Author results

3DV3
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MEK1 WITH PF-04622664 BOUND
Descriptor:Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Kazmirski, S.L., Kothe, M., Ding, Y.-H.
Deposit date:2008-07-18
Release date:2009-07-21
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?
Bioorg.Med.Chem.Lett., 19, 2009
2RKU
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STRUCTURE OF PLK1 IN COMPLEX WITH BI2536
Descriptor:Serine/threonine-protein kinase PLK1, ZINC ION, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, ...
Authors:Ding, Y.-H., Kothe, M., Kohls, D., Low, S.
Deposit date:2007-10-17
Release date:2008-02-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Selectivity-determining residues in Plk1.
Chem.Biol.Drug Des., 70, 2007
2OU7
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN POLO-LIKE KINASE 1
Descriptor:Serine/threonine-protein kinase PLK1, ZINC ION, ACETATE ION, ...
Authors:Ding, Y.-H., Kothe, M., Kohls, D., Low, S.
Deposit date:2007-02-09
Release date:2007-04-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the catalytic domain of human polo-like kinase 1.
Biochemistry, 46, 2007
2OWB
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN POLO-LIKE KINASE 1
Descriptor:Serine/threonine-protein kinase PLK1, ZINC ION, ACETATE ION, ...
Authors:Ding, Y.-H., Kothe, M., Kohls, D., Low, S.
Deposit date:2007-02-15
Release date:2007-04-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the catalytic domain of human polo-like kinase 1.
Biochemistry, 46, 2007
1BNL
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ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN
Descriptor:COLLAGEN XVIII, ZINC ION
Authors:Ding, Y.-H., Javaherian, K., Lo, K.-M., Chopra, R., Boehm, T., Lanciotti, J., Harris, B.A., Li, Y., Shapiro, R., Hohenester, E., Timpl, R., Folkman, J., Wiley, D.C.
Deposit date:1998-07-30
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Zinc-dependent dimers observed in crystals of human endostatin.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BD2
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COMPLEX BETWEEN HUMAN T-CELL RECEPTOR B7, VIRAL PEPTIDE (TAX) AND MHC CLASS I MOLECULE HLA-A 0201
Descriptor:HLA-A 0201, BETA-2 MICROGLOBULIN, TAX PEPTIDE, ...
Authors:Ding, Y.-H., Smith, K.J., Garboczi, D.N., Utz, U., Biddison, W.E., Wiley, D.C.
Deposit date:1998-05-12
Release date:1998-08-19
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
Immunity, 8, 1998