Author results

1URW
  • Download 1urw
  • View 1urw
Molmil generated image of 1urw
CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-B]PYRIDAZINE
Descriptor:CELL DIVISION PROTEIN KINASE 2, 2-[4-(N-(3-DIMETHYLAMINOPROPYL)SULPHAMOYL)ANILINO]-
Authors:Byth, K.F., Cooper, N., Culshaw, J.D., Heaton, D.W., Oakes, S.E., Minshull, C.A., Norman, R.A., Pauptit, R.A., Tucker, J.A., Breed, J., Pannifer, A., Rowsell, S., Stanway, J.J., Valentine, A.L., Thomas, A.P.
Deposit date:2003-11-11
Release date:2004-04-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Imidazo[1,2-B]Pyridazines: A Potent and Selective Class of Cyclin-Dependent Kinase Inhibitors
Bioorg.Med.Chem.Lett., 14, 2004
2K4L
  • Download 2k4l
  • View 2k4l
Molmil generated image of 2k4l
SOLUTION STRUCTURE OF A 2:1C2-(2-NAPHTHYL)PYRROLO[2,1-C][1,4]BENZODIAZEPINE (PBD) DNA ADDUCT: MOLECULAR BASIS FOR UNEXPECTEDLY HIGH DNA HELIX STABILIZATION.
Descriptor:5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DAP*DAP*DAP*DGP*DAP*DTP*DT)-3', (11aS)-7,8-dimethoxy-2-naphthalen-2-yl-1,10,11,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one
Authors:Antonow, D., Barata, T., Jenkins, T.C., Parkinson, G.N., Howard, P.W., Thurston, D.E., Zloh, M.
Deposit date:2008-06-13
Release date:2008-10-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a 2:1 C2-(2-naphthyl) pyrrolo[2,1-c][1,4]benzodiazepine DNA adduct: molecular basis for unexpectedly high DNA helix stabilization.
Biochemistry, 47, 2008