Author results

5N2U
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INFLUENZA D VIRUS NUCLEOPROTEIN
Descriptor:Nucleoprotein
Authors:Labaronne, A., Ruigrok, R.W.H., Crepin, T.
Deposit date:2017-02-08
Release date:2018-02-28
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of the nucleoprotein of Influenza D shows that all Orthomyxoviridae nucleoproteins have a similar NPCORE, with or without a NPTAILfor nuclear transport.
Sci Rep, 9, 2019
4WCY
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FAB FRAGMENT OF MOUSE AZ130 MONOCLONAL ANTIBODY
Descriptor:AZ130 Heavy chain, AZ130 Light chain, GLYCEROL, ...
Authors:Fallecker, C., Tarbouriech, N., Habib, M., Crepin, T., Drouet, E.
Deposit date:2014-09-05
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fab fragment of mouse AZ130 monoclonal antibody
To Be Published
4WRT
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CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND VRNA PROMOTER (FORM FLUB2)
Descriptor:Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ...
Authors:Reich, S., Guilligay, D., Pflug, A., Cusack, S.
Deposit date:2014-10-25
Release date:2014-11-19
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
4WSA
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CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE BOUND TO THE VRNA PROMOTER (FLUB1 FORM)
Descriptor:Influenza B vRNA promoter 3' end, Influenza B vRNA promoter 5' end, PA, ...
Authors:Reich, S., Guilligay, D., Pflug, A., Cusack, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
4WSB
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BAT INFLUENZA A POLYMERASE WITH BOUND VRNA PROMOTER
Descriptor:Polymerase PA, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Cusack, S., Pflug, A., Guilligay, D., Reich, S.
Deposit date:2014-10-26
Release date:2014-11-19
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Nature, 516, 2014
4C0S
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MAMMALIAN TRANSLATION ELONGATION FACTOR EEF1A2
Descriptor:ELONGATION FACTOR 1-ALPHA 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Crepin, T., Shalak, V.F., Yaremchuk, A.D., Vlasenko, D.O., McCarthy, A.A., Negrutskii, B.S., Tukalo, M.A., El'skaya, A.V.
Deposit date:2013-08-07
Release date:2014-08-27
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Mammalian Translation Elongation Factor Eef1A2: X-Ray Structure and New Features of Gdp/GTP Exchange Mechanism in Higher Eukaryotes
Nucleic Acids Res., 42, 2014
4CGS
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE PA SUBUNIT OF DHORI VIRUS POLYMERASE
Descriptor:POLYMERASE SUBUNIT PA, GLYCEROL
Authors:Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
Deposit date:2013-11-26
Release date:2014-02-05
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CGX
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE PA SUBUNIT OF THOGOTO VIRUS POLYMERASE (FORM 1)
Descriptor:POLYMERASE ACIDIC PROTEIN
Authors:Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
Deposit date:2013-11-27
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHC
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE PA SUBUNIT OF THOGOTO VIRUS POLYMERASE (FORM 2)
Descriptor:POLYMERASE ACIDIC PROTEIN
Authors:Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHD
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CRYSTAL STRUCTURE OF THE '627' DOMAIN OF THE PB2 SUBUNIT OF THOGOTO VIRUS POLYMERASE
Descriptor:POLYMERASE ACIDIC PROTEIN
Authors:Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHE
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CRYSTAL STRUCTURE OF THE PUTATIVE CAP-BINDING DOMAIN OF THE PB2 SUBUNIT OF THOGOTO VIRUS POLYMERASE
Descriptor:POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CHF
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CRYSTAL STRUCTURE OF THE PUTATIVE CAP-BINDING DOMAIN OF THE PB2 SUBUNIT OF THOGOTO VIRUS POLYMERASE (FORM 2)
Descriptor:POLYMERASE BASIC PROTEIN 2
Authors:Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
Deposit date:2013-12-01
Release date:2014-02-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
3ZDO
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TETRAMERIZATION DOMAIN OF MEASLES VIRUS PHOSPHOPROTEIN
Descriptor:PHOSPHOPROTEIN, (4R)-2-METHYLPENTANE-2,4-DIOL
Authors:Communie, G., Crepin, T., Jensen, M.R., Blackledge, M., Ruigrok, R.W.H.
Deposit date:2012-11-29
Release date:2013-04-24
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure of the Tetramerization Domain of Measles Virus Phosphoprotein.
J.Virol., 87, 2013
3ZDP
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R416A MONOMERIC NUCLEOPROTEIN OF INFLUENZA A VIRUS
Descriptor:NUCLEOCAPSID PROTEIN, POTASSIUM ION
Authors:Chenavas, S., Ruigrok, R.W.H., Crepin, T.
Deposit date:2012-11-29
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Monomeric Nucleoprotein of Influenza a Virus.
Plos Pathog., 9, 2013
3ZJT
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TERNARY COMPLEX OF E.COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU)574 AND THE BENZOXABOROLE AN3017 IN THE EDITING CONFORMATION
Descriptor:LEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION
Authors:Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
Deposit date:2013-01-18
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
3ZJU
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TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN3016 IN THE EDITING CONFORMATION
Descriptor:LEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION
Authors:Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
Deposit date:2013-01-18
Release date:2013-04-17
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
3ZJV
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TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN3213 IN THE EDITING CONFORMATION
Descriptor:LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR
Authors:Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
Deposit date:2013-01-18
Release date:2013-04-17
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
4AQ7
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND LEUCYL-ADENYLATE ANALOGUE IN THE AMINOACYLATION CONFORMATION
Descriptor:LEUCINE--TRNA LIGASE, E. COLI TRNALEU UAA ISOACCEPTOR, ZINC ION, ...
Authors:Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
Deposit date:2012-04-13
Release date:2012-06-13
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
4ARC
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND LEUCINE IN THE EDITING CONFORMATION
Descriptor:LEUCINE--TRNA LIGASE, TRNA-LEU5 (UAA ISOACCEPTOR), LEUCINE, ...
Authors:Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
4ARI
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN2679 IN THE EDITING CONFORMATION
Descriptor:LEUCINE--TRNA LIGASE, TRNA-LEU5 (UAA ISOACEPTOR), GLYCEROL, ...
Authors:Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
Deposit date:2012-04-24
Release date:2012-06-13
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
4AS1
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TERNARY COMPLEX OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN2679 IN THE EDITING CONFORMATION
Descriptor:LEUCINE--TRNA LIGASE, TRNA-LEU5 (UAA ISOACEPTOR), MAGNESIUM ION
Authors:Palencia, A., Crepin, T., Vu, M.T., Lincecum Jr, T.L., Martinis, S.A., Cusack, S.
Deposit date:2012-04-27
Release date:2012-06-13
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
2XGT
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ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH THE SULPHAMOYL ANALOGUE OF ASPARAGINYL-ADENYLATE
Descriptor:ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, GLYCEROL, ...
Authors:Crepin, T., Haertlein, M., Kron, M., Cusack, S.
Deposit date:2010-06-07
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
2XTI
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ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH ATP:MG AND L-ASP-BETA-NOH ADENYLATE:PPI:MG
Descriptor:ASPARAGINYL-TRNA SYNTHETASE\, CYTOPLASMIC\, PUTATIVE, ...
Authors:Crepin, T., Haertlein, M., Kron, M., Cusack, S.
Deposit date:2010-10-10
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
3L32
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STRUCTURE OF THE DIMERISATION DOMAIN OF THE RABIES VIRUS PHOSPHOPROTEIN
Descriptor:Phosphoprotein
Authors:Ivanov, I., Crepin, T., Jamin, M., Ruigrok, R.W.H.
Deposit date:2009-12-16
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the dimerisation domain of the rabies virus phosphoprotein
J.Virol., 2010
2KQR
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN (RESIDUES 1-111) OF BRUGIA MALAYI ASPARAGINYL-TRNA SYNTHETASE
Descriptor:Asparaginyl-tRNA synthetase, cytoplasmic
Authors:Volkman, B.F., Peterson, F.C., Kron, M.A., Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2009-11-16
Release date:2009-12-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
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