Author results

1IC1
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THE CRYSTAL STRUCTURE FOR THE N-TERMINAL TWO DOMAINS OF ICAM-1
Descriptor:INTERCELLULAR ADHESION MOLECULE-1, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Casasnovas, J.M., Stehle, T., Liu, J.-H., Wang, J.-H., Springer, T.A.
Deposit date:1998-03-09
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1.
Proc.Natl.Acad.Sci.USA, 95, 1998
1ZXQ
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THE CRYSTAL STRUCTURE OF ICAM-2
Descriptor:INTERCELLULAR ADHESION MOLECULE-2, N-ACETYL-D-GLUCOSAMINE
Authors:Casasnovas, J.M., Springer, T.A., Harrison, S.C., Wang, J.-H.
Deposit date:1997-03-04
Release date:1997-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface.
Nature, 387, 1997
1BQS
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THE CRYSTAL STRUCTURE OF MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1 (MADCAM-1)
Descriptor:PROTEIN (MUCOSAL ADDRESSIN CELL ADHESION MOLECULE-1), 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Tan, K., Casasnovas, J.M., Liu, J.H., Briskin, M.J., Springer, T.A., Wang, J.-H.
Deposit date:1998-08-18
Release date:1999-08-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition.
Structure, 6, 1998
2OR7
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TIM-2
Descriptor:T-cell immunoglobulin and mucin domain-containing protein 2, ACETATE ION
Authors:Santiago, C., Ballesteros, A., Kaplan, G.G., Casasnovas, J.M.
Deposit date:2007-02-02
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family.
Immunity, 26, 2007
2OR8
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TIM-1
Descriptor:Hepatitis A virus cellular receptor 1 homolog, ACETATE ION
Authors:Santiago, C., Ballesteros, A., Kaplan, G.G., Casasnovas, J.M.
Deposit date:2007-02-02
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family.
Immunity, 26, 2007
3BI9
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TIM-4
Descriptor:T-cell immunoglobulin and mucin domain-containing protein 4, ACETATE ION
Authors:Santiago, C., Ballesteros, A., Kaplan, G.G., Freeman, G.J., Casasnovas, J.M.
Deposit date:2007-11-30
Release date:2008-01-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds.
Immunity, 27, 2007
3BIA
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TIM-4 IN COMPLEX WITH SODIUM POTASSIUM TARTRATE
Descriptor:T-cell immunoglobulin and mucin domain-containing protein 4, SODIUM ION, L(+)-TARTARIC ACID
Authors:Santiago, C., Ballesteros, A., Kaplan, G.G., Freeman, G.J., Casasnovas, J.M.
Deposit date:2007-11-30
Release date:2008-01-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds.
Immunity, 27, 2007
3BIB
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TIM-4 IN COMPLEX WITH PHOSPHATIDYLSERINE
Descriptor:T-cell immunoglobulin and mucin domain-containing protein 4, SODIUM ION, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE
Authors:Santiago, C., Ballesteros, A., Kaplan, G.G., Freeman, G.J., Casasnovas, J.M.
Deposit date:2007-11-30
Release date:2008-01-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of T Cell Immunoglobulin Mucin Protein 4 Show a Metal-Ion-Dependent Ligand Binding Site where Phosphatidylserine Binds.
Immunity, 27, 2007
3INB
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STRUCTURE OF THE MEASLES VIRUS HEMAGGLUTININ BOUND TO THE CD46 RECEPTOR
Descriptor:Hemagglutinin glycoprotein, Membrane cofactor protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Santiago, C., Celma, M.L., Stehle, T., Casasnovas, J.M.
Deposit date:2009-08-12
Release date:2009-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of the measles virus hemagglutinin bound to the CD46 receptor
Nat.Struct.Mol.Biol., 17, 2010
3KAA
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STRUCTURE OF TIM-3 IN COMPLEX WITH PHOSPHATIDYLSERINE
Descriptor:Hepatitis A virus cellular receptor 2, CALCIUM ION, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE
Authors:Ballesteros, A., Santiago, C., Casasnovas, J.M.
Deposit date:2009-10-19
Release date:2010-01-26
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (3.002 Å)
Cite:T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.
J.Immunol., 184, 2010
3O74
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CRYSTAL STRUCTURE OF CRA TRANSCRIPTIONAL DUAL REGULATOR FROM PSEUDOMONAS PUTIDA
Descriptor:Fructose transport system repressor FruR, GLYCEROL
Authors:Chavarria, M., Santiago, C., Platero, R., Krell, T., Casasnovas, J.M., de Lorenzo, V.
Deposit date:2010-07-30
Release date:2011-01-12
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fructose 1-phosphate is the preferred effector of the metabolic regulator Cra of Pseudomonas putida
J.Biol.Chem., 286, 2011
3O75
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CRYSTAL STRUCTURE OF CRA TRANSCRIPTIONAL DUAL REGULATOR FROM PSEUDOMONAS PUTIDA IN COMPLEX WITH FRUCTOSE 1-PHOSPHATE'
Descriptor:Fructose transport system repressor FruR, 1-O-phosphono-beta-D-fructofuranose
Authors:Chavarria, M., Santiago, C., Platero, R., Krell, T., Casasnovas, J.M., de Lorenzo, V.
Deposit date:2010-07-30
Release date:2011-01-12
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fructose 1-phosphate is the preferred effector of the metabolic regulator Cra of Pseudomonas putida
J.Biol.Chem., 286, 2011
3O8E
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STRUCTURE OF EXTRACELLLAR PORTION OF CD46 IN COMPLEX WITH ADENOVIRUS TYPE 11 KNOB
Descriptor:Fiber 36.1 kDa protein, Membrane cofactor protein, DITHIANE DIOL, ...
Authors:Persson, B.D., Schmitz, N.B., Casasnovas, J.M., Stehle, T.
Deposit date:2010-08-03
Release date:2010-10-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structure of the extracellular portion of CD46 provides insights into its interactions with complement proteins and pathogens.
Plos Pathog., 6, 2010
4F2M
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CRYSTAL STRUCTURE OF A TGEV CORONAVIRUS SPIKE FRAGMENT IN COMPLEX WITH THE TGEV NEUTRALIZING MONOCLONAL ANTIBODY 1AF10
Descriptor:monoclonal antibody 1AF10, heavy chain, light chain, ...
Authors:Reguera, J., Santiago, C., Mudgal, G., Ordono, D., Enjuanes, L., Casasnovas, J.M.
Deposit date:2012-05-08
Release date:2012-08-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.
Plos Pathog., 8, 2012
4F5C
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CRYSTAL STRUCTURE OF THE SPIKE RECEPTOR BINDING DOMAIN OF A PORCINE RESPIRATORY CORONAVIRUS IN COMPLEX WITH THE PIG AMINOPEPTIDASE N ECTODOMAIN
Descriptor:Aminopeptidase N, PRCV spike protein, ZINC ION, ...
Authors:Santiago, C., Reguera, J., Gaurav, M., Ordono, D., Enjuanes, L., Casasnovas, J.M.
Deposit date:2012-05-13
Release date:2012-08-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.
Plos Pathog., 8, 2012
4OI9
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CRYSTAL STRUCTURE OF ICAM-5 D1-D4 ECTODOMAIN FRAGMENT, SPACE GROUP P21
Descriptor:Intercellular adhesion molecule 5, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Recacha, R., Jimenez, D., Tian, L., Barredo, R., Ghamberg, C., Casasnovas, J.M.
Deposit date:2014-01-19
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions.
Acta Crystallogr.,Sect.D, 70, 2014
4OIA
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CRYSTAL STRUCTURE OF ICAM-5 D1-D4 ECTODOMAIN FRAGMENT, SPACE GROUP P4322
Descriptor:Intercellular adhesion molecule 5, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Recacha, R., Jimenez, D., Tian, L., Barredo, R., Ghamberg, C., Casasnovas, J.M.
Deposit date:2014-01-19
Release date:2014-07-16
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions.
Acta Crystallogr.,Sect.D, 70, 2014
4OIB
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CRYSTAL STRUCTURE OF ICAM-5 D1-D4 ECTODOMAIN FRAGMENT, SPACE GROUP R3
Descriptor:Intercellular adhesion molecule 5, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Recacha, R., Jimenez, D., Tian, L., Barredo, R., Ghamberg, C., Casasnovas, J.M.
Deposit date:2014-01-19
Release date:2014-07-16
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions.
Acta Crystallogr.,Sect.D, 70, 2014
5LDS
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STRUCTURE OF THE PORCINE AMINOPEPTIDASE N ECTODOMAIN
Descriptor:Aminopeptidase N, ZINC ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Santiago, C., Reguera, J., Mudgal, G., Casasnovas, J.M.
Deposit date:2016-06-27
Release date:2017-04-05
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
5LG6
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STRUCTURE OF THE DEGLYCOSYLATED PORCINE AMINOPEPTIDASE N ECTODOMAIN
Descriptor:Aminopeptidase N, N-ACETYL-D-GLUCOSAMINE, ZINC ION
Authors:Santiago, C., Reguera, J., Mudgal, G., Casasnovas, J.M.
Deposit date:2016-07-06
Release date:2017-04-12
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
5LHD
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STRUCTURE OF GLYCOSYLATED HUMAN AMINOPEPTIDASE N
Descriptor:Aminopeptidase N, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Recacha, R., Mudgal, G., Santiago, C., Casasnovas, J.M.
Deposit date:2016-07-11
Release date:2017-04-05
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.
Sci Rep, 7, 2017
1CKL
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N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP)
Descriptor:PROTEIN (CD46), N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Casasnovas, J., Larvie, M., Stehle, T.
Deposit date:1999-04-22
Release date:1999-06-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of two CD46 domains reveals an extended measles virus-binding surface.
EMBO J., 18, 1999
1T0P
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STRUCTURAL BASIS OF ICAM RECOGNITION BY INTEGRIN ALPAHLBETA2 REVEALED IN THE COMPLEX STRUCTURE OF BINDING DOMAINS OF ICAM-3 AND ALPHALBETA2 AT 1.65 A
Descriptor:Integrin alpha-L, Intercellular adhesion molecule-3, MAGNESIUM ION, ...
Authors:Song, G., Yang, Y.T., Liu, J.H., Shimaoko, M., Springer, T.A., Wang, J.H.
Deposit date:2004-04-12
Release date:2005-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:An atomic resolution view of ICAM recognition in a complex between the binding domains of ICAM-3 and integrin alphaLbeta2.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2O39
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HUMAN ADENOVIRUS TYPE 11 KNOB IN COMPLEX WITH DOMAINS SCR1 AND SCR2 OF CD46 (MEMBRANE COFACTOR PROTEIN, MCP)
Descriptor:Fiber protein, Membrane cofactor protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Persson, D.B., Reiter, D.M., Arnberg, N., Stehle, T.
Deposit date:2006-12-01
Release date:2007-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Adenovirus type 11 binding alters the conformation of its receptor CD46.
Nat.Struct.Mol.Biol., 14, 2007
3BN3
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CRYSTAL STRUCTURE OF ICAM-5 IN COMPLEX WITH AL I DOMAIN
Descriptor:Integrin alpha-L, Intercellular adhesion molecule 5, MAGNESIUM ION, ...
Authors:Zhang, H., Springer, T.A., Wang, J.-h.
Deposit date:2007-12-13
Release date:2008-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:An unusual allosteric mobility of the C-terminal helix of a high-affinity alpha L integrin I domain variant bound to ICAM-5
Mol.Cell, 31, 2008
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