1RU0
| Crystal structure of DCoH2, a paralog of DCoH, the Dimerization Cofactor of HNF-1 | Descriptor: | DcoH-like protein DCoHm | Authors: | Rose, R.B, Pullen, K.E, Bayle, J.H, Crabtree, G.R, Alber, T. | Deposit date: | 2003-12-10 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2 Biochemistry, 43, 2004
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1NFA
| HUMAN TRANSCRIPTION FACTOR NFATC DNA BINDING DOMAIN, NMR, 10 STRUCTURES | Descriptor: | HUMAN TRANSCRIPTION FACTOR NFATC1 | Authors: | Wolfe, S.A, Zhou, P, Dotsch, V, Chen, L, You, A, Ho, S.N, Crabtree, G.R, Wagner, G, Verdine, G.L. | Deposit date: | 1997-01-18 | Release date: | 1997-04-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc. Nature, 385, 1997
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1F93
| CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE DIMERIZATION DOMAIN OF HNF-1 ALPHA AND THE COACTIVATOR DCOH | Descriptor: | DIMERIZATION COFACTOR OF HEPATOCYTE NUCLEAR FACTOR 1-ALPHA, HEPATOCYTE NUCLEAR FACTOR 1-ALPHA | Authors: | Rose, R.B, Bayle, J.H, Endrizzi, J.A, Cronk, J.D, Crabtree, G.R, Alber, T. | Deposit date: | 2000-07-06 | Release date: | 2000-09-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha. Nat.Struct.Biol., 7, 2000
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1DCH
| CRYSTAL STRUCTURE OF DCOH, A BIFUNCTIONAL, PROTEIN-BINDING TRANSCRIPTION COACTIVATOR | Descriptor: | DCOH (DIMERIZATION COFACTOR OF HNF-1), SULFATE ION | Authors: | Endrizzi, J.A, Cronk, J.D, Wang, W, Crabtree, G.R, Alber, T. | Deposit date: | 1995-01-24 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of DCoH, a bifunctional, protein-binding transcriptional coactivator. Science, 268, 1995
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3HXA
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1JB6
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1DCP
| DCOH, A BIFUNCTIONAL PROTEIN-BINDING TRANSCRIPTIONAL COACTIVATOR, COMPLEXED WITH BIOPTERIN | Descriptor: | 7,8-DIHYDROBIOPTERIN, DCOH | Authors: | Cronk, J.D, Endrizzi, J.A, Alber, T. | Deposit date: | 1996-05-16 | Release date: | 1996-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | High-resolution structures of the bifunctional enzyme and transcriptional coactivator DCoH and its complex with a product analogue. Protein Sci., 5, 1996
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1G39
| WILD-TYPE HNF-1ALPHA DIMERIZATION DOMAIN | Descriptor: | HEPATOCYTE NUCLEAR FACTOR 1-ALPHA | Authors: | Rose, R.B, Endrizzi, J.A, Cronk, J.D, Holton, J, Alber, T. | Deposit date: | 2000-10-23 | Release date: | 2001-01-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | High-resolution structure of the HNF-1alpha dimerization domain. Biochemistry, 39, 2000
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1G2Y
| HNF-1ALPHA DIMERIZATION DOMAIN, WITH SELENOMETHIONINE SUBSTITUED AT LEU 12 | Descriptor: | HEPATOCYTE NUCLEAR FACTOR 1-ALPHA | Authors: | Rose, R.B, Endrizzi, J.A, Cronk, J.D, Holton, J, Alber, T. | Deposit date: | 2000-10-23 | Release date: | 2001-01-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | High-resolution structure of the HNF-1alpha dimerization domain. Biochemistry, 39, 2000
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1DCO
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1G2Z
| DIMERIZATION DOMAIN OF HNF-1ALPHA WITH A LEU 13 SELENOMETHIONINE SUBSTITUTION | Descriptor: | HEPATOCYTE NUCLEAR FACTOR 1-ALPHA | Authors: | Rose, R.B, Endrizzi, J.A, Cronk, J.D, Holton, J, Alber, T. | Deposit date: | 2000-10-23 | Release date: | 2001-01-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | High-resolution structure of the HNF-1alpha dimerization domain. Biochemistry, 39, 2000
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