Author results

1DVF
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IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX
Descriptor:FV D1.3, FV E5.2, ZINC ION
Authors:Braden, B.C., Fields, B.A., Ysern, X., Dall'Acqua, W., Goldbaum, F.A., Poljak, R.J., Mariuzza, R.A.
Deposit date:1996-04-13
Release date:1996-08-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution.
J.Mol.Biol., 264, 1996
1A2Y
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HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN), LYSOZYME, ...
Authors:Tsuchiya, D., Mariuzza, R.A.
Deposit date:1998-01-13
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
1KIP
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FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor:MONOCLONAL ANTIBODY D1.3, LYSOZYME
Authors:Fields, B.A., Poljak, R.J., Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIQ
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FV MUTANT Y(B 101)F (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor:MONOCLONAL ANTIBODY D1.3, LYSOZYME
Authors:Fields, B.A., Poljak, R.J., Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
1KIR
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FV MUTANT Y(A 50)S (VL DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor:MONOCLONAL ANTIBODY D1.3, LYSOZYME
Authors:Fields, B.A., Poljak, R.J., Mariuzza, R.A.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.
Biochemistry, 35, 1996
4UB0
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NEW DESIGN FOR MONOVALENT BISPECIFIC IGG THROUGH CYSTEINE ENGINEERING OF THE CH1-CL INTERFACE
Descriptor:IgG1, heavy chain, light chain
Authors:Oganesyan, V.Y., Dall'Acqua, W.F.
Deposit date:2014-08-11
Release date:2015-07-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improving target cell specificity using a novel monovalent bispecific IgG design.
Mabs, 7, 2015
6ATT
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39S FAB BOUND TO HER2 ECD
Descriptor:Receptor tyrosine-protein kinase erbB-2, Antibody 39S Fab heavy chain, Antibody 39S Fab light chain, ...
Authors:Oganesyan, V.Y., Dall'Acqua, W.F.
Deposit date:2017-08-29
Release date:2018-04-25
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.
J. Biol. Chem., 293, 2018
1VFA
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BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Bhat, T.N., Poljak, R.J.
Deposit date:1993-12-03
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Proc.Natl.Acad.Sci.USA, 91, 1994
1VFB
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BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN), HEN EGG WHITE LYSOZYME
Authors:Bhat, T.N., Poljak, R.J.
Deposit date:1993-12-03
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bound water molecules and conformational stabilization help mediate an antigen-antibody association.
Proc.Natl.Acad.Sci.USA, 91, 1994
1A7N
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7O
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R96L DELETION MUTANT ON VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7P
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) ENGINEERED MUTANT PRO95L->SER ON VARIANT CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN), ACETIC ACID
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7Q
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published
1A7R
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FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) VARIANT CHAIN L GLU81->ASP
Descriptor:IGG1-KAPPA D1.3 FV (LIGHT CHAIN), IGG1-KAPPA D1.3 FV (HEAVY CHAIN)
Authors:Marks, C., Henrick, K., Winter, G.
Deposit date:1998-03-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:X-Ray Structures of D1.3 Fv Mutants
To be Published