Author results

3HNC
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE 1 BOUND TO THE EFFECTOR TTP
Descriptor:Ribonucleoside-diphosphate reductase large subunit, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Fairman, J.W., Wijerathna, S.R., Xu, H., Dealwis, C.G.
Deposit date:2009-05-31
Release date:2011-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
3HND
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE 1 BOUND TO THE EFFECTOR TTP AND SUBSTRATE GDP
Descriptor:Ribonucleoside-diphosphate reductase large subunit, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Fairman, J.W., Wijerathna, S.R., Xu, H., Dealwis, C.G.
Deposit date:2009-05-31
Release date:2011-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
3HNE
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE 1 BOUND TO THE EFFECTORS TTP AND ATP
Descriptor:Ribonucleoside-diphosphate reductase large subunit, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Fairman, J.W., Wijerathna, S.R., Xu, H., Dealwis, C.G.
Deposit date:2009-05-31
Release date:2011-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
3HNF
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE 1 BOUND TO THE EFFECTORS TTP AND DATP
Descriptor:Ribonucleoside-diphosphate reductase large subunit, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Fairman, J.W., Wijerathna, S.R., Xu, H., Dealwis, C.G.
Deposit date:2009-05-31
Release date:2011-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
3PAW
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LOW RESOLUTION X-RAY CRYSTAL STRUCTURE OF YEAST RNR1P WITH DATP BOUND IN THE A-SITE
Descriptor:Ribonucleoside-diphosphate reductase large chain 1
Authors:Fairman, J.W., Wijerathna, S.R., Dealwis, C.G.
Deposit date:2010-10-19
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (6.61 Å)
Cite:Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011
4E1S
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X-RAY CRYSTAL STRUCTURE OF THE TRANSMEMBRANE BETA-DOMAIN FROM INTIMIN FROM EHEC STRAIN O157:H7
Descriptor:Intimin, CHLORIDE ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Fairman, J.W., Dautin, N., Wojtowicz, D., Wei, L., Noinaj, N., Barnard, T.J., Udho, E., Finkelstein, A., Przytycka, T.M., Cherezov, V., Buchanan, S.K.
Deposit date:2012-03-07
Release date:2012-06-13
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (1.855 Å)
Cite:Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis.
Structure, 20, 2012
4E1T
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X-RAY CRYSTAL STRUCTURE OF THE TRANSMEMBRANE BETA-DOMAIN FROM INVASIN FROM YERSINIA PSEUDOTUBERCULOSIS
Descriptor:Invasin, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Authors:Fairman, J.W., Dautin, N., Wojtowicz, D., Wei, L., Noinaj, N., Barnard, T.J., Udho, E., Finkelstein, A., Przytycka, T.M., Cherezov, V., Buchanan, S.K.
Deposit date:2012-03-07
Release date:2012-06-13
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.263 Å)
Cite:Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis.
Structure, 20, 2012
4PBC
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X-RAY CRYSTAL STRUCTURE OF A PUTATIVE D-AMINO ACID AMINOTRANSFERASE FROM BURKHOLDERIA CENOCEPACIA
Descriptor:D-amino acid aminotransferase, PHOSPHATE ION
Authors:Fairman, J.W., Abendroth, J., Edwards, T.E., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-04-12
Release date:2014-07-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of a putative D-amino acid aminotransferase from Burkholderia cenocepacia
To Be Published
4TM5
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X-RAY CRYSTAL STRUCTURE OF A D-AMINO ACID AMINOTRANSFERASE FROM BURKHOLDERIA THAILANDENSIS E264 BOUND TO THE CO-FACTOR PYRIDOXAL PHOSPHATE
Descriptor:D-amino acid aminotransferase
Authors:Fairman, J.W., Taylor, B.M., Edwards, T.E., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-05-31
Release date:2014-07-02
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:X-ray crystal structure of a D-amino acid aminotransferase from Burkholderia thailandensis E264 bound to the co-factor pyridoxal phosphate
To Be Published
4XIN
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X-RAY CRYSTAL STRUCTURE OF AN LPQH ORTHOLOGUE FROM MYCOBACTERIUM AVIUM
Descriptor:LpqH orthologue, SODIUM ION
Authors:Fairman, J.W., Abendroth, J., Lorimer, D., Edwards, T.E., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-01-07
Release date:2015-03-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:X-ray Crystal Structure of an LpqH orthologue from Mycobacterium avium
To Be Published
5DLC
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X-RAY CRYSTAL STRUCTURE OF A PYRIDOXINE 5-PRIME-PHOSPHATE SYNTHASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Pyridoxine 5'-phosphate synthase, PHOSPHATE ION
Authors:Fairman, J.W., Abendroth, J., Lorimer, D., Edwards, T.E., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-09-04
Release date:2015-09-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa
To Be Published
4P9A
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X-RAY CRYSTAL STRUCTURE OF PA PROTEIN FROM INFLUENZA STRAIN H7N9
Descriptor:Polymerase PA, GLYCEROL
Authors:Fairman, J.W., Moen, S.O., Clifton, M.C., Edwards, T.E., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-04-02
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1999 Å)
Cite:Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Sci Rep, 4, 2014
4PCA
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X-RAY CRYSTAL STRUCTURE OF AN O-METHYLTRANSFERASE FROM ANAPLASMA PHAGOCYTOPHILUM BOUND TO SAH AND MANGANESE
Descriptor:O-methyltransferase family protein, MANGANESE (II) ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Fairman, J.W., Abendroth, J., Lorimer, D., Edwards, T.E., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-04-14
Release date:2014-06-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum.
Plos Pathog., 11, 2015
4PCL
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X-RAY CRYSTAL STRUCTURE OF AN O-METHYLTRANSFERASE FROM ANAPLASMA PHAGOCYTOPHILUM BOUND TO SAM AND A MANGANESE ION.
Descriptor:O-methyltransferase family protein, S-ADENOSYLMETHIONINE, 1,2-ETHANEDIOL, ...
Authors:Fairman, J.W., Edwards, T.E., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-04-15
Release date:2014-06-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum.
Plos Pathog., 11, 2015
4YET
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X-RAY CRYSTAL STRUCTURE OF SUPEROXIDE DISMUTASE FROM BABESIA BOVIS SOLVED BY SULFUR SAD
Descriptor:Superoxide dismutase, FE (III) ION
Authors:Fairman, J.W., Clifton, M.C., Abendroth, J., Edwards, T.E., Lorimer, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2015-02-24
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Acta Crystallogr.,Sect.F, 71, 2015
1ZYZ
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STRUCTURES OF YEAST RIBONUCLOETIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, GLYCINE
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-13
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZZD
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, Ribonucleoside-diphosphate reductase small chain 2
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-13
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVT
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVU
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVV
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVW
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVX
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, MAGNESIUM ION, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVY
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STRUCTURES OF YEAST RIBONUCLEOTIDE REDUCTASE I
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, ...
Authors:Xu, H., Faber, C., Uchiki, T., Fairman, J.W., Racca, J., Dealwis, C.
Deposit date:2005-06-14
Release date:2006-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2ZLF
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THE STRUCTURAL BASIS FOR PEPTIDOMIMETIC INHIBITION OF EUKARYOTIC RIBONUCLEOTIDE REDUCTASE
Descriptor:Ribonucleoside-diphosphate reductase large chain 1, FTLDADF
Authors:Xu, H., Fairman, J.W., Wijerathna, S.R., LaMacchia, J., Kreischer, N.R., Helmbrecht, E., Cooperman, B.S., Dealwis, C.
Deposit date:2008-04-09
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008