Author results

6CJN
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CRYSTAL STRUCTURE OF CHALCONE ISOMERASE FROM MEDICAGO SATIVA WITH THE G95T MUTATION
Descriptor:Chalcone--flavonone isomerase 1, SULFATE ION
Authors:Burke, J.R., La Clair, J.J., Philippe, R.N., Pabis, A., Jez, J.M., Cortina, G., Kaltenbach, M., Bowman, M.E., Woods, K.B., Nelson, A.T., Tawfik, D.S., Kamerlin, S.C.L., Noel, J.P.
Deposit date:2018-02-26
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dynamics and Bifunctional Substrate Activation by an Arginine Drive Catalysis in Plant Chalcone Isomerases
To Be Published
6CJO
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CRYSTAL STRUCTURE OF CHALCONE ISOMERASE FROM MEDICAGO SATIVA WITH THE G95S MUTATION.
Descriptor:Chalcone--flavonone isomerase 1, SULFATE ION
Authors:Burke, J.R., La Clair, J.J., Philippe, R.N., Pabis, A., Jez, J.M., Cortina, G., Kaltenbach, M., Bowman, M.E., Woods, K.B., Nelson, A.T., Tawfik, D.S., Kamerlin, S.C.L., Noel, J.P.
Deposit date:2018-02-26
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dynamics and Bifunctional Substrate Activation by an Arginine Drive Catalysis in Plant Chalcone Isomerases
To Be Published
5U3Q
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 1
Descriptor:Peroxisome proliferator-activated receptor delta, 6-(2-{[([1,1'-biphenyl]-4-carbonyl)(propan-2-yl)amino]methyl}phenoxy)hexanoic acid, HEPTYL-BETA-D-GLUCOPYRANOSIDE, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3R
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 2
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, 6-[2-({[4-(furan-2-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3S
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 3
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({[4-(furan-3-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, HEPTYL-BETA-D-GLUCOPYRANOSIDE, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3T
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 4
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({(propan-2-yl)[4-(thiophen-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, HEPTYL-BETA-D-GLUCOPYRANOSIDE, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3U
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 5
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({cyclopentyl[4-(furan-2-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, S-1,2-PROPANEDIOL, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3V
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 6
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, 6-[2-({cyclopentyl[4-(furan-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3W
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 7
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, 6-(2-{[([1,1'-biphenyl]-4-carbonyl)(cyclopropyl)amino]methyl}phenoxy)hexanoic acid, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3X
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 8
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({cyclopropyl[4-(pyridin-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, HEPTYL-BETA-D-GLUCOPYRANOSIDE, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3Y
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 9
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, 6-[2-({cyclopropyl[4-(furan-2-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U3Z
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 10
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({cyclopropyl[4-(furan-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, S-1,2-PROPANEDIOL, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U40
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 15
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({benzyl[4-(furan-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U41
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 16
Descriptor:Peroxisome proliferator-activated receptor delta, 6-[2-({benzyl[4-(thiophen-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U42
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 11
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, 6-(2-{[cyclopropyl(3'-methoxy[1,1'-biphenyl]-4-carbonyl)amino]methyl}phenoxy)hexanoic acid, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U43
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 12
Descriptor:Peroxisome proliferator-activated receptor delta, 6-(2-{[cyclopropyl(4'-methoxy[1,1'-biphenyl]-4-carbonyl)amino]methyl}phenoxy)hexanoic acid, S-1,2-PROPANEDIOL, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U44
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 13
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, S-1,2-PROPANEDIOL, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U45
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH SPECIFIC AGONIST 14
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, 6-(2-{[cyclopropyl(3'-fluoro[1,1'-biphenyl]-4-carbonyl)amino]methyl}phenoxy)hexanoic acid, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U46
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HUMAN PPARDELTA LIGAND-BINDING DOMAIN IN COMPLEXED WITH GW501516
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, S-1,2-PROPANEDIOL, ...
Authors:Wu, C.-C., Baiga, T.J., Downes, M., La Clair, J.J., Atkins, A.R., Richard, S.B., Stockley-Noel, T.A., Bowman, M.E., Evans, R.M., Noel, J.P.
Deposit date:2016-12-03
Release date:2017-03-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4QTZ
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CRYSTAL STRUCTURE OF CINNAMYL-ALCOHOL DEHYDROGENASE 2
Descriptor:Dihydroflavonol-4-reductase
Authors:Pan, H., Wang, X.
Deposit date:2014-07-10
Release date:2014-10-01
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4QUK
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CRYSTAL STRUCTURE OF CINNAMYL-ALCOHOL DEHYDROGENASE 2 MUTANT K169A
Descriptor:Dihydroflavonol-4-reductase
Authors:Pan, H., Wang, X.
Deposit date:2014-07-10
Release date:2014-10-01
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1S
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CRYSTAL STRUCTURE OF PETUNIA HYDRIDA CINNAMOYL-COA REDUCTASE
Descriptor:cinnamoyl CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Noel, J.P., Louie, G.V., Bowman, M.E., Bomati, E.K.
Deposit date:2014-08-07
Release date:2014-10-01
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1T
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CRYSTAL STRUCTURE OF PETUNIA HYDRIDA CINNAMOYL-COA REDUCTASE
Descriptor:cinnamoyl CoA reductase, molecular iodine
Authors:Noel, J.P., Louie, G.V., Bowman, M.E., Bomati, E.K.
Deposit date:2014-08-07
Release date:2014-10-01
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1U
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CRYSTAL STRUCTURE OF MEDICAGO TRUNCATULA CINNAMOYL-COA REDUCTASE
Descriptor:Cinnamoyl CoA reductase, ACETATE ION
Authors:Noel, J.P., Bomati, E.K., Louie, G.V., Bowman, M.E.
Deposit date:2014-08-07
Release date:2014-10-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
3TDB
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HUMAN PIN1 BOUND TO TRANS PEPTIDOMIMETIC INHIBITOR
Descriptor:Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, N-[(1E,2R)-1-[(2R)-2-{[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}cyclopentylidene]-3-(phosphonooxy)propan-2-yl]-L-phenylalaninamide, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL
Authors:Zhang, M., Zhang, Y.
Deposit date:2011-08-10
Release date:2012-06-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.267 Å)
Cite:Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code.
Acs Chem.Biol., 7, 2012