Author results

5FZT
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THE CRYSTAL STRUCTURE OF R7R8 IN COMPLEX WITH A DLC1 FRAGMENT.
Descriptor:TALIN-1, RHO GTPASE-ACTIVATING PROTEIN 7, MALONATE ION
Authors:Zacharchenko, T., Qian, X., Goult, B.T., Jethwa, D., Almeida, T., Ballestrem, C., Critchley, D.R., Lowy, D.R., Barsukov, I.L.
Deposit date:2016-03-15
Release date:2016-04-27
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex.
Structure, 24, 2016
1QKR
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CRYSTAL STRUCTURE OF THE VINCULIN TAIL AND A PATHWAY FOR ACTIVATION
Descriptor:VINCULIN, SULFATE ION
Authors:Bakolitsa, C., De Pereda, J.M., Bagshaw, C.R., Critchley, D.R., Liddington, R.C.
Deposit date:1999-08-04
Release date:2000-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Vinculin Tail and a Pathway for Activation
Cell(Cambridge,Mass.), 99, 1999
1SJ7
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CRYSTAL STRUCTURE OF TALIN ROD 482-655
Descriptor:Talin 1, PLATINUM (II) ION
Authors:Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-03-03
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
EMBO J., 23, 2004
1SJ8
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CRYSTAL STRUCTURE OF TALIN RESIDUES 482-789
Descriptor:Talin 1
Authors:Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-03-03
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
EMBO J., 23, 2004
1T01
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VINCULIN COMPLEXED WITH THE VBS1 HELIX FROM TALIN
Descriptor:unnamed protein product, Talin 1
Authors:Papagrigoriou, E., Gingras, A.R., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-04-07
Release date:2004-08-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
1U6H
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VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN VINCULIN BINDING SITE 2 (849-879)
Descriptor:Vinculin, Talin
Authors:Fillingham, I., Gingras, A.R., Papagrigoriou, E., Patel, B., Emsley, J., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2004-07-30
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1U89
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SOLUTION STRUCTURE OF VBS2 FRAGMENT OF TALIN
Descriptor:Talin 1
Authors:Fillingham, I., Gingras, A.R., Papagrigoriou, E., Patel, B., Emsley, J., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2004-08-05
Release date:2005-01-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1XWJ
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VINCULIN HEAD (1-258) IN COMPLEX WITH THE TALIN VINCULIN BINDING SITE 3 (1945-1969)
Descriptor:Vinculin, Talin
Authors:Gingras, A.R., Papagrigoriou, E., Barsukov, I.L., Critchley, D.R., Emsley, J.
Deposit date:2004-11-01
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
1Y19
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STRUCTURAL BASIS FOR PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE I-GAMMA BINDING TO TALIN AT FOCAL ADHESIONS
Descriptor:Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M., Wegener, K., Santelli, E., Bate, N., Ginsberg, M.H., Critchley, D.R., Campbell, I.D., Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
1ZVZ
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VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN ROD RESIDUE 820-844
Descriptor:Vinculin, Talin 1
Authors:Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW2
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VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN ROD RESIDUES 2345-2369
Descriptor:Vinculin, talin
Authors:Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW3
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VINCULIN HEAD (0-258) IN COMPLEX WITH THE TALIN ROD RESIDUES 1630-1652
Descriptor:Vinculin, Talin 1
Authors:Gingras, A.R., Ziegler, W.H., Barsukov, I.L., Roberts, G.C., Critchley, D.R., Emsley, J.
Deposit date:2005-06-03
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
2B0H
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SOLUTION STRUCTURE OF VBS3 FRAGMENT OF TALIN
Descriptor:Talin-1
Authors:Gingras, A.R., Vogel, K.P., Steinhoff, H.J., Ziegler, W.H., Patel, B., Emsley, J., Critchley, D.R., Roberts, G.C., Barsukov, I.L.
Deposit date:2005-09-14
Release date:2006-01-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
2KBB
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NMR STRUCTURE OF THE TALIN ROD DOMAIN, 1655-1822
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.
Deposit date:2008-11-24
Release date:2009-03-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KC1
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NMR STRUCTURE OF THE F0 DOMAIN (RESIDUES 0-85) OF THE TALIN FERM DOMAIN
Descriptor:MKIAA1027 protein
Authors:Goult, B.T., Elliott, P.R., Roberts, G.C.K., Critchley, D.R., Barsukov, I.L.
Deposit date:2008-12-13
Release date:2010-01-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 29, 2010
2KGX
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HADDOCK STRUCTURE OF THE TALIN F3 DOMAIN IN COMPLEX WITH TALIN 1655-1822
Descriptor:Talin-1, MKIAA1027 protein
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-03-23
Release date:2009-03-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The structure of an interdomain complex that regulates talin activity.
J.Biol.Chem., 284, 2009
2KMA
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NMR STRUCTURE OF THE F0F1 DOUBLE DOMAIN (RESIDUES 1-202) OF THE TALIN FERM DOMAIN
Descriptor:Talin 1
Authors:Goult, B.T., Elliott, P.R., Bate, N., Roberts, G.C., Critchley, D.R., Barsukov, I.L.
Deposit date:2009-07-25
Release date:2010-03-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.
Embo J., 2010
2KMC
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF KINDLIN-1
Descriptor:Fermitin family homolog 1
Authors:Goult, B.T., Bate, N., Roberts, G.C., Barsukov, I.L., Critchley, D.R.
Deposit date:2009-07-27
Release date:2009-10-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Structure of the N-Terminus of Kindlin-1: A Domain Important for alphaIIbbeta3 Integrin Activation
J.Mol.Biol., 394, 2009
2KVP
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NMR STRUCTURE OF THE TALIN VBS3 DOMAIN, 1815-1973
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Critchley, D.R., Barsukov, I.L., Roberts, G.C.
Deposit date:2010-03-24
Release date:2010-05-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The domain structure of talin: Residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.
Febs Lett., 584, 2010
2L10
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STRUCTURE OF THE TALIN ROD RESIDUES, DOMAIN C
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.
Deposit date:2010-07-22
Release date:2011-08-31
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2L7A
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SOLUTION STRUCTURE OF THE TALIN VBS2B DOMAIN
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.
Deposit date:2010-12-06
Release date:2011-12-21
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2L7N
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NMR STRUCTURE OF THE B DOMAIN OF TALIN
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Barsukov, I.L., Roberts, G.C.K., Critchley, D.R.
Deposit date:2010-12-14
Release date:2011-12-14
Last modified:2014-01-15
Method:SOLUTION NMR
Cite:RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
J.Biol.Chem., 288, 2013
2LQG
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SOLUTION STRUCTURE OF THE R4 DOMAIN OF TALIN
Descriptor:Talin-1
Authors:Goult, B.T., Gingras, A.R., Bate, N., Roberts, G.C.K., Barsukov, I.L., Critchley, D.R.
Deposit date:2012-03-06
Release date:2013-02-13
Last modified:2013-04-24
Method:SOLUTION NMR
Cite:RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover.
J.Biol.Chem., 288, 2013
3DYJ
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CRYSTAL STRUCTURE A TALIN ROD FRAGMENT
Descriptor:TALIN-1
Authors:Gingras, A.R., Joyce, M.G., Critchley, D.R., Emsley, J.
Deposit date:2008-07-28
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural determinants of integrin binding to the talin rod
J.Biol.Chem., 284, 2009
3G9W
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CRYSTAL STRUCTURE OF TALIN2 F2-F3 IN COMPLEX WITH THE INTEGRIN BETA1D CYTOPLASMIC TAIL
Descriptor:Talin-2, Integrin beta-1D, GLYCEROL, ...
Authors:Anthis, N.J., Wegener, K.L., Ye, F., Kim, C., Lowe, E.D., Vakonakis, I., Bate, N., Critchley, D.R., Ginsberg, M.H., Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
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