Author results

1HE8
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RAS G12V - PI 3-KINASE GAMMA COMPLEX
分子名称:PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT, GAMMA ISOFORM, TRANSFORMING PROTEIN P21/H-RAS-1, ...
著者Pacold, M.E., Suire, S., Perisic, O., Lara-Gonzalez, S., Davis, C.T., Hawkins, P.T., Walker, E.H., Stephens, L., Eccleston, J.F., Williams, R.L.
登録日2000-11-20
公開日2001-01-08
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure and Functional Analysis of Ras Binding to its Effector Phosphoinositide 3-Kinase Gamma
Cell(Cambridge,Mass.), 103, 2000
1OW3
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CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH RHOGAP
分子名称:Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ...
著者Graham, D.L., Lowe, P.N., Grime, G.W., Marsh, M., Rittinger, K., Smerdon, S.J., Gamblin, S.J., Eccleston, J.F.
登録日2003-03-28
公開日2003-05-06
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer
Chem.Biol., 9, 2002
1RGP
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GTPASE-ACTIVATION DOMAIN FROM RHOGAP
分子名称:RHOGAP
著者Barrett, T., Xiao, B., Dodson, E.J., Dodson, G., Ludbrook, S.B., Nurmahomed, K., Gamblin, S.J., Musacchio, A., Smerdon, S.J., Eccleston, J.F.
登録日1996-12-05
公開日1997-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the GTPase-activating domain from p50rhoGAP.
Nature, 385, 1997
2NPR
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STRUCTURAL STUDIES ON PLASMODIUM VIVAX MEROZOITE SURFACE PROTEIN-1
分子名称:Merozoite surface protein 1
著者Babon, J.J., Morgan, W.D., Kelly, G., Eccleston, J.F., Feeney, J., Holder, A.A.
登録日2006-10-29
公開日2007-03-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural studies on Plasmodium vivax merozoite surface protein-1
Mol.Biochem.Parasitol., 153, 2007
2V8Q
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-13
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-20
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-23
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2Y8L
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH TWO ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-07
公開日2011-03-16
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH ONE ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-09
公開日2011-03-16
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YA3
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-17
公開日2011-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
4CFH
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STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2013-11-18
公開日2013-12-25
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
1AM4
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COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)
分子名称:P50-RHOGAP, CDC42HS, MAGNESIUM ION, ...
著者Rittinger, K., Walker, P., Gamblin, S.J., Smerdon, S.J.
登録日1997-06-22
公開日1998-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
Nature, 388, 1997
1MEP
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CRYSTAL STRUCTURE OF STREPTAVIDIN DOUBLE MUTANT S45A/D128A WITH BIOTIN: COOPERATIVE HYDROGEN-BOND INTERACTIONS IN THE STREPTAVIDIN-BIOTIN SYSTEM.
分子名称:Streptavidin, BIOTIN
著者Hyre, D.E., Le Trong, I., Merritt, E.A., Stenkamp, R.E., Green, N.M., Stayton, P.S.
登録日2002-08-08
公開日2003-09-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cooperative hydrogen bond interactions in the streptavidin-biotin system
Protein Sci., 15, 2006
1MK5
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WILDTYPE CORE-STREPTAVIDIN WITH BIOTIN AT 1.4A.
分子名称:Streptavidin, BIOTIN
著者Hyre, D.E., Le Trong, I., Merritt, E.A., Green, N.M., Stenkamp, R.E., Stayton, P.S.
登録日2002-08-28
公開日2003-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Cooperative hydrogen bond interactions in the streptavidin-biotin system
Protein Sci., 15, 2006
1TX4
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RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
分子名称:P50-RHOGAP, TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, ...
著者Rittinger, K., Walker, P.A., Smerdon, S.J., Gamblin, S.J.
登録日1997-07-29
公開日1998-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997