASE TO ELUCIDATE THE ROLE OF SERINE 103 FOR ENZYMATIC ACTIVITY
Descriptor:TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION, 7-DEAZA-7-AMINOMETHYL-GUANINE
Authors:Gradler, U., Ficner, R., Garcia, G.A., Stubbs, M.T., Klebe, G., Reuter, K.
Deposit date:2000-02-11
Release date:2000-03-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase to elucidate the role of serine 103 for enzymatic activity.
FEBS Lett., 454, 1999
1QR0
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CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX
Descriptor:4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, MAGNESIUM ION, COENZYME A
Authors:Reuter, K., Mofid, R.M., Marahiel, A.M., Ficner, R.
Deposit date:1999-06-17
Release date:1999-12-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily.
EMBO J., 18, 1999
3FGR
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TWO CHAIN FORM OF THE 66.3 KDA PROTEIN AT 1.8 ANGSTROEM
Descriptor:Putative phospholipase B-like 2 28 kDa form, Putative phospholipase B-like 2 40 kDa form, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lakomek, K., Dickmanns, A., Ficner, R.
Deposit date:2008-12-08
Release date:2009-09-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography
Bmc Struct.Biol., 9, 2009
3FGT
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TWO CHAIN FORM OF THE 66.3 KDA PROTEIN FROM MOUSE LACKING THE LINKER PEPTIDE
Descriptor:Putative phospholipase B-like 2 28 kDa form, Putative phospholipase B-like 2 40 kDa form, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lakomek, K., Dickmanns, A., Ficner, R.
Deposit date:2008-12-08
Release date:2009-09-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography
Bmc Struct.Biol., 9, 2009
3FGW
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ONE CHAIN FORM OF THE 66.3 KDA PROTEIN
Descriptor:Putative phospholipase B-like 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Lakomek, K., Dickmanns, A., Ficner, R.
Deposit date:2008-12-08
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography
Bmc Struct.Biol., 9, 2009
1ALL
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ALLOPHYCOCYANIN
Descriptor:ALLOPHYCOCYANIN, PHYCOCYANOBILIN
Authors:Brejc, K., Ficner, R., Huber, R., Steinbacher, S.
Deposit date:1995-03-01
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Isolation, crystallization, crystal structure analysis and refinement of allophycocyanin from the cyanobacterium Spirulina platensis at 2.3 A resolution.
J.Mol.Biol., 249, 1995
1MZW
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CRYSTAL STRUCTURE OF A U4/U6 SNRNP COMPLEX BETWEEN HUMAN SPLICEOSOMAL CYCLOPHILIN H AND A U4/U6-60K PEPTIDE
Descriptor:U-snRNP-associated cyclophilin, U4/U6 snrnp 60kDa protein
Authors:Reidt, U., Wahl, M.C., Horowitz, D.S., Luehrmann, R., Ficner, R.
Deposit date:2002-10-10
Release date:2003-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide
J.Mol.Biol., 331, 2003
1QOI
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U4/U6 SNRNP-SPECIFIC CYCLOPHILIN SNUCYP-20
Descriptor:SNUCYP-20
Authors:Reidt, U., Reuter, K., Achsel, T., Ingelfinger, D., Luehrmann, R., Ficner, R.
Deposit date:1999-11-09
Release date:2000-04-10
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human U4/U6 Small Nuclear Ribonucleoproteinparticle-Specificsnucyp-20, a Nuclear Cyclophilin
J.Biol.Chem., 275, 2000
1SYX
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THE CRYSTAL STRUCTURE OF A BINARY U5 SNRNP COMPLEX
Descriptor:Spliceosomal U5 snRNP-specific 15 kDa protein, CD2 antigen cytoplasmic tail-binding protein 2
Authors:Nielsen, T.K., Liu, S., Luhrmann, R., Ficner, R.
Deposit date:2004-04-02
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.345 Å)
Cite:Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2).
J.Mol.Biol., 369, 2007
1V0E
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ENDOSIALIDASE OF BACTERIOPHAGE K1F
Descriptor:ENDO-ALPHA-SIALIDASE, PHOSPHATE ION
Authors:Stummeyer, K., Dickmanns, A., Muehlenhoff, M., Gerady-Schahn, R., Ficner, R.
Deposit date:2004-03-28
Release date:2004-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Nat.Struct.Mol.Biol., 12, 2005
1V0F
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ENDOSIALIDASE OF BACTERIOPHAGE K1F IN COMPLEX WITH OLIGOMERIC ALPHA-2,8-SIALIC ACID
Descriptor:ENDO-ALPHA-SIALIDASE, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, PHOSPHATE ION, ...
Authors:Stummeyer, K., Dickmanns, A., Muehlenhoff, M., Gerady-Schahn, R., Ficner, R.
Deposit date:2004-03-28
Release date:2004-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F
Nat.Struct.Mol.Biol., 12, 2005
3EWI
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STRUCTURAL ANALYSIS OF THE C-TERMINAL DOMAIN OF MURINE CMP-SIALIC ACID SYNTHETASE
Descriptor:N-acylneuraminate cytidylyltransferase
Authors:Oschlies, M., Dickmanns, A., Stummeyer, K., Gerardy-Schahn, R., Ficner, R., Muenster-Kuehnel, A.K.
Deposit date:2008-10-15
Release date:2009-08-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
J.Mol.Biol., 393, 2009
3JU4
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CRYSTAL STRUCTURE ANALYSIS OF ENDOSIALIDASENF AT 0.98 A RESOLUTION
Descriptor:Endo-N-acetylneuraminidase, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, CHLORIDE ION, ...
Authors:Schulz, E.C., Neuman, P., Gerardy-Schahn, R., Sheldrick, G.M., Ficner, R.
Deposit date:2009-09-14
Release date:2010-02-02
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Structure analysis of endosialidase NF at 0.98 A resolution.
Acta Crystallogr.,Sect.D, 66, 2010
4KXY
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HUMAN TRANSKETOLASE IN COMPLEX WITH THDP ANALOGUE (R)-2-(1,2-DIHYDROXYETHYL)-3-DEAZA-THDP
Descriptor:Transketolase, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Neumann, P., Luedtke, S., Erixon, K.M., Leeper, F., Kluger, R., Ficner, R., Tittmann, K.
Deposit date:2013-05-28
Release date:2013-08-21
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
4NHO
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STRUCTURE OF THE SPLICEOSOMAL DEAD-BOX PROTEIN PRP28
Descriptor:Probable ATP-dependent RNA helicase DDX23, SULFATE ION, GLYCEROL, ...
Authors:Moehlmann, S., Neumann, P., Ficner, R.
Deposit date:2013-11-05
Release date:2014-06-18
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28.
Acta Crystallogr.,Sect.D, 70, 2014
4O1J
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CRYSTAL STRUCTURES OF TWO TETRAMERIC BETA-CARBONIC ANHYDRASES FROM THE FILAMENTOUS ASCOMYCETE SORDARIA MACROSPORA.
Descriptor:Carbonic anhydrase, ZINC ION, CHLORIDE ION
Authors:Lehneck, R., Neumann, P., Vullo, D., Elleuche, S., Supuran, C.T., Ficner, R., Poggeler, S.
Deposit date:2013-12-16
Release date:2014-03-05
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.695 Å)
Cite:Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora.
Febs J., 281, 2014
4O1K
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CRYSTAL STRUCTURES OF TWO TETRAMERIC BETA-CARBONIC ANHYDRASES FROM THE FILAMENTOUS ASCOMYCETE SORDARIA MACROSPORA.
Descriptor:Carbonic anhydrase, ZINC ION
Authors:Lehneck, R., Neumann, P., Vullo, D., Elleuche, S., Supuran, C.T., Ficner, R., Poggeler, S.
Deposit date:2013-12-16
Release date:2014-03-05
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora.
Febs J., 281, 2014