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4AVX
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HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE (HGS-HRS) BOUND TO AN IP2 COMPOUND AT 1.68 A RESOLUTION
Descriptor:HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, 1,2-ETHANEDIOL, ZINC ION, ...
Authors:Williams, E., Canning, P., Shrestha, L., Krojer, T., Vollmar, M., Slowey, A., Conway, S., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bullock, A.
Deposit date:2012-05-30
Release date:2012-06-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Crystal Structure of the Tandem Vhs and Fyve Domains of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) Bound to an Ip2 Compound at 1.68 A Resolution
To be Published
4GPJ
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH A ISOXAZOLYLBENZIMIDAZOLE LIGAND
Descriptor:Bromodomain-containing protein 4, (1R)-6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-phenyl-2,3-dihydro-1H-inden-1-ol, 1,2-ETHANEDIOL, ...
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Felletar, I., Heightman, T.D., Brennan, P., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2012-08-21
Release date:2012-10-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET Bromodomains
TO BE PUBLISHED