Author results

1HE8
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RAS G12V - PI 3-KINASE GAMMA COMPLEX
Descriptor:PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT, GAMMA ISOFORM, TRANSFORMING PROTEIN P21/H-RAS-1, ...
Authors:Pacold, M.E., Suire, S., Perisic, O., Lara-Gonzalez, S., Davis, C.T., Hawkins, P.T., Walker, E.H., Stephens, L., Eccleston, J.F., Williams, R.L.
Deposit date:2000-11-20
Release date:2001-01-08
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structure and Functional Analysis of Ras Binding to its Effector Phosphoinositide 3-Kinase Gamma
Cell(Cambridge,Mass.), 103, 2000
1OW3
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CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH RHOGAP
Descriptor:Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ...
Authors:Graham, D.L., Lowe, P.N., Grime, G.W., Marsh, M., Rittinger, K., Smerdon, S.J., Gamblin, S.J., Eccleston, J.F.
Deposit date:2003-03-28
Release date:2003-05-06
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer
Chem.Biol., 9, 2002
1RGP
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GTPASE-ACTIVATION DOMAIN FROM RHOGAP
Descriptor:RHOGAP
Authors:Barrett, T., Xiao, B., Dodson, E.J., Dodson, G., Ludbrook, S.B., Nurmahomed, K., Gamblin, S.J., Musacchio, A., Smerdon, S.J., Eccleston, J.F.
Deposit date:1996-12-05
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of the GTPase-activating domain from p50rhoGAP.
Nature, 385, 1997
2NPR
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STRUCTURAL STUDIES ON PLASMODIUM VIVAX MEROZOITE SURFACE PROTEIN-1
Descriptor:Merozoite surface protein 1
Authors:Babon, J.J., Morgan, W.D., Kelly, G., Eccleston, J.F., Feeney, J., Holder, A.A.
Deposit date:2006-10-29
Release date:2007-03-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural studies on Plasmodium vivax merozoite surface protein-1
Mol.Biochem.Parasitol., 153, 2007
2V8Q
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-13
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-20
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2007-08-23
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2Y8L
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH TWO ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-07
Release date:2011-03-16
Last modified:2014-01-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH ONE ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-09
Release date:2011-03-16
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YA3
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2011-02-17
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
4CFH
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STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
Descriptor:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
Authors:Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
Deposit date:2013-11-18
Release date:2013-12-25
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
1AM4
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COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)
Descriptor:P50-RHOGAP, CDC42HS, MAGNESIUM ION, ...
Authors:Rittinger, K., Walker, P., Gamblin, S.J., Smerdon, S.J.
Deposit date:1997-06-22
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
Nature, 388, 1997
1MEP
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CRYSTAL STRUCTURE OF STREPTAVIDIN DOUBLE MUTANT S45A/D128A WITH BIOTIN: COOPERATIVE HYDROGEN-BOND INTERACTIONS IN THE STREPTAVIDIN-BIOTIN SYSTEM.
Descriptor:Streptavidin, BIOTIN
Authors:Hyre, D.E., Le Trong, I., Merritt, E.A., Stenkamp, R.E., Green, N.M., Stayton, P.S.
Deposit date:2002-08-08
Release date:2003-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Cooperative hydrogen bond interactions in the streptavidin-biotin system
Protein Sci., 15, 2006
1MK5
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WILDTYPE CORE-STREPTAVIDIN WITH BIOTIN AT 1.4A.
Descriptor:Streptavidin, BIOTIN
Authors:Hyre, D.E., Le Trong, I., Merritt, E.A., Green, N.M., Stenkamp, R.E., Stayton, P.S.
Deposit date:2002-08-28
Release date:2003-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cooperative hydrogen bond interactions in the streptavidin-biotin system
Protein Sci., 15, 2006
1TX4
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RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
Descriptor:P50-RHOGAP, TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, ...
Authors:Rittinger, K., Walker, P.A., Smerdon, S.J., Gamblin, S.J.
Deposit date:1997-07-29
Release date:1998-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997