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2W1B
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THE STRUCTURE OF THE EFFLUX PUMP ACRB IN COMPLEX WITH BILE ACID
Descriptor:ACRIFLAVIN RESISTANCE PROTEIN B, (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID
Authors:Drew, D., Klepsch, M.M., Newstead, S., Flaig, R., De Gier, J.W., Iwata, S., Beis, K.
Deposit date:2008-10-17
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:The Structure of the Efflux Pump Acrb in Complex with Bile Acid.
Mol.Membr.Biol., 25, 2008
4ATV
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STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor:NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION, DODECYL-ALPHA-D-MALTOSIDE
Authors:Drew, D., Lee, C., Iwata, S., Cameron, A.D.
Deposit date:2012-05-10
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4AU5
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STRUCTURE OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor:NA(+)/H(+) ANTIPORTER NHAA, DODECYL-ALPHA-D-MALTOSIDE, SULFATE ION
Authors:Drew, D., Lee, C., Iwata, S., Cameron, A.D.
Deposit date:2012-05-14
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
2XUT
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CRYSTAL STRUCTURE OF A PROTON DEPENDENT OLIGOPEPTIDE (POT) FAMILY TRANSPORTER.
Descriptor:PROTON/PEPTIDE SYMPORTER FAMILY PROTEIN
Authors:Newstead, S., Drew, D., Cameron, A.D., Postis, V.L., Xia, X., Fowler, P.W., Ingram, J.C., Carpenter, E.P., Sansom, M.S.P., McPherson, M.J., Baldwin, S.A., Iwata, S.
Deposit date:2010-10-21
Release date:2010-12-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Crystal Structure of a Prokaryotic Homologue of the Mammalian Oligopeptide-Proton Symporters, Pept1 and Pept2.
Embo J., 30, 2011
3ZUX
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF THE BILE ACID SODIUM SYMPORTER ASBT.
Descriptor:TRANSPORTER, SODIUM ION, MERCURY (II) ION, ...
Authors:Hu, N.-J., Iwata, S., Cameron, A.D., Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
3ZUY
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CRYSTAL STRUCTURE OF A BACTERIAL HOMOLOGUE OF THE BILE ACID SODIUM SYMPORTER ASBT.
Descriptor:TRANSPORTER, SODIUM ION, TAUROCHOLIC ACID, ...
Authors:Hu, N.-J., Iwata, S., Cameron, A.D., Drew, D.
Deposit date:2011-07-21
Release date:2011-10-12
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
4APS
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CRYSTAL STRUCTURE OF A POT FAMILY PEPTIDE TRANSPORTER IN AN INWARD OPEN CONFORMATION.
Descriptor:DI-OR TRIPEPTIDE H+ SYMPORTER, CADMIUM ION
Authors:Solcan, N., Kwok, J., Fowler, P.W., Cameron, A.D., Drew, D., Iwata, S., Newstead, S.
Deposit date:2012-04-05
Release date:2012-06-13
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Alternating Access Mechanism in the Pot Family of Oligopeptide Transporters.
Embo J., 31, 2012
4BWZ
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CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER, NAPA
Descriptor:NA(+)/H(+) ANTIPORTER, ZINC ION
Authors:Lee, C., Drew, D., Cameron, A.D.
Deposit date:2013-07-05
Release date:2013-08-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:A two-domain elevator mechanism for sodium/proton antiport.
Nature, 501, 2013
4D1A
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH INDOLYLMETHYL-HYDANTOIN
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5S)-5-(1H-indol-3-ylmethyl)imidazolidine-2,4-dione, SODIUM ION
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1B
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BENZYL-HYDANTOIN
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5S)-5-benzylimidazolidine-2,4-dione, SODIUM ION
Authors:Brueckner, F., Geng, T., Weyand, S., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1C
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER, IN A CLOSED CONFORMATION WITH BROMOVINYLHYDANTOIN BOUND.
Descriptor:HYDANTOIN TRANSPORT PROTEIN, (5Z)-5-[(3-bromophenyl)methylidene]imidazolidine-2,4-dione, SODIUM ION
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4D1D
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STRUCTURE OF MHP1, A NUCLEOBASE-CATION-SYMPORT-1 FAMILY TRANSPORTER WITH THE INHIBITOR 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN.
Descriptor:HYDANTOIN TRANSPORT PROTEIN, 5-(2-NAPHTHYLMETHYL)-L-HYDANTOIN, 5-(2-NAPHTHYLMETHYL)-D-HYDANTOIN, ...
Authors:Weyand, S., Brueckner, F., Geng, T., Drew, D., Iwata, S., Henderson, P.J.F., Cameron, A.D.
Deposit date:2014-05-01
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Mechanism of Ligand Recognition by Membrane Transport Protein, Mhp1.
Embo J., 33, 2014
4YB9
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CRYSTAL STRUCTURE OF THE BOVINE FRUCTOSE TRANSPORTER GLUT5 IN AN OPEN INWARD-FACING CONFORMATION
Descriptor:Solute carrier family 2, facilitated glucose transporter member 5
Authors:Verdon, G., Kang, H.J., Iwata, S., Drew, D.
Deposit date:2015-02-18
Release date:2015-10-14
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and mechanism of the mammalian fructose transporter GLUT5.
Nature, 526, 2015
5BZ2
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CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION
Descriptor:Na(+)/H(+) antiporter
Authors:Coincon, M., Uzdavinys, P., Cameron, A., Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
5BZ3
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CRYSTAL STRUCTURE OF SODIUM PROTON ANTIPORTER NAPA IN OUTWARD-FACING CONFORMATION.
Descriptor:Na(+)/H(+) antiporter, (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE
Authors:Coincon, M., Uzdavinys, P., Emmanuel, N., Cameron, A., Drew, D.
Deposit date:2015-06-11
Release date:2016-01-20
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters.
Nat.Struct.Mol.Biol., 23, 2016
6I1R
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CRYSTAL STRUCTURE OF CMP BOUND CST IN AN OUTWARD FACING CONFORMATION
Descriptor:CMP-sialic acid transporter 1, CYTIDINE-5'-MONOPHOSPHATE
Authors:Nji, E., Gulati, A., Qureshi, A.A., Drew, D.
Deposit date:2018-10-30
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the delivery of activated sialic acid into Golgi for sialyation.
Nat.Struct.Mol.Biol., 2019
6I1Z
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OUTWARD FACING STRUCTURE OF APO CST
Descriptor:CMP-sialic acid transporter 1
Authors:Nji, E., Gulati, A., Qureshi, A.A., Drew, D.
Deposit date:2018-10-31
Release date:2019-06-05
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for the delivery of activated sialic acid into Golgi for sialyation.
Nat.Struct.Mol.Biol., 2019
4GKP
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STRUCTURE OF THE TRUNCATED NECK AND C-TERMINAL MOTOR HOMOLOGY DOMAIN OF VIK1 FROM CANDIDA GLABRATA
Descriptor:Spindle pole body-associated protein VIK1
Authors:Duan, D., Allingham, J.S.
Deposit date:2012-08-13
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1.
J.Biol.Chem., 287, 2012
4GKQ
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STRUCTURE OF THE NECK AND C-TERMINAL MOTOR HOMOLOGY DOMAIN OF VIK1 FROM CANDIDA GLABRATA
Descriptor:SPINDLE POLE BODY-ASSOCIATED PROTEIN VIK1
Authors:Duan, D., Allingham, J.S.
Deposit date:2012-08-13
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1.
J.Biol.Chem., 287, 2012
4GKR
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STRUCTURE OF THE C-TERMINAL MOTOR DOMAIN OF KAR3 FROM CANDIDA GLABRATA
Descriptor:Neck and C-terminal motor domain of Kar3, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Duan, D., Allingham, J.S.
Deposit date:2012-08-13
Release date:2012-10-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Neck Rotation and Neck Mimic Docking in the Noncatalytic Kar3-associated Protein Vik1.
J.Biol.Chem., 287, 2012
3AI4
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CRYSTAL STRUCTURE OF YEAST ENHANCED GREEN FLUORESCENT PROTEIN - MOUSE POLYMERASE IOTA UBIQUITIN BINDING MOTIF FUSION PROTEIN
Descriptor:yeast enhanced green fluorescent protein,DNA polymerase iota, SULFATE ION
Authors:Suzuki, N., Wakatsuki, S., Kawasaki, M.
Deposit date:2010-05-10
Release date:2010-09-29
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
3AI5
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CRYSTAL STRUCTURE OF YEAST ENHANCED GREEN FLUORESCENT PROTEIN-UBIQUITIN FUSION PROTEIN
Descriptor:yeast enhanced green fluorescent protein,Ubiquitin, 1,2-ETHANEDIOL
Authors:Suzuki, N., Wakatsuki, S., Kawasaki, M.
Deposit date:2010-05-10
Release date:2010-09-29
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
4YBQ
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RAT GLUT5 WITH FV IN THE OUTWARD-OPEN FORM
Descriptor:Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment light chain, ...
Authors:Nomura, N., Shimamura, T., Iwata, S.
Deposit date:2015-02-19
Release date:2015-10-07
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015